Serological Prevalence of Leptospirosis among Rural Communities in the Rejang Basin, Sarawak, Malaysia

Leptospirosis is an important zoonotic disease globally and is endemic in Malaysia. A study was conducted in the Rejang basin of Sarawak from June 2011 to May 2013 to determine the seroprevalence of leptospirosis among the communities and dominant infecting Leptospira serovars. A total of 508 human...

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Main Authors: Suut, L., Mazlan, M.N.A., Arif, M.T., Yusoff, H., Abdul Rahim, N.-A., Safii, R., Suhaili, M.R.
Format: Article
Language:English
Published: Sage Publication 2016
Subjects:
Online Access:http://ir.unimas.my/id/eprint/12818/
http://ir.unimas.my/id/eprint/12818/1/Serological%20Prevalence%20-%20Copy.pdf
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author Suut, L.
Mazlan, M.N.A.
Arif, M.T.
Yusoff, H.
Abdul Rahim, N.-A.
Safii, R.
Suhaili, M.R.
author_facet Suut, L.
Mazlan, M.N.A.
Arif, M.T.
Yusoff, H.
Abdul Rahim, N.-A.
Safii, R.
Suhaili, M.R.
author_sort Suut, L.
building UNIMAS Institutional Repository
collection Online Access
description Leptospirosis is an important zoonotic disease globally and is endemic in Malaysia. A study was conducted in the Rejang basin of Sarawak from June 2011 to May 2013 to determine the seroprevalence of leptospirosis among the communities and dominant infecting Leptospira serovars. A total of 508 human sera were analyzed using ELISA and the microscopic agglutination test (MAT). The seroprevalence of leptospirosis in the study area was 37.4%, with the highest prevalence in Kapit division. More women were positive for leptospirosis (59.5%), and the mean age of seropositive individuals was 42.2 (SD = 18.7) years. Antibody titers between 1:50 and 1:1600 were reported, and serovars djasiman (22.1%), shermani (13.2%), and pomona (7.9%) predominated, with varied distribution between geographical locations. This study highlighted the endemicity and diversity of existing Leptospira serovars within the community. This information should be communicated to local health personnel and communities at risk, and rapid diagnostic capability should be made available to local health facilities.
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spelling unimas-128182023-08-21T06:36:51Z http://ir.unimas.my/id/eprint/12818/ Serological Prevalence of Leptospirosis among Rural Communities in the Rejang Basin, Sarawak, Malaysia Suut, L. Mazlan, M.N.A. Arif, M.T. Yusoff, H. Abdul Rahim, N.-A. Safii, R. Suhaili, M.R. RA Public aspects of medicine RA0421 Public health. Hygiene. Preventive Medicine Leptospirosis is an important zoonotic disease globally and is endemic in Malaysia. A study was conducted in the Rejang basin of Sarawak from June 2011 to May 2013 to determine the seroprevalence of leptospirosis among the communities and dominant infecting Leptospira serovars. A total of 508 human sera were analyzed using ELISA and the microscopic agglutination test (MAT). The seroprevalence of leptospirosis in the study area was 37.4%, with the highest prevalence in Kapit division. More women were positive for leptospirosis (59.5%), and the mean age of seropositive individuals was 42.2 (SD = 18.7) years. Antibody titers between 1:50 and 1:1600 were reported, and serovars djasiman (22.1%), shermani (13.2%), and pomona (7.9%) predominated, with varied distribution between geographical locations. This study highlighted the endemicity and diversity of existing Leptospira serovars within the community. This information should be communicated to local health personnel and communities at risk, and rapid diagnostic capability should be made available to local health facilities. Sage Publication 2016 Article PeerReviewed text en http://ir.unimas.my/id/eprint/12818/1/Serological%20Prevalence%20-%20Copy.pdf Suut, L. and Mazlan, M.N.A. and Arif, M.T. and Yusoff, H. and Abdul Rahim, N.-A. and Safii, R. and Suhaili, M.R. (2016) Serological Prevalence of Leptospirosis among Rural Communities in the Rejang Basin, Sarawak, Malaysia. Asia-Pacific Journal of Public Health, 28 (5). pp. 450-457. ISSN 1010-5395 https://www.scopus.com/record/display.uri?eid=2-s2.0-84976885372&origin=inward&txGid=0 DOI: 10.1177/1010539516648003
spellingShingle RA Public aspects of medicine
RA0421 Public health. Hygiene. Preventive Medicine
Suut, L.
Mazlan, M.N.A.
Arif, M.T.
Yusoff, H.
Abdul Rahim, N.-A.
Safii, R.
Suhaili, M.R.
Serological Prevalence of Leptospirosis among Rural Communities in the Rejang Basin, Sarawak, Malaysia
title Serological Prevalence of Leptospirosis among Rural Communities in the Rejang Basin, Sarawak, Malaysia
title_full Serological Prevalence of Leptospirosis among Rural Communities in the Rejang Basin, Sarawak, Malaysia
title_fullStr Serological Prevalence of Leptospirosis among Rural Communities in the Rejang Basin, Sarawak, Malaysia
title_full_unstemmed Serological Prevalence of Leptospirosis among Rural Communities in the Rejang Basin, Sarawak, Malaysia
title_short Serological Prevalence of Leptospirosis among Rural Communities in the Rejang Basin, Sarawak, Malaysia
title_sort serological prevalence of leptospirosis among rural communities in the rejang basin, sarawak, malaysia
topic RA Public aspects of medicine
RA0421 Public health. Hygiene. Preventive Medicine
url http://ir.unimas.my/id/eprint/12818/
http://ir.unimas.my/id/eprint/12818/
http://ir.unimas.my/id/eprint/12818/
http://ir.unimas.my/id/eprint/12818/1/Serological%20Prevalence%20-%20Copy.pdf