Toxicity Screening of Dibenzothiophene on Early Vertebrate Development

Dibenzothiophene is a minor component of petroleum crudes, coal tars, shale oil and synthetic fuels which has a toxic property to mammals and aquatic verterbrates. This research was conducted to analyse the toxicity effects of dibenzothiophene on zebrafish (Danio rerio) embryos at every pre deter...

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Main Author: Memarshall, M. Ongkudon
Format: Final Year Project Report / IMRAD
Language:English
Published: Universiti Malaysia Sarawak, (UNIMAS) 2015
Subjects:
Online Access:http://ir.unimas.my/id/eprint/10770/
http://ir.unimas.my/id/eprint/10770/8/Toxicity%20Screening%20Dibenzothiophene%20on%20Early%20Vertebrate%20Development%20%28fulltext%29.pdf
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author Memarshall, M. Ongkudon
author_facet Memarshall, M. Ongkudon
author_sort Memarshall, M. Ongkudon
building UNIMAS Institutional Repository
collection Online Access
description Dibenzothiophene is a minor component of petroleum crudes, coal tars, shale oil and synthetic fuels which has a toxic property to mammals and aquatic verterbrates. This research was conducted to analyse the toxicity effects of dibenzothiophene on zebrafish (Danio rerio) embryos at every pre determined stage of its embryogenesis. Different concentration of dibenzothiophene was exposed to the embryos and several parameters (developmental effects) were chosen to be observed throughout the embryogenesis of D. rerio embryos. The results of this experiment shows that dibenzothiophene cause delay in D. rerio embryos morphogenesis. LCso ofdibenzothiophene for D. rerio embryo was also determined in this study by taking the average total mortality of the replicates which has nearest value to 50%. It was concluded that different concentrations of dibenzothiophene exert different severity ofdefects in D. rerio embryogenesis.
first_indexed 2025-11-15T06:30:24Z
format Final Year Project Report / IMRAD
id unimas-10770
institution Universiti Malaysia Sarawak
institution_category Local University
language English
last_indexed 2025-11-15T06:30:24Z
publishDate 2015
publisher Universiti Malaysia Sarawak, (UNIMAS)
recordtype eprints
repository_type Digital Repository
spelling unimas-107702023-08-18T08:36:51Z http://ir.unimas.my/id/eprint/10770/ Toxicity Screening of Dibenzothiophene on Early Vertebrate Development Memarshall, M. Ongkudon GE Environmental Sciences Dibenzothiophene is a minor component of petroleum crudes, coal tars, shale oil and synthetic fuels which has a toxic property to mammals and aquatic verterbrates. This research was conducted to analyse the toxicity effects of dibenzothiophene on zebrafish (Danio rerio) embryos at every pre determined stage of its embryogenesis. Different concentration of dibenzothiophene was exposed to the embryos and several parameters (developmental effects) were chosen to be observed throughout the embryogenesis of D. rerio embryos. The results of this experiment shows that dibenzothiophene cause delay in D. rerio embryos morphogenesis. LCso ofdibenzothiophene for D. rerio embryo was also determined in this study by taking the average total mortality of the replicates which has nearest value to 50%. It was concluded that different concentrations of dibenzothiophene exert different severity ofdefects in D. rerio embryogenesis. Universiti Malaysia Sarawak, (UNIMAS) 2015 Final Year Project Report / IMRAD NonPeerReviewed text en http://ir.unimas.my/id/eprint/10770/8/Toxicity%20Screening%20Dibenzothiophene%20on%20Early%20Vertebrate%20Development%20%28fulltext%29.pdf Memarshall, M. Ongkudon (2015) Toxicity Screening of Dibenzothiophene on Early Vertebrate Development. [Final Year Project Report / IMRAD] (Unpublished)
spellingShingle GE Environmental Sciences
Memarshall, M. Ongkudon
Toxicity Screening of Dibenzothiophene on Early Vertebrate Development
title Toxicity Screening of Dibenzothiophene on Early Vertebrate Development
title_full Toxicity Screening of Dibenzothiophene on Early Vertebrate Development
title_fullStr Toxicity Screening of Dibenzothiophene on Early Vertebrate Development
title_full_unstemmed Toxicity Screening of Dibenzothiophene on Early Vertebrate Development
title_short Toxicity Screening of Dibenzothiophene on Early Vertebrate Development
title_sort toxicity screening of dibenzothiophene on early vertebrate development
topic GE Environmental Sciences
url http://ir.unimas.my/id/eprint/10770/
http://ir.unimas.my/id/eprint/10770/8/Toxicity%20Screening%20Dibenzothiophene%20on%20Early%20Vertebrate%20Development%20%28fulltext%29.pdf