Synthesis of palladium(II) diimine complexes and their catalytic potential in sonogashira cross coupling reaction
Cross-coupling reactions catalyzed by various transition metal com- plexes are the most powerful synthetic tools for the generation of C = C and C ≡C bonds. Significant effort s have been put into the modification of ligands to increase the catalytic efficiency of the transition metal complexes. In...
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| Format: | Article |
| Language: | English |
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Elsevier B.V.
2016
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| Online Access: | http://ir.unimas.my/id/eprint/13559/ http://ir.unimas.my/id/eprint/13559/1/Suzie%20Hui.pdf |
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| author | Hui, Suzie Chin Kuan Meng, Guan Tay Chao, Liu |
| author_facet | Hui, Suzie Chin Kuan Meng, Guan Tay Chao, Liu |
| author_sort | Hui, Suzie Chin Kuan |
| building | UNIMAS Institutional Repository |
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| description | Cross-coupling reactions catalyzed by various transition metal com- plexes are the most powerful synthetic tools for the generation of C = C and C ≡C bonds. Significant effort s have been put into the modification of ligands to increase the catalytic efficiency of the transition metal complexes. In most cases, attention is only paid to highly efficient catalysts and unsuccessful examples are often ig- nored. In this work, four diimine compounds, R-dab, were synthe- sized by condensation reaction and then reacted with the precur- sor [PdCl 2 (MeCN) 2 ] to form a palladium(II) diimine, [PdCl 2 (R-dab)], complex. Our initial hypothesis was that the strong trans -effect from the diimine ligand in [PdCl 2 (R-dab)] would enhance the rate of reductive elimination and subsequently promote the formation of cross coupling product. The catalytic efficiency of [PdCl 2 (R-dab)] complexes in Sonogashira cross coupling reactions were examined at a temperature of 70 °C by reacting methyl-4-bromobenzoate and 2-methylbut-3-yn-2-ol for 5 hours under nitrogen conditions. Un- fortunately, our results showed that the [PdCl 2 (R-dab)] complexes are incapable of inducing the formation of cross coupling product. Despite the fact that these cross-coupling reactions were unsuc- cessful, we set out to explain the reasons for this failure herein |
| first_indexed | 2025-11-15T06:39:34Z |
| format | Article |
| id | unimas-13559 |
| institution | Universiti Malaysia Sarawak |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T06:39:34Z |
| publishDate | 2016 |
| publisher | Elsevier B.V. |
| recordtype | eprints |
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| spelling | unimas-135592022-02-04T08:13:04Z http://ir.unimas.my/id/eprint/13559/ Synthesis of palladium(II) diimine complexes and their catalytic potential in sonogashira cross coupling reaction Hui, Suzie Chin Kuan Meng, Guan Tay Chao, Liu QD Chemistry Cross-coupling reactions catalyzed by various transition metal com- plexes are the most powerful synthetic tools for the generation of C = C and C ≡C bonds. Significant effort s have been put into the modification of ligands to increase the catalytic efficiency of the transition metal complexes. In most cases, attention is only paid to highly efficient catalysts and unsuccessful examples are often ig- nored. In this work, four diimine compounds, R-dab, were synthe- sized by condensation reaction and then reacted with the precur- sor [PdCl 2 (MeCN) 2 ] to form a palladium(II) diimine, [PdCl 2 (R-dab)], complex. Our initial hypothesis was that the strong trans -effect from the diimine ligand in [PdCl 2 (R-dab)] would enhance the rate of reductive elimination and subsequently promote the formation of cross coupling product. The catalytic efficiency of [PdCl 2 (R-dab)] complexes in Sonogashira cross coupling reactions were examined at a temperature of 70 °C by reacting methyl-4-bromobenzoate and 2-methylbut-3-yn-2-ol for 5 hours under nitrogen conditions. Un- fortunately, our results showed that the [PdCl 2 (R-dab)] complexes are incapable of inducing the formation of cross coupling product. Despite the fact that these cross-coupling reactions were unsuc- cessful, we set out to explain the reasons for this failure herein Elsevier B.V. 2016 Article PeerReviewed text en http://ir.unimas.my/id/eprint/13559/1/Suzie%20Hui.pdf Hui, Suzie Chin Kuan and Meng, Guan Tay and Chao, Liu (2016) Synthesis of palladium(II) diimine complexes and their catalytic potential in sonogashira cross coupling reaction. Chemical Data Collections, 3-4. pp. 8-14. ISSN 2405-8300 http://dx.doi.org/10.1016/j.cdc.2016.08.002 |
| spellingShingle | QD Chemistry Hui, Suzie Chin Kuan Meng, Guan Tay Chao, Liu Synthesis of palladium(II) diimine complexes and their catalytic potential in sonogashira cross coupling reaction |
| title | Synthesis of palladium(II) diimine complexes and their catalytic potential in sonogashira cross coupling reaction |
| title_full | Synthesis of palladium(II) diimine complexes and their catalytic potential in sonogashira cross coupling reaction |
| title_fullStr | Synthesis of palladium(II) diimine complexes and their catalytic potential in sonogashira cross coupling reaction |
| title_full_unstemmed | Synthesis of palladium(II) diimine complexes and their catalytic potential in sonogashira cross coupling reaction |
| title_short | Synthesis of palladium(II) diimine complexes and their catalytic potential in sonogashira cross coupling reaction |
| title_sort | synthesis of palladium(ii) diimine complexes and their catalytic potential in sonogashira cross coupling reaction |
| topic | QD Chemistry |
| url | http://ir.unimas.my/id/eprint/13559/ http://ir.unimas.my/id/eprint/13559/ http://ir.unimas.my/id/eprint/13559/1/Suzie%20Hui.pdf |