Effects of Payena dasyphylla (Miq.) on Hyaluronidase Enzyme Activity and Metalloproteinases Protein Expressions in Interleukin-1β Stimulated Human Chondrocytes Cells

Hyaluronidases have been found as the target enzymes in the development of osteoarthritis (OA) disease. While there is still no curative treatment for this disease, recent studies on the treatment of OA were focused on the effectiveness of natural products which are expected to improve the symptoms...

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Main Authors: Kamini, Citalingam, Seema, Zareen, Khozirah, Shaari, Syahida, Ahmad
Format: Article
Language:English
Published: BioMed Central Ltd. 2013
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/6647/
http://umpir.ump.edu.my/id/eprint/6647/3/Effects%20of%20Payena%20dasyphylla%20%28Miq.%29%20on%20Hyaluronidase%20Enzyme%20Activity%20and%20Metalloproteinases%20Protein.pdf
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author Kamini, Citalingam
Seema, Zareen
Khozirah, Shaari
Syahida, Ahmad
author_facet Kamini, Citalingam
Seema, Zareen
Khozirah, Shaari
Syahida, Ahmad
author_sort Kamini, Citalingam
building UMP Institutional Repository
collection Online Access
description Hyaluronidases have been found as the target enzymes in the development of osteoarthritis (OA) disease. While there is still no curative treatment for this disease, recent studies on the treatment of OA were focused on the effectiveness of natural products which are expected to improve the symptoms with minimal side effects. The aim of this study was to screen selected Malaysian plants on their anti-hyaluronidase activity as well as to evaluate the active plant and its derived fractions on its potential anti-arthritic and antioxidant activities.
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publishDate 2013
publisher BioMed Central Ltd.
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spelling ump-66472018-04-26T02:03:14Z http://umpir.ump.edu.my/id/eprint/6647/ Effects of Payena dasyphylla (Miq.) on Hyaluronidase Enzyme Activity and Metalloproteinases Protein Expressions in Interleukin-1β Stimulated Human Chondrocytes Cells Kamini, Citalingam Seema, Zareen Khozirah, Shaari Syahida, Ahmad Q Science (General) Hyaluronidases have been found as the target enzymes in the development of osteoarthritis (OA) disease. While there is still no curative treatment for this disease, recent studies on the treatment of OA were focused on the effectiveness of natural products which are expected to improve the symptoms with minimal side effects. The aim of this study was to screen selected Malaysian plants on their anti-hyaluronidase activity as well as to evaluate the active plant and its derived fractions on its potential anti-arthritic and antioxidant activities. BioMed Central Ltd. 2013 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/6647/3/Effects%20of%20Payena%20dasyphylla%20%28Miq.%29%20on%20Hyaluronidase%20Enzyme%20Activity%20and%20Metalloproteinases%20Protein.pdf Kamini, Citalingam and Seema, Zareen and Khozirah, Shaari and Syahida, Ahmad (2013) Effects of Payena dasyphylla (Miq.) on Hyaluronidase Enzyme Activity and Metalloproteinases Protein Expressions in Interleukin-1β Stimulated Human Chondrocytes Cells. BMC Complementary and Alternative Medicine, 13 (213). pp. 1-12. ISSN 1472-6882. (Published) http://dx.doi.org/10.1186/1472-6882-13-213 DOI: 10.1186/1472-6882-13-213
spellingShingle Q Science (General)
Kamini, Citalingam
Seema, Zareen
Khozirah, Shaari
Syahida, Ahmad
Effects of Payena dasyphylla (Miq.) on Hyaluronidase Enzyme Activity and Metalloproteinases Protein Expressions in Interleukin-1β Stimulated Human Chondrocytes Cells
title Effects of Payena dasyphylla (Miq.) on Hyaluronidase Enzyme Activity and Metalloproteinases Protein Expressions in Interleukin-1β Stimulated Human Chondrocytes Cells
title_full Effects of Payena dasyphylla (Miq.) on Hyaluronidase Enzyme Activity and Metalloproteinases Protein Expressions in Interleukin-1β Stimulated Human Chondrocytes Cells
title_fullStr Effects of Payena dasyphylla (Miq.) on Hyaluronidase Enzyme Activity and Metalloproteinases Protein Expressions in Interleukin-1β Stimulated Human Chondrocytes Cells
title_full_unstemmed Effects of Payena dasyphylla (Miq.) on Hyaluronidase Enzyme Activity and Metalloproteinases Protein Expressions in Interleukin-1β Stimulated Human Chondrocytes Cells
title_short Effects of Payena dasyphylla (Miq.) on Hyaluronidase Enzyme Activity and Metalloproteinases Protein Expressions in Interleukin-1β Stimulated Human Chondrocytes Cells
title_sort effects of payena dasyphylla (miq.) on hyaluronidase enzyme activity and metalloproteinases protein expressions in interleukin-1β stimulated human chondrocytes cells
topic Q Science (General)
url http://umpir.ump.edu.my/id/eprint/6647/
http://umpir.ump.edu.my/id/eprint/6647/
http://umpir.ump.edu.my/id/eprint/6647/
http://umpir.ump.edu.my/id/eprint/6647/3/Effects%20of%20Payena%20dasyphylla%20%28Miq.%29%20on%20Hyaluronidase%20Enzyme%20Activity%20and%20Metalloproteinases%20Protein.pdf