Synthesis, characterization and antibacterial activity of bis thiourea derivatives
A series of bisthiourea derivatives were succesfully synthesized by reaction of benzene-1, 4 dicarbonyl isothiocyanate intermediates and isophthaloyl dichloride, with a series of aromatic amine at ortho, meta and para position. The structure of synthesised compound characterized by infra-red spect...
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| Format: | Final Year Project Report / IMRAD |
| Language: | English |
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Universiti Malaysia Sarawak, (UNIMAS)
2015
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| Online Access: | http://ir.unimas.my/id/eprint/11053/ http://ir.unimas.my/id/eprint/11053/9/Synthesis%2C%20Characterization..%28fulltext%29.pdf |
| _version_ | 1848836923739602944 |
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| author | Jayakumar, Ponniasalan |
| author_facet | Jayakumar, Ponniasalan |
| author_sort | Jayakumar, Ponniasalan |
| building | UNIMAS Institutional Repository |
| collection | Online Access |
| description | A series of bisthiourea derivatives were succesfully synthesized by reaction of benzene-1, 4 dicarbonyl isothiocyanate intermediates and isophthaloyl dichloride, with a series of aromatic amine at ortho, meta and para position. The structure of synthesised compound characterized by infra-red spectroscopy (FTIR), 1H Nuclear magnetic resonances, and 13C Nuclear magnetic resonances. The synthesised compounds were screened for their antibacterial properties using Gram-negative bacteria Escherichia coli (E.coli) by using disc diffusion method. All of synthesized series showed negative results towards antibacterial activity. |
| first_indexed | 2025-11-15T06:31:29Z |
| format | Final Year Project Report / IMRAD |
| id | unimas-11053 |
| institution | Universiti Malaysia Sarawak |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T06:31:29Z |
| publishDate | 2015 |
| publisher | Universiti Malaysia Sarawak, (UNIMAS) |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | unimas-110532023-06-28T07:04:38Z http://ir.unimas.my/id/eprint/11053/ Synthesis, characterization and antibacterial activity of bis thiourea derivatives Jayakumar, Ponniasalan RV Botanic, Thomsonian, and eclectic medicine A series of bisthiourea derivatives were succesfully synthesized by reaction of benzene-1, 4 dicarbonyl isothiocyanate intermediates and isophthaloyl dichloride, with a series of aromatic amine at ortho, meta and para position. The structure of synthesised compound characterized by infra-red spectroscopy (FTIR), 1H Nuclear magnetic resonances, and 13C Nuclear magnetic resonances. The synthesised compounds were screened for their antibacterial properties using Gram-negative bacteria Escherichia coli (E.coli) by using disc diffusion method. All of synthesized series showed negative results towards antibacterial activity. Universiti Malaysia Sarawak, (UNIMAS) 2015 Final Year Project Report / IMRAD NonPeerReviewed text en http://ir.unimas.my/id/eprint/11053/9/Synthesis%2C%20Characterization..%28fulltext%29.pdf Jayakumar, Ponniasalan (2015) Synthesis, characterization and antibacterial activity of bis thiourea derivatives. [Final Year Project Report / IMRAD] (Unpublished) |
| spellingShingle | RV Botanic, Thomsonian, and eclectic medicine Jayakumar, Ponniasalan Synthesis, characterization and antibacterial activity of bis thiourea derivatives |
| title | Synthesis, characterization and antibacterial activity of bis thiourea derivatives |
| title_full | Synthesis, characterization and antibacterial activity of bis thiourea derivatives |
| title_fullStr | Synthesis, characterization and antibacterial activity of bis thiourea derivatives |
| title_full_unstemmed | Synthesis, characterization and antibacterial activity of bis thiourea derivatives |
| title_short | Synthesis, characterization and antibacterial activity of bis thiourea derivatives |
| title_sort | synthesis, characterization and antibacterial activity of bis thiourea derivatives |
| topic | RV Botanic, Thomsonian, and eclectic medicine |
| url | http://ir.unimas.my/id/eprint/11053/ http://ir.unimas.my/id/eprint/11053/9/Synthesis%2C%20Characterization..%28fulltext%29.pdf |