Estimating Geographical Variation in the Risk of Zoonotic Plasmodium knowlesi Infection in Countries Eliminating Malaria
Plasmodium knowlesi is a malaria parasite found in wild monkey populations and transmitted from this animal reservoir to humans via infected mosquitoes. It causes severe and fatal disease in humans, and is the most common cause of malaria in parts of Malaysia. The geographical distribution of thi...
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| Format: | Article |
| Language: | English |
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PLOS
2016
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| Online Access: | http://ir.unimas.my/id/eprint/12860/ http://ir.unimas.my/id/eprint/12860/1/Estimating%20Geographical%20Variation%20in%20the%20Risk%20of%20Zoonotic%20%28abstract%29.pdf |
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| author | Shearer, Freya M. Zhi, Huang Weiss, Daniel J. Wiebe, Antoinette Gibson, Harry S. Battle, Katherine E. Pigott, David M. Brady, Oliver J. Chaturong, Putaporntip Somchai, Jongwutiwe Yee, Ling Lau Magnus, Manske Roberto, Amato Iqbal, R. F., Elyazar Indra, Vythilingam Samir, Bhatt Gething, Peter W. Balbir, Singh Nick, Golding Hay, Simon I. Moyes, Catherine L. |
| author_facet | Shearer, Freya M. Zhi, Huang Weiss, Daniel J. Wiebe, Antoinette Gibson, Harry S. Battle, Katherine E. Pigott, David M. Brady, Oliver J. Chaturong, Putaporntip Somchai, Jongwutiwe Yee, Ling Lau Magnus, Manske Roberto, Amato Iqbal, R. F., Elyazar Indra, Vythilingam Samir, Bhatt Gething, Peter W. Balbir, Singh Nick, Golding Hay, Simon I. Moyes, Catherine L. |
| author_sort | Shearer, Freya M. |
| building | UNIMAS Institutional Repository |
| collection | Online Access |
| description | Plasmodium knowlesi is a malaria parasite found in wild monkey populations and transmitted
from this animal reservoir to humans via infected mosquitoes. It causes severe and
fatal disease in humans, and is the most common cause of malaria in parts of Malaysia.
The geographical distribution of this disease is largely unknown because it is often misdiagnosed
as one of the human malarias. Human malaria parasites are primarily transmitted
between humans via mosquitoes and are not frequently transmitted from other animals to
humans. Many countries in Southeast Asia, where P. knowlesi infections have been
reported, are making progress towards eliminating the human malarias. Understanding
the geographical distribution of P. knowlesi is important for identifying areas where
malaria transmission will continue after the human malarias have been eliminated. In
locations that have high volumes of P. knowlesi infection data, we modelled patterns of
variation in the data linked to environmental predictors, and used this to estimate P. knowlesi
infection risk in locations where data is lacking. The resulting map represents an initial
evidence-base for identifying areas of human disease risk that should be prioritized for surveillance,
particularly in the context of malaria elimination in the region. |
| first_indexed | 2025-11-15T06:37:19Z |
| format | Article |
| id | unimas-12860 |
| institution | Universiti Malaysia Sarawak |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T06:37:19Z |
| publishDate | 2016 |
| publisher | PLOS |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | unimas-128602016-11-01T01:32:13Z http://ir.unimas.my/id/eprint/12860/ Estimating Geographical Variation in the Risk of Zoonotic Plasmodium knowlesi Infection in Countries Eliminating Malaria Shearer, Freya M. Zhi, Huang Weiss, Daniel J. Wiebe, Antoinette Gibson, Harry S. Battle, Katherine E. Pigott, David M. Brady, Oliver J. Chaturong, Putaporntip Somchai, Jongwutiwe Yee, Ling Lau Magnus, Manske Roberto, Amato Iqbal, R. F., Elyazar Indra, Vythilingam Samir, Bhatt Gething, Peter W. Balbir, Singh Nick, Golding Hay, Simon I. Moyes, Catherine L. R Medicine (General) Plasmodium knowlesi is a malaria parasite found in wild monkey populations and transmitted from this animal reservoir to humans via infected mosquitoes. It causes severe and fatal disease in humans, and is the most common cause of malaria in parts of Malaysia. The geographical distribution of this disease is largely unknown because it is often misdiagnosed as one of the human malarias. Human malaria parasites are primarily transmitted between humans via mosquitoes and are not frequently transmitted from other animals to humans. Many countries in Southeast Asia, where P. knowlesi infections have been reported, are making progress towards eliminating the human malarias. Understanding the geographical distribution of P. knowlesi is important for identifying areas where malaria transmission will continue after the human malarias have been eliminated. In locations that have high volumes of P. knowlesi infection data, we modelled patterns of variation in the data linked to environmental predictors, and used this to estimate P. knowlesi infection risk in locations where data is lacking. The resulting map represents an initial evidence-base for identifying areas of human disease risk that should be prioritized for surveillance, particularly in the context of malaria elimination in the region. PLOS 2016 Article PeerReviewed text en http://ir.unimas.my/id/eprint/12860/1/Estimating%20Geographical%20Variation%20in%20the%20Risk%20of%20Zoonotic%20%28abstract%29.pdf Shearer, Freya M. and Zhi, Huang and Weiss, Daniel J. and Wiebe, Antoinette and Gibson, Harry S. and Battle, Katherine E. and Pigott, David M. and Brady, Oliver J. and Chaturong, Putaporntip and Somchai, Jongwutiwe and Yee, Ling Lau and Magnus, Manske and Roberto, Amato and Iqbal, R. and F., Elyazar and Indra, Vythilingam and Samir, Bhatt and Gething, Peter W. and Balbir, Singh and Nick, Golding and Hay, Simon I. and Moyes, Catherine L. (2016) Estimating Geographical Variation in the Risk of Zoonotic Plasmodium knowlesi Infection in Countries Eliminating Malaria. PLOS Neglected Tropical Diseases, 10 (8). ISSN 1935-2727 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84988807873&partnerID=40&md5=f4c2fdbbdc0a43cfc12557945a1e0b2d doi:10.1371/journal.pntd.0004915 |
| spellingShingle | R Medicine (General) Shearer, Freya M. Zhi, Huang Weiss, Daniel J. Wiebe, Antoinette Gibson, Harry S. Battle, Katherine E. Pigott, David M. Brady, Oliver J. Chaturong, Putaporntip Somchai, Jongwutiwe Yee, Ling Lau Magnus, Manske Roberto, Amato Iqbal, R. F., Elyazar Indra, Vythilingam Samir, Bhatt Gething, Peter W. Balbir, Singh Nick, Golding Hay, Simon I. Moyes, Catherine L. Estimating Geographical Variation in the Risk of Zoonotic Plasmodium knowlesi Infection in Countries Eliminating Malaria |
| title | Estimating Geographical Variation in the Risk of Zoonotic Plasmodium knowlesi Infection in Countries Eliminating Malaria |
| title_full | Estimating Geographical Variation in the Risk of Zoonotic Plasmodium knowlesi Infection in Countries Eliminating Malaria |
| title_fullStr | Estimating Geographical Variation in the Risk of Zoonotic Plasmodium knowlesi Infection in Countries Eliminating Malaria |
| title_full_unstemmed | Estimating Geographical Variation in the Risk of Zoonotic Plasmodium knowlesi Infection in Countries Eliminating Malaria |
| title_short | Estimating Geographical Variation in the Risk of Zoonotic Plasmodium knowlesi Infection in Countries Eliminating Malaria |
| title_sort | estimating geographical variation in the risk of zoonotic plasmodium knowlesi infection in countries eliminating malaria |
| topic | R Medicine (General) |
| url | http://ir.unimas.my/id/eprint/12860/ http://ir.unimas.my/id/eprint/12860/ http://ir.unimas.my/id/eprint/12860/ http://ir.unimas.my/id/eprint/12860/1/Estimating%20Geographical%20Variation%20in%20the%20Risk%20of%20Zoonotic%20%28abstract%29.pdf |