Fungal biofactories for the formulation of nanocomposites for therapeutic applications
Fungal biofactories offer an innovative, eco-friendly platform for producing nanocomposites with therapeutic applications. Fungi possess remarkable metabolic capabilities, enabling them to synthesize a wide range of bioactive compounds, including enzymes, secondary metabolites, and biopolymers. Thes...
| Main Authors: | , , , , , , |
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| Format: | Book Chapter |
| Language: | English English |
| Published: |
Springer Nature
2025
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| Online Access: | https://umpir.ump.edu.my/id/eprint/45929/ |
| _version_ | 1848827528589869056 |
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| author | Gobi, Krishantinee Norliana, Munir Shoriya Aruni, Abdul Manaf Aizi Nor Mazila, Ramli Dailin, Daniel Joe Nur Farzana, Ahmad Sanadi Nor Hasmaliana, Abdul Manas |
| author_facet | Gobi, Krishantinee Norliana, Munir Shoriya Aruni, Abdul Manaf Aizi Nor Mazila, Ramli Dailin, Daniel Joe Nur Farzana, Ahmad Sanadi Nor Hasmaliana, Abdul Manas |
| author_sort | Gobi, Krishantinee |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Fungal biofactories offer an innovative, eco-friendly platform for producing nanocomposites with therapeutic applications. Fungi possess remarkable metabolic capabilities, enabling them to synthesize a wide range of bioactive compounds, including enzymes, secondary metabolites, and biopolymers. These natural resources can be harnessed in the formulation of nanocomposites, which are nanoscale materials made from multiple components, typically offering enhanced properties like improved drug delivery, biocompatibility, and antimicrobial activity. This chapter introduces fungi as biofactories, structure and types of nanocomposites, mechanism of fungal nanoparticle formation, and therapeutic applications of fungal nanocomposites. The use of fungi in nanocomposite synthesis is particularly attractive due to their ability to reduce metal ions, stabilize nanoparticles, and produce biopolymers like chitosan and polysaccharides, which can act as natural matrices or coatings for nanomaterials. These fungal-derived nanocomposites can be designed to encapsulate therapeutic agents, including drugs, peptides, or biomolecules, allowing for controlled and targeted delivery in medical applications. Advantages, challenges, and future perspectives of fungal biofactories are also discussed. Fungal biofactories provide a sustainable approach, minimizing toxic chemicals commonly used in conventional nanomaterial synthesis and reducing environmental impact. Their versatility in producing various functional materials opens the door to developing advanced therapies, such as antimicrobial treatments, cancer therapies, and regenerative medicine. Overall, fungi represent a promising avenue for advancing nanotechnology in healthcare. |
| first_indexed | 2025-11-15T04:02:09Z |
| format | Book Chapter |
| id | ump-45929 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T04:02:09Z |
| publishDate | 2025 |
| publisher | Springer Nature |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-459292025-10-15T06:21:11Z https://umpir.ump.edu.my/id/eprint/45929/ Fungal biofactories for the formulation of nanocomposites for therapeutic applications Gobi, Krishantinee Norliana, Munir Shoriya Aruni, Abdul Manaf Aizi Nor Mazila, Ramli Dailin, Daniel Joe Nur Farzana, Ahmad Sanadi Nor Hasmaliana, Abdul Manas HD Industries. Land use. Labor TP Chemical technology Fungal biofactories offer an innovative, eco-friendly platform for producing nanocomposites with therapeutic applications. Fungi possess remarkable metabolic capabilities, enabling them to synthesize a wide range of bioactive compounds, including enzymes, secondary metabolites, and biopolymers. These natural resources can be harnessed in the formulation of nanocomposites, which are nanoscale materials made from multiple components, typically offering enhanced properties like improved drug delivery, biocompatibility, and antimicrobial activity. This chapter introduces fungi as biofactories, structure and types of nanocomposites, mechanism of fungal nanoparticle formation, and therapeutic applications of fungal nanocomposites. The use of fungi in nanocomposite synthesis is particularly attractive due to their ability to reduce metal ions, stabilize nanoparticles, and produce biopolymers like chitosan and polysaccharides, which can act as natural matrices or coatings for nanomaterials. These fungal-derived nanocomposites can be designed to encapsulate therapeutic agents, including drugs, peptides, or biomolecules, allowing for controlled and targeted delivery in medical applications. Advantages, challenges, and future perspectives of fungal biofactories are also discussed. Fungal biofactories provide a sustainable approach, minimizing toxic chemicals commonly used in conventional nanomaterial synthesis and reducing environmental impact. Their versatility in producing various functional materials opens the door to developing advanced therapies, such as antimicrobial treatments, cancer therapies, and regenerative medicine. Overall, fungi represent a promising avenue for advancing nanotechnology in healthcare. Springer Nature 2025 Book Chapter PeerReviewed pdf en https://umpir.ump.edu.my/id/eprint/45929/1/Book%20cover%20n%20Intro%20Chapter%20Fungal%20Biofactories%20for%20the%20Formulation.pdf pdf en https://umpir.ump.edu.my/id/eprint/45929/2/Fungal%20Biofactories%20for%20the%20Formulation%20of%20Nanocomposites%20for%20Therapeutic%20Applications.pdf Gobi, Krishantinee and Norliana, Munir and Shoriya Aruni, Abdul Manaf and Aizi Nor Mazila, Ramli and Dailin, Daniel Joe and Nur Farzana, Ahmad Sanadi and Nor Hasmaliana, Abdul Manas (2025) Fungal biofactories for the formulation of nanocomposites for therapeutic applications. In: Bioprospecting of Multi-tasking Fungi for Therapeutic Applications: Volume II. Volume II, II . Springer Nature, pp. 181-202. ISBN 978-981962975-6, 978-981962974-9 https://doi.org/10.1007/978-981-96-2975-6_8 |
| spellingShingle | HD Industries. Land use. Labor TP Chemical technology Gobi, Krishantinee Norliana, Munir Shoriya Aruni, Abdul Manaf Aizi Nor Mazila, Ramli Dailin, Daniel Joe Nur Farzana, Ahmad Sanadi Nor Hasmaliana, Abdul Manas Fungal biofactories for the formulation of nanocomposites for therapeutic applications |
| title | Fungal biofactories for the formulation of nanocomposites for therapeutic applications |
| title_full | Fungal biofactories for the formulation of nanocomposites for therapeutic applications |
| title_fullStr | Fungal biofactories for the formulation of nanocomposites for therapeutic applications |
| title_full_unstemmed | Fungal biofactories for the formulation of nanocomposites for therapeutic applications |
| title_short | Fungal biofactories for the formulation of nanocomposites for therapeutic applications |
| title_sort | fungal biofactories for the formulation of nanocomposites for therapeutic applications |
| topic | HD Industries. Land use. Labor TP Chemical technology |
| url | https://umpir.ump.edu.my/id/eprint/45929/ https://umpir.ump.edu.my/id/eprint/45929/ |