Transformation of Chitinase in Yeast Pichia Pastoris GS115

Chitinases are enzyme that degrades chitin, the second most abundant polysaccharide after cellulose. Chitin is found in the exoskeleton of many organisms including insects, fungi, yeast and algae. It is also has been found in the internal structures of other vertebrates. Chitin and the chitinolyti...

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Main Author: Rasyidah, binti Ramlee
Format: Final Year Project Report / IMRAD
Language:English
English
Published: Universiti Malaysia Sarawak, (UNIMAS) 2015
Subjects:
Online Access:http://ir.unimas.my/id/eprint/10426/
http://ir.unimas.my/id/eprint/10426/1/Transformation%20of%20Chitinase%20in%20Yeast%20Pichia%20Pastoris%20GS115%20%2824pgs%29.pdf
http://ir.unimas.my/id/eprint/10426/8/Rafidah%20Rahman%20ft.pdf
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author Rasyidah, binti Ramlee
author_facet Rasyidah, binti Ramlee
author_sort Rasyidah, binti Ramlee
building UNIMAS Institutional Repository
collection Online Access
description Chitinases are enzyme that degrades chitin, the second most abundant polysaccharide after cellulose. Chitin is found in the exoskeleton of many organisms including insects, fungi, yeast and algae. It is also has been found in the internal structures of other vertebrates. Chitin and the chitinolytic enzymes are very useful for their applications in biotechnology sector. Chitinase contribute in human health care especially in human disease like asthma. Chitinases also have a wide-range application in preparation of pharmaceutically important chitooligosaccharides and N-acetylglucosamin. Transformation of chitinase gene in yeast Pichia pastoris GS115 was performed via EasyCompTM transformation. Chitinase gene extracted from Metroxylan sagu and has been constructed in pPICZαC was used in this project. The confirmation of insertion in the positive transformant that contain pPICZαC/Chitinase vector was done via colony PCR.
first_indexed 2025-11-15T06:29:11Z
format Final Year Project Report / IMRAD
id unimas-10426
institution Universiti Malaysia Sarawak
institution_category Local University
language English
English
last_indexed 2025-11-15T06:29:11Z
publishDate 2015
publisher Universiti Malaysia Sarawak, (UNIMAS)
recordtype eprints
repository_type Digital Repository
spelling unimas-104262024-03-13T05:49:50Z http://ir.unimas.my/id/eprint/10426/ Transformation of Chitinase in Yeast Pichia Pastoris GS115 Rasyidah, binti Ramlee QR Microbiology Chitinases are enzyme that degrades chitin, the second most abundant polysaccharide after cellulose. Chitin is found in the exoskeleton of many organisms including insects, fungi, yeast and algae. It is also has been found in the internal structures of other vertebrates. Chitin and the chitinolytic enzymes are very useful for their applications in biotechnology sector. Chitinase contribute in human health care especially in human disease like asthma. Chitinases also have a wide-range application in preparation of pharmaceutically important chitooligosaccharides and N-acetylglucosamin. Transformation of chitinase gene in yeast Pichia pastoris GS115 was performed via EasyCompTM transformation. Chitinase gene extracted from Metroxylan sagu and has been constructed in pPICZαC was used in this project. The confirmation of insertion in the positive transformant that contain pPICZαC/Chitinase vector was done via colony PCR. Universiti Malaysia Sarawak, (UNIMAS) 2015 Final Year Project Report / IMRAD NonPeerReviewed text en http://ir.unimas.my/id/eprint/10426/1/Transformation%20of%20Chitinase%20in%20Yeast%20Pichia%20Pastoris%20GS115%20%2824pgs%29.pdf text en http://ir.unimas.my/id/eprint/10426/8/Rafidah%20Rahman%20ft.pdf Rasyidah, binti Ramlee (2015) Transformation of Chitinase in Yeast Pichia Pastoris GS115. [Final Year Project Report / IMRAD]
spellingShingle QR Microbiology
Rasyidah, binti Ramlee
Transformation of Chitinase in Yeast Pichia Pastoris GS115
title Transformation of Chitinase in Yeast Pichia Pastoris GS115
title_full Transformation of Chitinase in Yeast Pichia Pastoris GS115
title_fullStr Transformation of Chitinase in Yeast Pichia Pastoris GS115
title_full_unstemmed Transformation of Chitinase in Yeast Pichia Pastoris GS115
title_short Transformation of Chitinase in Yeast Pichia Pastoris GS115
title_sort transformation of chitinase in yeast pichia pastoris gs115
topic QR Microbiology
url http://ir.unimas.my/id/eprint/10426/
http://ir.unimas.my/id/eprint/10426/1/Transformation%20of%20Chitinase%20in%20Yeast%20Pichia%20Pastoris%20GS115%20%2824pgs%29.pdf
http://ir.unimas.my/id/eprint/10426/8/Rafidah%20Rahman%20ft.pdf