Biosynthesized Gold Nanoparticle Developed as a Tool for Detection of HCG hormone in Pregnant Women Urine Sample
This paper presents a microencapsulation study using whey protein isolate and maltodextrin of polyphenol obtained from Orthosiphon stamineus leaves. Polyphenol content was analysed using ultra-performance liquid chromatography. Higher solid concentration leads to higher solution viscosity, bigger pa...
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| Format: | Article |
| Language: | English |
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Elsevier
2014
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| Online Access: | http://umpir.ump.edu.my/id/eprint/5314/ http://umpir.ump.edu.my/id/eprint/5314/1/fkksa-2014-kuppusamy-art.pdf |
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| author | Kuppusamy, Palaniselvam M. M., Yusoff Gaanty Pragas, Maniam Natanamurugaraj, Govindan |
| author_facet | Kuppusamy, Palaniselvam M. M., Yusoff Gaanty Pragas, Maniam Natanamurugaraj, Govindan |
| author_sort | Kuppusamy, Palaniselvam |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | This paper presents a microencapsulation study using whey protein isolate and maltodextrin of polyphenol obtained from Orthosiphon stamineus leaves. Polyphenol content was analysed using ultra-performance liquid chromatography. Higher solid concentration leads to higher solution viscosity, bigger particle size, lower moisture content and less dented surface, which may improve particle flowability. Microencapsulation using a least amount of protein (0.05wt.%) yielded better retention of romarinic acid (82.08%), sinensetin (79.57%) and eupatorin (81.08%) than those with higher protein concentration. Meanwhile, 5.33 wt.% of maltodextrin provide the highest polyphenol retention of rosmarinic acid (82.67%), sinensetin (82.24%) and eupatorin (80.19%). The results suggest that eupatorin and rosmarinic acid are more susceptible to thermal degradation than sinensetin during spray drying. Formulation using 5.33% maltodextrin provide a better preservation of polyphenols compared to other formulations. |
| first_indexed | 2025-11-15T01:23:57Z |
| format | Article |
| id | ump-5314 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T01:23:57Z |
| publishDate | 2014 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-53142018-07-27T01:35:20Z http://umpir.ump.edu.my/id/eprint/5314/ Biosynthesized Gold Nanoparticle Developed as a Tool for Detection of HCG hormone in Pregnant Women Urine Sample Kuppusamy, Palaniselvam M. M., Yusoff Gaanty Pragas, Maniam Natanamurugaraj, Govindan QR Microbiology This paper presents a microencapsulation study using whey protein isolate and maltodextrin of polyphenol obtained from Orthosiphon stamineus leaves. Polyphenol content was analysed using ultra-performance liquid chromatography. Higher solid concentration leads to higher solution viscosity, bigger particle size, lower moisture content and less dented surface, which may improve particle flowability. Microencapsulation using a least amount of protein (0.05wt.%) yielded better retention of romarinic acid (82.08%), sinensetin (79.57%) and eupatorin (81.08%) than those with higher protein concentration. Meanwhile, 5.33 wt.% of maltodextrin provide the highest polyphenol retention of rosmarinic acid (82.67%), sinensetin (82.24%) and eupatorin (80.19%). The results suggest that eupatorin and rosmarinic acid are more susceptible to thermal degradation than sinensetin during spray drying. Formulation using 5.33% maltodextrin provide a better preservation of polyphenols compared to other formulations. Elsevier 2014 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/5314/1/fkksa-2014-kuppusamy-art.pdf Kuppusamy, Palaniselvam and M. M., Yusoff and Gaanty Pragas, Maniam and Natanamurugaraj, Govindan (2014) Biosynthesized Gold Nanoparticle Developed as a Tool for Detection of HCG hormone in Pregnant Women Urine Sample. Asian Pacific Journal of Tropical Disease, 4 (3). p. 237. ISSN 2222-1808. (Published) http://dx.doi.org/10.1016/S2222-1808(14)60538-7 DOI: 10.1016/S2222-1808(14)60538-7 |
| spellingShingle | QR Microbiology Kuppusamy, Palaniselvam M. M., Yusoff Gaanty Pragas, Maniam Natanamurugaraj, Govindan Biosynthesized Gold Nanoparticle Developed as a Tool for Detection of HCG hormone in Pregnant Women Urine Sample |
| title | Biosynthesized Gold Nanoparticle Developed as a Tool for Detection of HCG hormone in Pregnant Women Urine Sample |
| title_full | Biosynthesized Gold Nanoparticle Developed as a Tool for Detection of HCG hormone in Pregnant Women Urine Sample |
| title_fullStr | Biosynthesized Gold Nanoparticle Developed as a Tool for Detection of HCG hormone in Pregnant Women Urine Sample |
| title_full_unstemmed | Biosynthesized Gold Nanoparticle Developed as a Tool for Detection of HCG hormone in Pregnant Women Urine Sample |
| title_short | Biosynthesized Gold Nanoparticle Developed as a Tool for Detection of HCG hormone in Pregnant Women Urine Sample |
| title_sort | biosynthesized gold nanoparticle developed as a tool for detection of hcg hormone in pregnant women urine sample |
| topic | QR Microbiology |
| url | http://umpir.ump.edu.my/id/eprint/5314/ http://umpir.ump.edu.my/id/eprint/5314/ http://umpir.ump.edu.my/id/eprint/5314/ http://umpir.ump.edu.my/id/eprint/5314/1/fkksa-2014-kuppusamy-art.pdf |