Proteins are Potent Biomarkers to Detect Colon Cancer Progression

Colon cancer is the most common type of cancer and major cause of death worldwide. The detection of colon cancer is difficult in early stages. However, the secretory proteins have been used as ideal biomarker for the detection of colon cancer progress in cancer patients. Serum/tissue protein express...

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Main Authors: Kuppusamy, Palaniselvam, Natanamurugaraj, Govindan, M. M., Yusoff, J. A. Ichwan, Solachuddin
Format: Article
Language:English
Published: Elsevier 2017
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/8159/
http://umpir.ump.edu.my/id/eprint/8159/1/Proteins_are_potent_biomarkers_to_detect_colon_cancer_progression.pdf
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author Kuppusamy, Palaniselvam
Natanamurugaraj, Govindan
M. M., Yusoff
J. A. Ichwan, Solachuddin
author_facet Kuppusamy, Palaniselvam
Natanamurugaraj, Govindan
M. M., Yusoff
J. A. Ichwan, Solachuddin
author_sort Kuppusamy, Palaniselvam
building UMP Institutional Repository
collection Online Access
description Colon cancer is the most common type of cancer and major cause of death worldwide. The detection of colon cancer is difficult in early stages. However, the secretory proteins have been used as ideal biomarker for the detection of colon cancer progress in cancer patients. Serum/tissue protein expression could help general practitioners to identify colon cancer at earlier stages. By this way, we use the biomarkers to evaluate the anticancer drugs and their response to therapy in cancer models. Recently, the biomarker discovery is important in cancer biology and disease management. Also, many measurable specific molecular components have been studied in colon cancer therapeutics. The biomolecules are mainly DNA, RNA, metabolites, enzymes, mRNA, aptamers and proteins. Thus, in this review we demonstrate the important protein biomarker in colon cancer development and molecular identification of protein biomarker discovery.
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spelling ump-81592018-08-28T08:23:36Z http://umpir.ump.edu.my/id/eprint/8159/ Proteins are Potent Biomarkers to Detect Colon Cancer Progression Kuppusamy, Palaniselvam Natanamurugaraj, Govindan M. M., Yusoff J. A. Ichwan, Solachuddin Q Science (General) RC0254 Neoplasms. Tumors. Oncology (including Cancer) Colon cancer is the most common type of cancer and major cause of death worldwide. The detection of colon cancer is difficult in early stages. However, the secretory proteins have been used as ideal biomarker for the detection of colon cancer progress in cancer patients. Serum/tissue protein expression could help general practitioners to identify colon cancer at earlier stages. By this way, we use the biomarkers to evaluate the anticancer drugs and their response to therapy in cancer models. Recently, the biomarker discovery is important in cancer biology and disease management. Also, many measurable specific molecular components have been studied in colon cancer therapeutics. The biomolecules are mainly DNA, RNA, metabolites, enzymes, mRNA, aptamers and proteins. Thus, in this review we demonstrate the important protein biomarker in colon cancer development and molecular identification of protein biomarker discovery. Elsevier 2017-10-05 Article PeerReviewed application/pdf en cc_by_nc_nd http://umpir.ump.edu.my/id/eprint/8159/1/Proteins_are_potent_biomarkers_to_detect_colon_cancer_progression.pdf Kuppusamy, Palaniselvam and Natanamurugaraj, Govindan and M. M., Yusoff and J. A. Ichwan, Solachuddin (2017) Proteins are Potent Biomarkers to Detect Colon Cancer Progression. Saudi Journal of Biological Sciences. ISSN 1319-562X. (Published) http://dx.doi.org/10.1016/j.sjbs.2014.09.017
spellingShingle Q Science (General)
RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Kuppusamy, Palaniselvam
Natanamurugaraj, Govindan
M. M., Yusoff
J. A. Ichwan, Solachuddin
Proteins are Potent Biomarkers to Detect Colon Cancer Progression
title Proteins are Potent Biomarkers to Detect Colon Cancer Progression
title_full Proteins are Potent Biomarkers to Detect Colon Cancer Progression
title_fullStr Proteins are Potent Biomarkers to Detect Colon Cancer Progression
title_full_unstemmed Proteins are Potent Biomarkers to Detect Colon Cancer Progression
title_short Proteins are Potent Biomarkers to Detect Colon Cancer Progression
title_sort proteins are potent biomarkers to detect colon cancer progression
topic Q Science (General)
RC0254 Neoplasms. Tumors. Oncology (including Cancer)
url http://umpir.ump.edu.my/id/eprint/8159/
http://umpir.ump.edu.my/id/eprint/8159/
http://umpir.ump.edu.my/id/eprint/8159/1/Proteins_are_potent_biomarkers_to_detect_colon_cancer_progression.pdf