Etherification studies on chalcone derivative with series of bromoalkanes
This research consists of two strategies which consist of the synthesis of chalcone and the introduction of the alk yl groups. A series of I-bromoalkyl namely C6, C7, C8 and C9 were introduced to the hydroxychalcone which was prepared using Claisen-Schmidt condensation reaction between 4hydroxyaceto...
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| Format: | Final Year Project Report / IMRAD |
| Language: | English |
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Universiti Malaysia Sarawak (UNIMAS)
2008
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| Online Access: | http://ir.unimas.my/id/eprint/1347/ http://ir.unimas.my/id/eprint/1347/8/Nurazrina%20Binti%20Mohd%20Damanhuri%20%28fulltext%29.pdf |
| _version_ | 1848834744662360064 |
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| author | Nurazrina, Mohd Damanhuri |
| author_facet | Nurazrina, Mohd Damanhuri |
| author_sort | Nurazrina, Mohd Damanhuri |
| building | UNIMAS Institutional Repository |
| collection | Online Access |
| description | This research consists of two strategies which consist of the synthesis of chalcone and the introduction of the alk yl groups. A series of I-bromoalkyl namely C6, C7, C8 and C9 were introduced to the hydroxychalcone which was prepared using Claisen-Schmidt condensation reaction between 4hydroxyacetophenone and benzaldehyde. Another strategy was carried out by alkylation of 4hydroxyacetophenone prior to the synthesis of chalcone derivatives. The infrared (FT-IR) and the nuclear magnetic resonance eH and I3C) spectroscopy were used to analyzed the compound. This study is perfOim ed to determine the best strategy that will produce higher yield. The study also involve measuring the antibacterial properties ofthe synthesized chalcone on biological assay. |
| first_indexed | 2025-11-15T05:56:51Z |
| format | Final Year Project Report / IMRAD |
| id | unimas-1347 |
| institution | Universiti Malaysia Sarawak |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T05:56:51Z |
| publishDate | 2008 |
| publisher | Universiti Malaysia Sarawak (UNIMAS) |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | unimas-13472024-01-23T08:21:24Z http://ir.unimas.my/id/eprint/1347/ Etherification studies on chalcone derivative with series of bromoalkanes Nurazrina, Mohd Damanhuri QD Chemistry This research consists of two strategies which consist of the synthesis of chalcone and the introduction of the alk yl groups. A series of I-bromoalkyl namely C6, C7, C8 and C9 were introduced to the hydroxychalcone which was prepared using Claisen-Schmidt condensation reaction between 4hydroxyacetophenone and benzaldehyde. Another strategy was carried out by alkylation of 4hydroxyacetophenone prior to the synthesis of chalcone derivatives. The infrared (FT-IR) and the nuclear magnetic resonance eH and I3C) spectroscopy were used to analyzed the compound. This study is perfOim ed to determine the best strategy that will produce higher yield. The study also involve measuring the antibacterial properties ofthe synthesized chalcone on biological assay. Universiti Malaysia Sarawak (UNIMAS) 2008 Final Year Project Report / IMRAD NonPeerReviewed text en http://ir.unimas.my/id/eprint/1347/8/Nurazrina%20Binti%20Mohd%20Damanhuri%20%28fulltext%29.pdf Nurazrina, Mohd Damanhuri (2008) Etherification studies on chalcone derivative with series of bromoalkanes. [Final Year Project Report / IMRAD] (Unpublished) |
| spellingShingle | QD Chemistry Nurazrina, Mohd Damanhuri Etherification studies on chalcone derivative with series of bromoalkanes |
| title | Etherification studies on chalcone derivative with series of bromoalkanes |
| title_full | Etherification studies on chalcone derivative with series of bromoalkanes |
| title_fullStr | Etherification studies on chalcone derivative with series of bromoalkanes |
| title_full_unstemmed | Etherification studies on chalcone derivative with series of bromoalkanes |
| title_short | Etherification studies on chalcone derivative with series of bromoalkanes |
| title_sort | etherification studies on chalcone derivative with series of bromoalkanes |
| topic | QD Chemistry |
| url | http://ir.unimas.my/id/eprint/1347/ http://ir.unimas.my/id/eprint/1347/8/Nurazrina%20Binti%20Mohd%20Damanhuri%20%28fulltext%29.pdf |