Optimal C:N ratio for the production of red pigments by Monascus ruber
The carbon-to-nitrogen (C:N) ratio in the biomass of microfungi tends to be quite different (e.g. 10–15) compared with the C:N ratio in the red pigments (e.g.[20) of the fungus Monascus ruber. Therefore, determining an optimal C:N ratio in the culture medium for maximizing the production of the...
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| Language: | English |
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Springer Netherlands
2014
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| Online Access: | http://umpir.ump.edu.my/id/eprint/8089/ http://umpir.ump.edu.my/id/eprint/8089/1/Optimal%20CN%20ratio%20for%20the%20production.pdf |
| _version_ | 1848818161924702208 |
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| author | M. Said, Farhan Brooks, John Chisti, Yusuf |
| author_facet | M. Said, Farhan Brooks, John Chisti, Yusuf |
| author_sort | M. Said, Farhan |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | The carbon-to-nitrogen (C:N) ratio in the biomass of microfungi tends to be quite different (e.g. 10–15)
compared with the C:N ratio in the red pigments (e.g.[20)
of the fungus Monascus ruber. Therefore, determining an
optimal C:N ratio in the culture medium for maximizing
the production of the pigments is important. A culture
medium composition is established for maximizing the
production of the red pigment by the fungus M. ruber
ICMP 15220 in submerged culture. The highest volumetric
productivity of the red pigment was 0.023 AU L-1 h-1 in
a batch culture (30 C, initial pH of 6.5) with a defined
medium of the following composition (g L-1): glucose
(10), monosodium glutamate (MSG) (10), MgSO47H2O (0.5), KH2PO4 (5), K2HPO4 (5), ZnSO47H2O (0.01),FeSO47H2O (0.01), CaCl2 (0.1), MnSO4H2O (0.03). This medium formulation had a C:N mole ratio of 9:1. Under these conditions, the specific growth rate of the fungus was 0.043 h-1 and the peak biomass concentration was 6.7 g L-1 in a 7-day culture. The biomass specific productivity of the red pigment was 1.06 AU g-1 h-1. The best nitrogen source proved to be MSG although four other inorganic nitrogen sources were evaluated. |
| first_indexed | 2025-11-15T01:33:16Z |
| format | Article |
| id | ump-8089 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T01:33:16Z |
| publishDate | 2014 |
| publisher | Springer Netherlands |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-80892018-04-04T05:48:34Z http://umpir.ump.edu.my/id/eprint/8089/ Optimal C:N ratio for the production of red pigments by Monascus ruber M. Said, Farhan Brooks, John Chisti, Yusuf TP Chemical technology The carbon-to-nitrogen (C:N) ratio in the biomass of microfungi tends to be quite different (e.g. 10–15) compared with the C:N ratio in the red pigments (e.g.[20) of the fungus Monascus ruber. Therefore, determining an optimal C:N ratio in the culture medium for maximizing the production of the pigments is important. A culture medium composition is established for maximizing the production of the red pigment by the fungus M. ruber ICMP 15220 in submerged culture. The highest volumetric productivity of the red pigment was 0.023 AU L-1 h-1 in a batch culture (30 C, initial pH of 6.5) with a defined medium of the following composition (g L-1): glucose (10), monosodium glutamate (MSG) (10), MgSO47H2O (0.5), KH2PO4 (5), K2HPO4 (5), ZnSO47H2O (0.01),FeSO47H2O (0.01), CaCl2 (0.1), MnSO4H2O (0.03). This medium formulation had a C:N mole ratio of 9:1. Under these conditions, the specific growth rate of the fungus was 0.043 h-1 and the peak biomass concentration was 6.7 g L-1 in a 7-day culture. The biomass specific productivity of the red pigment was 1.06 AU g-1 h-1. The best nitrogen source proved to be MSG although four other inorganic nitrogen sources were evaluated. Springer Netherlands 2014-05 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/8089/1/Optimal%20CN%20ratio%20for%20the%20production.pdf M. Said, Farhan and Brooks, John and Chisti, Yusuf (2014) Optimal C:N ratio for the production of red pigments by Monascus ruber. World Journal of Microbiology and Biotechnology, 30 (9). pp. 2471-2479. ISSN 0959-3993. (Published) https://doi.org/10.1007/s11274-014-1672-6 doi: 10.1007/s11274-014-1672-6 |
| spellingShingle | TP Chemical technology M. Said, Farhan Brooks, John Chisti, Yusuf Optimal C:N ratio for the production of red pigments by Monascus ruber |
| title | Optimal C:N ratio for the production of red pigments by Monascus ruber |
| title_full | Optimal C:N ratio for the production of red pigments by Monascus ruber |
| title_fullStr | Optimal C:N ratio for the production of red pigments by Monascus ruber |
| title_full_unstemmed | Optimal C:N ratio for the production of red pigments by Monascus ruber |
| title_short | Optimal C:N ratio for the production of red pigments by Monascus ruber |
| title_sort | optimal c:n ratio for the production of red pigments by monascus ruber |
| topic | TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/8089/ http://umpir.ump.edu.my/id/eprint/8089/ http://umpir.ump.edu.my/id/eprint/8089/ http://umpir.ump.edu.my/id/eprint/8089/1/Optimal%20CN%20ratio%20for%20the%20production.pdf |