Preliminary Identification of Bioactive Compounds from Commelina nudiflora. L and its Antioxidant, Antibacterial Activities

The methanolic extract of weed plant Commelina nudiflora was evaluated for preliminary phytochemical analysis and its antioxidant, antibacterial activity. The antibacterial activity was determined in the extracts using the agar disc diffusion method. The different concentration (50, 75, 100 μg/ml) o...

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Main Authors: Kuppusamy, Palaniselvam, M. M., Yusoff, Mohammed, Suliman, Gaanty Pragas, Maniam, Natanamurugaraj, Govindan
Format: Conference or Workshop Item
Language:English
Published: 2013
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/5786/
http://umpir.ump.edu.my/id/eprint/5786/1/SCI-015.pdf
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author Kuppusamy, Palaniselvam
M. M., Yusoff
Mohammed, Suliman
Gaanty Pragas, Maniam
Natanamurugaraj, Govindan
author_facet Kuppusamy, Palaniselvam
M. M., Yusoff
Mohammed, Suliman
Gaanty Pragas, Maniam
Natanamurugaraj, Govindan
author_sort Kuppusamy, Palaniselvam
building UMP Institutional Repository
collection Online Access
description The methanolic extract of weed plant Commelina nudiflora was evaluated for preliminary phytochemical analysis and its antioxidant, antibacterial activity. The antibacterial activity was determined in the extracts using the agar disc diffusion method. The different concentration (50, 75, 100 μg/ml) of methanolic extract of Commelina nudiflora was tested against human pathogenic microorganisms. The zone of inhibition of extracts was compared standards as streptomycin for antibacterial activity. The results showed that the significant inhibition of the bacterial growth was shown against E.coli and Salmonella typhi with 11 mm and 9 mm respectively. The phytochemical analyses of the plant extract were carried out by using standard phytochemical methods. Also the free radical scavenging activity of C. nudiflora methanolic extract was subjected into DPPH and ABTS assay. In conclusion the microbial and free radical scavenging activity of the Commelina nudiflora was due to the presence of various secondary metabolites such as saponin, alkaloids, polyphenols and flavonoids. C.nudiflora plant contains a novel bioactive compounds that may serve as control many endemic diseases.
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format Conference or Workshop Item
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institution Universiti Malaysia Pahang
institution_category Local University
language English
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publishDate 2013
recordtype eprints
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spelling ump-57862018-07-27T01:37:45Z http://umpir.ump.edu.my/id/eprint/5786/ Preliminary Identification of Bioactive Compounds from Commelina nudiflora. L and its Antioxidant, Antibacterial Activities Kuppusamy, Palaniselvam M. M., Yusoff Mohammed, Suliman Gaanty Pragas, Maniam Natanamurugaraj, Govindan QK Botany The methanolic extract of weed plant Commelina nudiflora was evaluated for preliminary phytochemical analysis and its antioxidant, antibacterial activity. The antibacterial activity was determined in the extracts using the agar disc diffusion method. The different concentration (50, 75, 100 μg/ml) of methanolic extract of Commelina nudiflora was tested against human pathogenic microorganisms. The zone of inhibition of extracts was compared standards as streptomycin for antibacterial activity. The results showed that the significant inhibition of the bacterial growth was shown against E.coli and Salmonella typhi with 11 mm and 9 mm respectively. The phytochemical analyses of the plant extract were carried out by using standard phytochemical methods. Also the free radical scavenging activity of C. nudiflora methanolic extract was subjected into DPPH and ABTS assay. In conclusion the microbial and free radical scavenging activity of the Commelina nudiflora was due to the presence of various secondary metabolites such as saponin, alkaloids, polyphenols and flavonoids. C.nudiflora plant contains a novel bioactive compounds that may serve as control many endemic diseases. 2013 Conference or Workshop Item PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/5786/1/SCI-015.pdf Kuppusamy, Palaniselvam and M. M., Yusoff and Mohammed, Suliman and Gaanty Pragas, Maniam and Natanamurugaraj, Govindan (2013) Preliminary Identification of Bioactive Compounds from Commelina nudiflora. L and its Antioxidant, Antibacterial Activities. In: Malaysian Technical Universities Conference on Engineering & Technology (MUCET 2013) , 3-4 December 2013 , Kuantan, Pahang. p. 1.. (Published)
spellingShingle QK Botany
Kuppusamy, Palaniselvam
M. M., Yusoff
Mohammed, Suliman
Gaanty Pragas, Maniam
Natanamurugaraj, Govindan
Preliminary Identification of Bioactive Compounds from Commelina nudiflora. L and its Antioxidant, Antibacterial Activities
title Preliminary Identification of Bioactive Compounds from Commelina nudiflora. L and its Antioxidant, Antibacterial Activities
title_full Preliminary Identification of Bioactive Compounds from Commelina nudiflora. L and its Antioxidant, Antibacterial Activities
title_fullStr Preliminary Identification of Bioactive Compounds from Commelina nudiflora. L and its Antioxidant, Antibacterial Activities
title_full_unstemmed Preliminary Identification of Bioactive Compounds from Commelina nudiflora. L and its Antioxidant, Antibacterial Activities
title_short Preliminary Identification of Bioactive Compounds from Commelina nudiflora. L and its Antioxidant, Antibacterial Activities
title_sort preliminary identification of bioactive compounds from commelina nudiflora. l and its antioxidant, antibacterial activities
topic QK Botany
url http://umpir.ump.edu.my/id/eprint/5786/
http://umpir.ump.edu.my/id/eprint/5786/1/SCI-015.pdf