Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma
Nasopharyngeal Carcinoma (NPC) occurs as a consequence of multiple molecular events induced by environmental factors and Epstein-Barr virus (EBV) infections. The neoplastic processes may involve alterations of the tumor suppressor genes and oncogenes by genetic damage and interference with the norma...
| Main Author: | |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
Universiti Malaysia Sarawak, (UNIMAS)
2011
|
| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/13304/ http://ir.unimas.my/id/eprint/13304/2/Chua%20Suk%20Ngo%20ft.pdf |
| _version_ | 1848837376595460096 |
|---|---|
| author | Chua, Suk Ngo |
| author_facet | Chua, Suk Ngo |
| author_sort | Chua, Suk Ngo |
| building | UNIMAS Institutional Repository |
| collection | Online Access |
| description | Nasopharyngeal Carcinoma (NPC) occurs as a consequence of multiple molecular events induced by environmental factors and Epstein-Barr virus (EBV) infections. The neoplastic processes may involve alterations of the tumor suppressor genes and oncogenes by genetic damage and interference with the normal cellular functions by the EBV latent gene products. Overexpression of TNF receptor-associated factor 6 (TRAF6) has been reported to suppress orilP activity and loss of EBV from Burkitt's lymphoma cell line. The role of vigilin in cytoplasmic mRNA metabolism has been suggested whereby alterations in mRNA regulation by RNA binding protein have been reported in diverse cancer types. |
| first_indexed | 2025-11-15T06:38:41Z |
| format | Thesis |
| id | unimas-13304 |
| institution | Universiti Malaysia Sarawak |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T06:38:41Z |
| publishDate | 2011 |
| publisher | Universiti Malaysia Sarawak, (UNIMAS) |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | unimas-133042025-06-23T02:36:04Z http://ir.unimas.my/id/eprint/13304/ Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma Chua, Suk Ngo RB Pathology Nasopharyngeal Carcinoma (NPC) occurs as a consequence of multiple molecular events induced by environmental factors and Epstein-Barr virus (EBV) infections. The neoplastic processes may involve alterations of the tumor suppressor genes and oncogenes by genetic damage and interference with the normal cellular functions by the EBV latent gene products. Overexpression of TNF receptor-associated factor 6 (TRAF6) has been reported to suppress orilP activity and loss of EBV from Burkitt's lymphoma cell line. The role of vigilin in cytoplasmic mRNA metabolism has been suggested whereby alterations in mRNA regulation by RNA binding protein have been reported in diverse cancer types. Universiti Malaysia Sarawak, (UNIMAS) 2011 Thesis NonPeerReviewed text en http://ir.unimas.my/id/eprint/13304/2/Chua%20Suk%20Ngo%20ft.pdf Chua, Suk Ngo (2011) Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma. Masters thesis, Faculty of Resources Science & Technology. |
| spellingShingle | RB Pathology Chua, Suk Ngo Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma |
| title | Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma |
| title_full | Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma |
| title_fullStr | Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma |
| title_full_unstemmed | Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma |
| title_short | Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma |
| title_sort | molecular study of selected differentially expressed genes in nasopharyngeal carcinoma |
| topic | RB Pathology |
| url | http://ir.unimas.my/id/eprint/13304/ http://ir.unimas.my/id/eprint/13304/2/Chua%20Suk%20Ngo%20ft.pdf |