Process Optimization of L-Phenylalanine onto Porous Silica Nanoparticles

Porous silica nanoparticles play an important role in the field of bioseparations and biomedical applications by offering large surface area and pore volume for adsorption of solutes. The present work deals with the synthesis, characterization and adsorption studies on silica nanoparticles. The nan...

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Main Authors: Tan, Suat Hian, Nurul Ain, Ismail
Format: Article
Language:English
Published: Trans Tech Publications 2014
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/6711/
http://umpir.ump.edu.my/id/eprint/6711/1/Process_Optimization_of_L-Phenylalanine_onto_Porous_Silica_Nanoparticles.PDF
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author Tan, Suat Hian
Nurul Ain, Ismail
author_facet Tan, Suat Hian
Nurul Ain, Ismail
author_sort Tan, Suat Hian
building UMP Institutional Repository
collection Online Access
description Porous silica nanoparticles play an important role in the field of bioseparations and biomedical applications by offering large surface area and pore volume for adsorption of solutes. The present work deals with the synthesis, characterization and adsorption studies on silica nanoparticles. The nanoparticles were synthesized using tetraethylorthosilicate as starting material and ethanol as solvent by sol-gel method under basic medium. Subsequently, L-phenylalanine was loaded into these nanoparticles by simple adsorption and the adsorption capacity was examined by UV spectrophotometer at 257 nm. The different operating parameters such as pH, silica nanoparticles dosage and duration on the uptake of the L-phenylalanine were studied. The results indicate the potential for a new use of silica nanoparticles as an effective adsorbent for Lphenylalanine.
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spelling ump-67112018-06-29T08:42:22Z http://umpir.ump.edu.my/id/eprint/6711/ Process Optimization of L-Phenylalanine onto Porous Silica Nanoparticles Tan, Suat Hian Nurul Ain, Ismail Q Science (General) QD Chemistry Porous silica nanoparticles play an important role in the field of bioseparations and biomedical applications by offering large surface area and pore volume for adsorption of solutes. The present work deals with the synthesis, characterization and adsorption studies on silica nanoparticles. The nanoparticles were synthesized using tetraethylorthosilicate as starting material and ethanol as solvent by sol-gel method under basic medium. Subsequently, L-phenylalanine was loaded into these nanoparticles by simple adsorption and the adsorption capacity was examined by UV spectrophotometer at 257 nm. The different operating parameters such as pH, silica nanoparticles dosage and duration on the uptake of the L-phenylalanine were studied. The results indicate the potential for a new use of silica nanoparticles as an effective adsorbent for Lphenylalanine. Trans Tech Publications 2014 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/6711/1/Process_Optimization_of_L-Phenylalanine_onto_Porous_Silica_Nanoparticles.PDF Tan, Suat Hian and Nurul Ain, Ismail (2014) Process Optimization of L-Phenylalanine onto Porous Silica Nanoparticles. Applied Mechanics and Materials, 563. pp. 90-93. ISSN 1662-7482. (Published) http://www.scientific.net/AMM.563.90 DOI: 10.4028/www.scientific.net/AMM.563.90
spellingShingle Q Science (General)
QD Chemistry
Tan, Suat Hian
Nurul Ain, Ismail
Process Optimization of L-Phenylalanine onto Porous Silica Nanoparticles
title Process Optimization of L-Phenylalanine onto Porous Silica Nanoparticles
title_full Process Optimization of L-Phenylalanine onto Porous Silica Nanoparticles
title_fullStr Process Optimization of L-Phenylalanine onto Porous Silica Nanoparticles
title_full_unstemmed Process Optimization of L-Phenylalanine onto Porous Silica Nanoparticles
title_short Process Optimization of L-Phenylalanine onto Porous Silica Nanoparticles
title_sort process optimization of l-phenylalanine onto porous silica nanoparticles
topic Q Science (General)
QD Chemistry
url http://umpir.ump.edu.my/id/eprint/6711/
http://umpir.ump.edu.my/id/eprint/6711/
http://umpir.ump.edu.my/id/eprint/6711/
http://umpir.ump.edu.my/id/eprint/6711/1/Process_Optimization_of_L-Phenylalanine_onto_Porous_Silica_Nanoparticles.PDF