Effects of dual impeller system of Rushton turbine, concave disk turbine and their combinations on the performance of kojic acid fermentation by Aspergillus flavus Link 44-1

In the present work, the effects of dual impeller configurations comprising of Rushton turbine (RT) and Concave-bladed disk turbine (CD-6) on the oxygen transfer profile and fermentation performance of kojic acid production by Aspergillus flavus Link 44-1 was investigated. Batch cultivations of A....

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Main Authors: Nurashikin, Suhaili, Tan, Joo Shun, Mohd-Shamzi, Mohamed, Murni, Halim, A.B., Ariff
Format: Article
Language:English
Published: Wiley Online Library 2015
Subjects:
Online Access:http://ir.unimas.my/id/eprint/10588/
http://ir.unimas.my/id/eprint/10588/1/NO%2042%20Effects%20of%20dual%20impeller%20system%20of%20Rushton%20turbine%2C%20concave%20disk%20turbine%20and%20their%20combinations%20on%20the%20performance%20of%20kojic%20acid%20fermentation%20by%20Aspergillus%20flavus%20Link%2044-1%20%28abstract%29.pdf
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author Nurashikin, Suhaili
Tan, Joo Shun
Mohd-Shamzi, Mohamed
Murni, Halim
A.B., Ariff
author_facet Nurashikin, Suhaili
Tan, Joo Shun
Mohd-Shamzi, Mohamed
Murni, Halim
A.B., Ariff
author_sort Nurashikin, Suhaili
building UNIMAS Institutional Repository
collection Online Access
description In the present work, the effects of dual impeller configurations comprising of Rushton turbine (RT) and Concave-bladed disk turbine (CD-6) on the oxygen transfer profile and fermentation performance of kojic acid production by Aspergillus flavus Link 44-1 was investigated. Batch cultivations of A. flavus Link 44-1 were performed in 2 L stirred tank bioreactor. The fermentations were conducted using different dual impeller systems; (1) RT-RT, (2) CD6-CD6, (3) RT-CD6, and (4) CD6-RT (bottom-top impeller). It was perceived that dual CD-6 system was able to improve oxygen transfer rate by about 25–45% over the hybrids of RT and CD-6 and the typically configured dual RT system. While no substantial disparity could be seen on the fungal growth rate by the manipulation of the impeller, high concentration of kojic acid (44.93 g L�1) was attained with the use of dual CD-6 as the mixer. Efficient agitating system that can facilitate good gas dispersion capability is crucially required in order to counteract the problem of oxygen solubility limitation faced in such viscous fungal fermentation broth. The results from this work suggested the promising capability of dual CD-6 configuration in enhancing productivity of kojic acid fermentation in stirred tank bioreactor.
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institution Universiti Malaysia Sarawak
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language English
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publishDate 2015
publisher Wiley Online Library
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spelling unimas-105882023-03-29T06:46:06Z http://ir.unimas.my/id/eprint/10588/ Effects of dual impeller system of Rushton turbine, concave disk turbine and their combinations on the performance of kojic acid fermentation by Aspergillus flavus Link 44-1 Nurashikin, Suhaili Tan, Joo Shun Mohd-Shamzi, Mohamed Murni, Halim A.B., Ariff TP Chemical technology In the present work, the effects of dual impeller configurations comprising of Rushton turbine (RT) and Concave-bladed disk turbine (CD-6) on the oxygen transfer profile and fermentation performance of kojic acid production by Aspergillus flavus Link 44-1 was investigated. Batch cultivations of A. flavus Link 44-1 were performed in 2 L stirred tank bioreactor. The fermentations were conducted using different dual impeller systems; (1) RT-RT, (2) CD6-CD6, (3) RT-CD6, and (4) CD6-RT (bottom-top impeller). It was perceived that dual CD-6 system was able to improve oxygen transfer rate by about 25–45% over the hybrids of RT and CD-6 and the typically configured dual RT system. While no substantial disparity could be seen on the fungal growth rate by the manipulation of the impeller, high concentration of kojic acid (44.93 g L�1) was attained with the use of dual CD-6 as the mixer. Efficient agitating system that can facilitate good gas dispersion capability is crucially required in order to counteract the problem of oxygen solubility limitation faced in such viscous fungal fermentation broth. The results from this work suggested the promising capability of dual CD-6 configuration in enhancing productivity of kojic acid fermentation in stirred tank bioreactor. Wiley Online Library 2015 Article PeerReviewed text en http://ir.unimas.my/id/eprint/10588/1/NO%2042%20Effects%20of%20dual%20impeller%20system%20of%20Rushton%20turbine%2C%20concave%20disk%20turbine%20and%20their%20combinations%20on%20the%20performance%20of%20kojic%20acid%20fermentation%20by%20Aspergillus%20flavus%20Link%2044-1%20%28abstract%29.pdf Nurashikin, Suhaili and Tan, Joo Shun and Mohd-Shamzi, Mohamed and Murni, Halim and A.B., Ariff (2015) Effects of dual impeller system of Rushton turbine, concave disk turbine and their combinations on the performance of kojic acid fermentation by Aspergillus flavus Link 44-1. Asia-Pacific Journal Of Chemical Engineering, 10 (1). pp. 65-74. ISSN 1932-2143 http://onlinelibrary.wiley.com/doi/10.1002/apj.1846/abstract DOI: 10.1002/apj.1846
spellingShingle TP Chemical technology
Nurashikin, Suhaili
Tan, Joo Shun
Mohd-Shamzi, Mohamed
Murni, Halim
A.B., Ariff
Effects of dual impeller system of Rushton turbine, concave disk turbine and their combinations on the performance of kojic acid fermentation by Aspergillus flavus Link 44-1
title Effects of dual impeller system of Rushton turbine, concave disk turbine and their combinations on the performance of kojic acid fermentation by Aspergillus flavus Link 44-1
title_full Effects of dual impeller system of Rushton turbine, concave disk turbine and their combinations on the performance of kojic acid fermentation by Aspergillus flavus Link 44-1
title_fullStr Effects of dual impeller system of Rushton turbine, concave disk turbine and their combinations on the performance of kojic acid fermentation by Aspergillus flavus Link 44-1
title_full_unstemmed Effects of dual impeller system of Rushton turbine, concave disk turbine and their combinations on the performance of kojic acid fermentation by Aspergillus flavus Link 44-1
title_short Effects of dual impeller system of Rushton turbine, concave disk turbine and their combinations on the performance of kojic acid fermentation by Aspergillus flavus Link 44-1
title_sort effects of dual impeller system of rushton turbine, concave disk turbine and their combinations on the performance of kojic acid fermentation by aspergillus flavus link 44-1
topic TP Chemical technology
url http://ir.unimas.my/id/eprint/10588/
http://ir.unimas.my/id/eprint/10588/
http://ir.unimas.my/id/eprint/10588/
http://ir.unimas.my/id/eprint/10588/1/NO%2042%20Effects%20of%20dual%20impeller%20system%20of%20Rushton%20turbine%2C%20concave%20disk%20turbine%20and%20their%20combinations%20on%20the%20performance%20of%20kojic%20acid%20fermentation%20by%20Aspergillus%20flavus%20Link%2044-1%20%28abstract%29.pdf