Risk Factors and Prediction Models for Retinopathy of Prematurity
Objectives: To develop a simple prediction model for the pre-screening of Retinopathy of Prematurity (ROP) among preterm babies. Methods: This was a prospective study. The test dataset (January 2007 until December 2010) was used to construct risk prediction models, and the validation dataset (Januar...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Universiti Sains Malaysia,
2015
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| Online Access: | http://ir.unimas.my/id/eprint/10727/ http://ir.unimas.my/id/eprint/10727/1/Mallika.pdf |
| _version_ | 1848836846679752704 |
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| author | Mallika, Premsenthil Tan, Aik Kah |
| author_facet | Mallika, Premsenthil Tan, Aik Kah |
| author_sort | Mallika, Premsenthil |
| building | UNIMAS Institutional Repository |
| collection | Online Access |
| description | Objectives: To develop a simple prediction model for the pre-screening of Retinopathy of Prematurity (ROP) among preterm babies. Methods: This was a prospective study. The test dataset (January 2007 until December 2010) was used to construct risk prediction models, and the validation dataset (January 2011 until March 2012) was used to validate the models developed from the test dataset. Two prediction models were produced using the test dataset based on logistic regression equations in which the development of
ROP was used as the outcome.
Results: The sensitivity and specificity for model 1 [gestational age (GA), birth weight (BW),
intraventricular haemorrhage (IVH) and respiratory distress syndrome (RDS)] was 82 % and
81.7%, respectively; for model 2, (GA and BW) the sensitivity and specificity were 80.5% and 80.3%,
respectively.
Conclusion: Model 2 was preferable, as it only required two predictors (GA and BW). Our
models can be used for the early prevention of ROP to avoid poor outcomes. |
| first_indexed | 2025-11-15T06:30:15Z |
| format | Article |
| id | unimas-10727 |
| institution | Universiti Malaysia Sarawak |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T06:30:15Z |
| publishDate | 2015 |
| publisher | Universiti Sains Malaysia, |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | unimas-107272022-01-28T02:10:39Z http://ir.unimas.my/id/eprint/10727/ Risk Factors and Prediction Models for Retinopathy of Prematurity Mallika, Premsenthil Tan, Aik Kah R Medicine (General) Objectives: To develop a simple prediction model for the pre-screening of Retinopathy of Prematurity (ROP) among preterm babies. Methods: This was a prospective study. The test dataset (January 2007 until December 2010) was used to construct risk prediction models, and the validation dataset (January 2011 until March 2012) was used to validate the models developed from the test dataset. Two prediction models were produced using the test dataset based on logistic regression equations in which the development of ROP was used as the outcome. Results: The sensitivity and specificity for model 1 [gestational age (GA), birth weight (BW), intraventricular haemorrhage (IVH) and respiratory distress syndrome (RDS)] was 82 % and 81.7%, respectively; for model 2, (GA and BW) the sensitivity and specificity were 80.5% and 80.3%, respectively. Conclusion: Model 2 was preferable, as it only required two predictors (GA and BW). Our models can be used for the early prevention of ROP to avoid poor outcomes. Universiti Sains Malaysia, 2015 Article PeerReviewed text en http://ir.unimas.my/id/eprint/10727/1/Mallika.pdf Mallika, Premsenthil and Tan, Aik Kah (2015) Risk Factors and Prediction Models for Retinopathy of Prematurity. Malaysian Journal Medical Science, 22 (5). pp. 57-63. ISSN 2180-4303 http://www.scopus.com/inward/record.url?eid=2-s2.0-84940741067&partnerID=40&md5=3eab0f6f1b5953e4d15e86cfff543a93 |
| spellingShingle | R Medicine (General) Mallika, Premsenthil Tan, Aik Kah Risk Factors and Prediction Models for Retinopathy of Prematurity |
| title | Risk Factors and Prediction Models for Retinopathy of Prematurity |
| title_full | Risk Factors and Prediction Models for Retinopathy of Prematurity |
| title_fullStr | Risk Factors and Prediction Models for Retinopathy of Prematurity |
| title_full_unstemmed | Risk Factors and Prediction Models for Retinopathy of Prematurity |
| title_short | Risk Factors and Prediction Models for Retinopathy of Prematurity |
| title_sort | risk factors and prediction models for retinopathy of prematurity |
| topic | R Medicine (General) |
| url | http://ir.unimas.my/id/eprint/10727/ http://ir.unimas.my/id/eprint/10727/ http://ir.unimas.my/id/eprint/10727/1/Mallika.pdf |