Chemical And Biological Studies Of Zingiber Phillipseae Rhizomes Extract

A novel flavonoidic compound, 3,5-dihydroxy-4’,7-dimethoxyflavone, has been isolated from the rhizomes of Zingiber phillipseae. The dichloromethane extract of this species was shown to be non-toxic with LC50 for acute and toxic levels at 9,732 ppm and 562ppm, respectively. The extract showed higher...

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Main Authors: M. M., Yusoff, Tan, Wei Hsiang
Format: Article
Language:English
Published: IJPBS, India 2012
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/4732/
http://umpir.ump.edu.my/id/eprint/4732/1/fist-2012-mashitah-ChemicalAndBiological.pdf
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author M. M., Yusoff
Tan, Wei Hsiang
author_facet M. M., Yusoff
Tan, Wei Hsiang
author_sort M. M., Yusoff
building UMP Institutional Repository
collection Online Access
description A novel flavonoidic compound, 3,5-dihydroxy-4’,7-dimethoxyflavone, has been isolated from the rhizomes of Zingiber phillipseae. The dichloromethane extract of this species was shown to be non-toxic with LC50 for acute and toxic levels at 9,732 ppm and 562ppm, respectively. The extract showed higher antioxidant activity than the standard (butylated hydroxytoluene, BHT) but lower than dichloromethane extract of Zingiber officinale. It showed significant activity against Staphylococcus aureus and Escherichia coli with minimum inhibitory concentration (MIC) at 200µg/ml and 225 µg/ml respectively. Both extracts were found negative toward Candida albicans.
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spelling ump-47322018-07-27T03:26:02Z http://umpir.ump.edu.my/id/eprint/4732/ Chemical And Biological Studies Of Zingiber Phillipseae Rhizomes Extract M. M., Yusoff Tan, Wei Hsiang Q Science (General) QD Chemistry A novel flavonoidic compound, 3,5-dihydroxy-4’,7-dimethoxyflavone, has been isolated from the rhizomes of Zingiber phillipseae. The dichloromethane extract of this species was shown to be non-toxic with LC50 for acute and toxic levels at 9,732 ppm and 562ppm, respectively. The extract showed higher antioxidant activity than the standard (butylated hydroxytoluene, BHT) but lower than dichloromethane extract of Zingiber officinale. It showed significant activity against Staphylococcus aureus and Escherichia coli with minimum inhibitory concentration (MIC) at 200µg/ml and 225 µg/ml respectively. Both extracts were found negative toward Candida albicans. IJPBS, India 2012-10-03 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/4732/1/fist-2012-mashitah-ChemicalAndBiological.pdf M. M., Yusoff and Tan, Wei Hsiang (2012) Chemical And Biological Studies Of Zingiber Phillipseae Rhizomes Extract. International Journal of Pharma & Bio Sciences, 3 (4). pp. 629-637. ISSN 0975-6299. (Published) http://www.ijpbs.net/download.php?download_file=vol-3/issue-4/Pharma/66.pdf&did=1824
spellingShingle Q Science (General)
QD Chemistry
M. M., Yusoff
Tan, Wei Hsiang
Chemical And Biological Studies Of Zingiber Phillipseae Rhizomes Extract
title Chemical And Biological Studies Of Zingiber Phillipseae Rhizomes Extract
title_full Chemical And Biological Studies Of Zingiber Phillipseae Rhizomes Extract
title_fullStr Chemical And Biological Studies Of Zingiber Phillipseae Rhizomes Extract
title_full_unstemmed Chemical And Biological Studies Of Zingiber Phillipseae Rhizomes Extract
title_short Chemical And Biological Studies Of Zingiber Phillipseae Rhizomes Extract
title_sort chemical and biological studies of zingiber phillipseae rhizomes extract
topic Q Science (General)
QD Chemistry
url http://umpir.ump.edu.my/id/eprint/4732/
http://umpir.ump.edu.my/id/eprint/4732/
http://umpir.ump.edu.my/id/eprint/4732/1/fist-2012-mashitah-ChemicalAndBiological.pdf