Production of Kojic Acid from Sago ‘Hampas’

Kojic acid is a depigmenting agent that has diverse industrial application particularly in cosmetics, food and health care industries. This research attempts to study production of kojic acid from sago ‘hampas’ via solid state fermentation (SSF) by using Aspergillus flavus Link 44-1 and Aspergillu...

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Main Author: Spencer Empading, Alvin Miai
Format: Thesis
Language:English
Published: 2015
Subjects:
Online Access:http://ir.unimas.my/id/eprint/10935/
http://ir.unimas.my/id/eprint/10935/1/Alvin%20Miai.pdf
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author Spencer Empading, Alvin Miai
author_facet Spencer Empading, Alvin Miai
author_sort Spencer Empading, Alvin Miai
building UNIMAS Institutional Repository
collection Online Access
description Kojic acid is a depigmenting agent that has diverse industrial application particularly in cosmetics, food and health care industries. This research attempts to study production of kojic acid from sago ‘hampas’ via solid state fermentation (SSF) by using Aspergillus flavus Link 44-1 and Aspergillus flavus NSH9 as the dual strain inoculant. In the preliminary studies of kojic acid production, a maximum yield of 3.651 g/L, 3.332 g/L, and 3.999 g/L was produced via SSF using A. flavus NSH9, A. flavus Link 44-1, and A mixture of both strains respectively. Optimization of cultural conditions for kojic acid was conducted using the Response Surface Methodology (RSM). The process parameters studied were initial moisture content (50-90%, v/w), inoculum size (5-35%, v/w), urea concentration (0.5-3.5%, v/w), mineral salts solution (5-35%, v/w), and incubation time (9-21 days). Optimization of kojic acid production was successful as the yield of kojic acid obtained was higher than the predicted value in the RSM. A maximum yield of 3.102 g/L, 2.745 g/L, and 3.102 g/L was produced via SSF using A. flavus NSH9, A. flavus Link 44-1, and A mixture of both strains respectively.
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spelling unimas-109352023-08-01T07:40:53Z http://ir.unimas.my/id/eprint/10935/ Production of Kojic Acid from Sago ‘Hampas’ Spencer Empading, Alvin Miai GE Environmental Sciences Q Science (General) Kojic acid is a depigmenting agent that has diverse industrial application particularly in cosmetics, food and health care industries. This research attempts to study production of kojic acid from sago ‘hampas’ via solid state fermentation (SSF) by using Aspergillus flavus Link 44-1 and Aspergillus flavus NSH9 as the dual strain inoculant. In the preliminary studies of kojic acid production, a maximum yield of 3.651 g/L, 3.332 g/L, and 3.999 g/L was produced via SSF using A. flavus NSH9, A. flavus Link 44-1, and A mixture of both strains respectively. Optimization of cultural conditions for kojic acid was conducted using the Response Surface Methodology (RSM). The process parameters studied were initial moisture content (50-90%, v/w), inoculum size (5-35%, v/w), urea concentration (0.5-3.5%, v/w), mineral salts solution (5-35%, v/w), and incubation time (9-21 days). Optimization of kojic acid production was successful as the yield of kojic acid obtained was higher than the predicted value in the RSM. A maximum yield of 3.102 g/L, 2.745 g/L, and 3.102 g/L was produced via SSF using A. flavus NSH9, A. flavus Link 44-1, and A mixture of both strains respectively. 2015 Thesis NonPeerReviewed text en http://ir.unimas.my/id/eprint/10935/1/Alvin%20Miai.pdf Spencer Empading, Alvin Miai (2015) Production of Kojic Acid from Sago ‘Hampas’. Masters thesis, Universiti Malaysia Sarawak, (UNIMAS).
spellingShingle GE Environmental Sciences
Q Science (General)
Spencer Empading, Alvin Miai
Production of Kojic Acid from Sago ‘Hampas’
title Production of Kojic Acid from Sago ‘Hampas’
title_full Production of Kojic Acid from Sago ‘Hampas’
title_fullStr Production of Kojic Acid from Sago ‘Hampas’
title_full_unstemmed Production of Kojic Acid from Sago ‘Hampas’
title_short Production of Kojic Acid from Sago ‘Hampas’
title_sort production of kojic acid from sago ‘hampas’
topic GE Environmental Sciences
Q Science (General)
url http://ir.unimas.my/id/eprint/10935/
http://ir.unimas.my/id/eprint/10935/1/Alvin%20Miai.pdf