Cloning and expression analysis of abcb 1 gene in Rasbora sarawakensis

The ATP-binding Cassette (ABC) gene family constitutes one the most abundant gene families in encoding transport proteins. The genes in this family are highly conserved across a variety of species. This great degree of conservation indicates its important role in organisms, particularly in the trans...

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Bibliographic Details
Main Author: Zain Illyaaseen, bin Khairudin
Format: Final Year Project Report / IMRAD
Language:English
Published: Universiti Malaysia Sarawak, (UNIMAS) 2015
Subjects:
Online Access:http://ir.unimas.my/id/eprint/11403/
http://ir.unimas.my/id/eprint/11403/2/Zain%28fulltext%29.pdf
Description
Summary:The ATP-binding Cassette (ABC) gene family constitutes one the most abundant gene families in encoding transport proteins. The genes in this family are highly conserved across a variety of species. This great degree of conservation indicates its important role in organisms, particularly in the transport of substances across the plasma membrane. Mutations in genes of this critical superfamily can cause a wide range of genetic conditions which can cause neurological malfunctions and altered drug response