Extraction of glycolic acid from natural sources

Glycolic acid (GA) is a type of alpha hydroxyacetic acid (AHA).It is a small molecule of AHA that is colorless, odorless and hygroscopic. Since GA is capable of penetrate the skin,it is suitable for exfoliate and anti ageing application.It is widely used especially in dermatology, medical and pharma...

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Main Author: Faznurfariza, Firdaus@Nicholas
Format: Undergraduates Project Papers
Language:English
Published: 2012
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/5064/
http://umpir.ump.edu.my/id/eprint/5064/1/Extraction%20of%20glycolic%20acid%20from%20natural%20sources.pdf
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author Faznurfariza, Firdaus@Nicholas
author_facet Faznurfariza, Firdaus@Nicholas
author_sort Faznurfariza, Firdaus@Nicholas
building UMP Institutional Repository
collection Online Access
description Glycolic acid (GA) is a type of alpha hydroxyacetic acid (AHA).It is a small molecule of AHA that is colorless, odorless and hygroscopic. Since GA is capable of penetrate the skin,it is suitable for exfoliate and anti ageing application.It is widely used especially in dermatology, medical and pharmaceutical applications.Since GA is very useful in cosmetic and pharmaceutical field, it yields a high market demand.By using rotten fruits obtained from the market as the sources to produce GA, the waste management in the market could be overcome.Thus,the production cost of GA could be reduced.The purpose of this study is to study the highest production of GA from different type natural sources such as sugarcane juice and banana in term of fresh and rotten state.The study is ought to investigate the effect of concentration of ethylene glycol (0.2 M to 1 M),temperature (40 ⁰C to 80 ⁰C)and time (30 min to 60 min) on extraction of GA compounds from natural sources and to optimize the production of glycolic acid from the sample after screening using response surface methodology (RSM).The ultrasonic homogenizer was used for the extraction of product with different independent variables.HPLC is used to analyze the concentration of GA in the samples.From the present research,fresh banana peels contain the highest GA concentration at 0.914 M.From RSM the most optimum combination variables are temperature at 70 ⁰C,solvent concentration at 1 M and extraction time at 50 min with desirability 1.000.The optimization of GA can be further investigated by using different types of solvent,extraction method and ultrasonic frequency.
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format Undergraduates Project Papers
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institution Universiti Malaysia Pahang
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language English
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publishDate 2012
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spelling ump-50642023-11-16T07:51:06Z http://umpir.ump.edu.my/id/eprint/5064/ Extraction of glycolic acid from natural sources Faznurfariza, Firdaus@Nicholas TP Chemical technology Glycolic acid (GA) is a type of alpha hydroxyacetic acid (AHA).It is a small molecule of AHA that is colorless, odorless and hygroscopic. Since GA is capable of penetrate the skin,it is suitable for exfoliate and anti ageing application.It is widely used especially in dermatology, medical and pharmaceutical applications.Since GA is very useful in cosmetic and pharmaceutical field, it yields a high market demand.By using rotten fruits obtained from the market as the sources to produce GA, the waste management in the market could be overcome.Thus,the production cost of GA could be reduced.The purpose of this study is to study the highest production of GA from different type natural sources such as sugarcane juice and banana in term of fresh and rotten state.The study is ought to investigate the effect of concentration of ethylene glycol (0.2 M to 1 M),temperature (40 ⁰C to 80 ⁰C)and time (30 min to 60 min) on extraction of GA compounds from natural sources and to optimize the production of glycolic acid from the sample after screening using response surface methodology (RSM).The ultrasonic homogenizer was used for the extraction of product with different independent variables.HPLC is used to analyze the concentration of GA in the samples.From the present research,fresh banana peels contain the highest GA concentration at 0.914 M.From RSM the most optimum combination variables are temperature at 70 ⁰C,solvent concentration at 1 M and extraction time at 50 min with desirability 1.000.The optimization of GA can be further investigated by using different types of solvent,extraction method and ultrasonic frequency. 2012-01 Undergraduates Project Papers NonPeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/5064/1/Extraction%20of%20glycolic%20acid%20from%20natural%20sources.pdf Faznurfariza, Firdaus@Nicholas (2012) Extraction of glycolic acid from natural sources. Faculty of Chemical & Natural Resource Engineering, Universiti Malaysia Pahang. http://ecollib.ump.edu.my/20050/
spellingShingle TP Chemical technology
Faznurfariza, Firdaus@Nicholas
Extraction of glycolic acid from natural sources
title Extraction of glycolic acid from natural sources
title_full Extraction of glycolic acid from natural sources
title_fullStr Extraction of glycolic acid from natural sources
title_full_unstemmed Extraction of glycolic acid from natural sources
title_short Extraction of glycolic acid from natural sources
title_sort extraction of glycolic acid from natural sources
topic TP Chemical technology
url http://umpir.ump.edu.my/id/eprint/5064/
http://umpir.ump.edu.my/id/eprint/5064/
http://umpir.ump.edu.my/id/eprint/5064/1/Extraction%20of%20glycolic%20acid%20from%20natural%20sources.pdf