Multiphysics Simulation of Blood Flow in Heart with Ventricular Septal Defect
Ventricular septal defect (VSD) is the presence of a hole in the septum connecting both left and right ventricles of the heart, which allows the blood to flow in between them. VSD usually occurs in infants, and many will spontaneously close as they age. Therefore, the purpose of this study is to inv...
| Main Authors: | , , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
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Springer
2024
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| Online Access: | https://umpir.ump.edu.my/id/eprint/45335/ |
| _version_ | 1848827387407499264 |
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| author | Ahmad Fikri Azfar, Ahmad Azaharia Mohd Akramin, Mohd Romlay Mohd Jamil, Mohamed Mokhtarudin Azam, Ahmad Bakir |
| author_facet | Ahmad Fikri Azfar, Ahmad Azaharia Mohd Akramin, Mohd Romlay Mohd Jamil, Mohamed Mokhtarudin Azam, Ahmad Bakir |
| author_sort | Ahmad Fikri Azfar, Ahmad Azaharia |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Ventricular septal defect (VSD) is the presence of a hole in the septum connecting both left and right ventricles of the heart, which allows the blood to flow in between them. VSD usually occurs in infants, and many will spontaneously close as they age. Therefore, the purpose of this study is to investigate the effect of VSD presence in a biventricular model using Multiphysics simulation involving myocardium mechanics, blood flow, and electrophysiology. Idealized biventricular geometry is used and a VSD of 6 mm diameter is introduced in the septum. In this study, the Multiphysics simulations of a normal heart and a VSD heart have been performed, involving the ventricular wall mechanics, blood flow, and electrophysiology. It is found that for the normal heart, the left ventricular pressure and volume are slightly higher, while the right ventricular pressure and volume are slightly lower than the VSD heart. This is due to the increased amount of blood flowing into the right ventricle chamber in VSD heart from the left ventricle. Further investigation using bigger diameter and location of VSD could uncover more understanding on the differences. |
| first_indexed | 2025-11-15T03:59:54Z |
| format | Conference or Workshop Item |
| id | ump-45335 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T03:59:54Z |
| publishDate | 2024 |
| publisher | Springer |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-453352025-08-11T03:23:57Z https://umpir.ump.edu.my/id/eprint/45335/ Multiphysics Simulation of Blood Flow in Heart with Ventricular Septal Defect Ahmad Fikri Azfar, Ahmad Azaharia Mohd Akramin, Mohd Romlay Mohd Jamil, Mohamed Mokhtarudin Azam, Ahmad Bakir RS Pharmacy and materia medica TJ Mechanical engineering and machinery Ventricular septal defect (VSD) is the presence of a hole in the septum connecting both left and right ventricles of the heart, which allows the blood to flow in between them. VSD usually occurs in infants, and many will spontaneously close as they age. Therefore, the purpose of this study is to investigate the effect of VSD presence in a biventricular model using Multiphysics simulation involving myocardium mechanics, blood flow, and electrophysiology. Idealized biventricular geometry is used and a VSD of 6 mm diameter is introduced in the septum. In this study, the Multiphysics simulations of a normal heart and a VSD heart have been performed, involving the ventricular wall mechanics, blood flow, and electrophysiology. It is found that for the normal heart, the left ventricular pressure and volume are slightly higher, while the right ventricular pressure and volume are slightly lower than the VSD heart. This is due to the increased amount of blood flowing into the right ventricle chamber in VSD heart from the left ventricle. Further investigation using bigger diameter and location of VSD could uncover more understanding on the differences. Springer 2024-10-12 Conference or Workshop Item PeerReviewed pdf en https://umpir.ump.edu.my/id/eprint/45335/1/artikel1.pdf Ahmad Fikri Azfar, Ahmad Azaharia and Mohd Akramin, Mohd Romlay and Mohd Jamil, Mohamed Mokhtarudin and Azam, Ahmad Bakir (2024) Multiphysics Simulation of Blood Flow in Heart with Ventricular Septal Defect. In: Proceedings of the Annual Congress of the Asia-Pacific Society for Artificial Organs. APSAO 2023. Lecture Notes in Bioengineering; Annual Congress of the Asia-Pacific Society for Artificial Organs, APSAO 2023 , 25 - 26 September 2023 , Kuala Lumpur. pp. 173-182.. ISSN 2195-271X ISBN 978-981972110-8 (Published) https://doi.org/10.1007/978-981-97-1920-4_17 |
| spellingShingle | RS Pharmacy and materia medica TJ Mechanical engineering and machinery Ahmad Fikri Azfar, Ahmad Azaharia Mohd Akramin, Mohd Romlay Mohd Jamil, Mohamed Mokhtarudin Azam, Ahmad Bakir Multiphysics Simulation of Blood Flow in Heart with Ventricular Septal Defect |
| title | Multiphysics Simulation of Blood Flow in Heart with Ventricular Septal Defect |
| title_full | Multiphysics Simulation of Blood Flow in Heart with Ventricular Septal Defect |
| title_fullStr | Multiphysics Simulation of Blood Flow in Heart with Ventricular Septal Defect |
| title_full_unstemmed | Multiphysics Simulation of Blood Flow in Heart with Ventricular Septal Defect |
| title_short | Multiphysics Simulation of Blood Flow in Heart with Ventricular Septal Defect |
| title_sort | multiphysics simulation of blood flow in heart with ventricular septal defect |
| topic | RS Pharmacy and materia medica TJ Mechanical engineering and machinery |
| url | https://umpir.ump.edu.my/id/eprint/45335/ https://umpir.ump.edu.my/id/eprint/45335/ |