Synthesis and Spectral Characterization of 4-Hydroxy-3- Methoxybenzaldehyde Derivatives

Vanillin plays an important role in flavouring and as aroma agent. Vanillin has been used as a chemical intermediate in pharmaceutical and chemical syntheses. Schiff base products have been proved to poses beneficial biological effect towards health. Fourteen vanillin derivatives were synthesized...

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Main Authors: Mohd Razip, Asaruddin, Sam, Ezekiel, Mohammad Farhan, Ariffeen, Md Abu, Affan
Format: Article
Language:English
Published: Universiti Malaysia Sarawak, (UNIMAS) 2015
Subjects:
Online Access:http://ir.unimas.my/id/eprint/13423/
http://ir.unimas.my/id/eprint/13423/1/Synthesis.pdf
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author Mohd Razip, Asaruddin
Sam, Ezekiel
Mohammad Farhan, Ariffeen
Md Abu, Affan
author_facet Mohd Razip, Asaruddin
Sam, Ezekiel
Mohammad Farhan, Ariffeen
Md Abu, Affan
author_sort Mohd Razip, Asaruddin
building UNIMAS Institutional Repository
collection Online Access
description Vanillin plays an important role in flavouring and as aroma agent. Vanillin has been used as a chemical intermediate in pharmaceutical and chemical syntheses. Schiff base products have been proved to poses beneficial biological effect towards health. Fourteen vanillin derivatives were synthesized via Schiff base reaction using p-vanillin as the starting material reacted with 2-aminobenzenethiol, furan-2-carbohydrazide, 2- hydrazinylpyridine, 4-hydroxybenzohydrazide, acetohydrazide, benzohydrazide, (diphenylmethylidene) hydrazine, pyridine-4-carbohydrazide, benzene-1,2-diamine, phenylhydrazine, 2-hydroxybenzohydrazide, 1,3- benzothiazol-2-amine, 1-cyclohexylthiourea respectively. All of the compounds were characterized by elemental analysis, FTIR and 1H NMR.
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publisher Universiti Malaysia Sarawak, (UNIMAS)
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spelling unimas-134232022-01-28T07:37:32Z http://ir.unimas.my/id/eprint/13423/ Synthesis and Spectral Characterization of 4-Hydroxy-3- Methoxybenzaldehyde Derivatives Mohd Razip, Asaruddin Sam, Ezekiel Mohammad Farhan, Ariffeen Md Abu, Affan QD Chemistry Vanillin plays an important role in flavouring and as aroma agent. Vanillin has been used as a chemical intermediate in pharmaceutical and chemical syntheses. Schiff base products have been proved to poses beneficial biological effect towards health. Fourteen vanillin derivatives were synthesized via Schiff base reaction using p-vanillin as the starting material reacted with 2-aminobenzenethiol, furan-2-carbohydrazide, 2- hydrazinylpyridine, 4-hydroxybenzohydrazide, acetohydrazide, benzohydrazide, (diphenylmethylidene) hydrazine, pyridine-4-carbohydrazide, benzene-1,2-diamine, phenylhydrazine, 2-hydroxybenzohydrazide, 1,3- benzothiazol-2-amine, 1-cyclohexylthiourea respectively. All of the compounds were characterized by elemental analysis, FTIR and 1H NMR. Universiti Malaysia Sarawak, (UNIMAS) 2015 Article PeerReviewed text en http://ir.unimas.my/id/eprint/13423/1/Synthesis.pdf Mohd Razip, Asaruddin and Sam, Ezekiel and Mohammad Farhan, Ariffeen and Md Abu, Affan (2015) Synthesis and Spectral Characterization of 4-Hydroxy-3- Methoxybenzaldehyde Derivatives. Borneo Journal of Resource Science and Technology, 5 (1). pp. 43-48. ISSN 229-9769 http://publisher.unimas.my/ojs/index.php/BJRST
spellingShingle QD Chemistry
Mohd Razip, Asaruddin
Sam, Ezekiel
Mohammad Farhan, Ariffeen
Md Abu, Affan
Synthesis and Spectral Characterization of 4-Hydroxy-3- Methoxybenzaldehyde Derivatives
title Synthesis and Spectral Characterization of 4-Hydroxy-3- Methoxybenzaldehyde Derivatives
title_full Synthesis and Spectral Characterization of 4-Hydroxy-3- Methoxybenzaldehyde Derivatives
title_fullStr Synthesis and Spectral Characterization of 4-Hydroxy-3- Methoxybenzaldehyde Derivatives
title_full_unstemmed Synthesis and Spectral Characterization of 4-Hydroxy-3- Methoxybenzaldehyde Derivatives
title_short Synthesis and Spectral Characterization of 4-Hydroxy-3- Methoxybenzaldehyde Derivatives
title_sort synthesis and spectral characterization of 4-hydroxy-3- methoxybenzaldehyde derivatives
topic QD Chemistry
url http://ir.unimas.my/id/eprint/13423/
http://ir.unimas.my/id/eprint/13423/
http://ir.unimas.my/id/eprint/13423/1/Synthesis.pdf