Surface composition, adhesion strength and biocompatibility activity of CoCrMo-Hydroxyapatite composite
Hydroxyapatite (HA) has been considered one of the most efficient surface modification implant components for enhancing osteointegration. However, post-traumatic inflammation or swelling stands out as one of the substantial obstacles in reconstructive surgery involving Cobalt-Chrome-Molybdenum (CoCr...
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| Format: | Article |
| Language: | English |
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Elsevier Ltd
2025
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| Online Access: | http://umpir.ump.edu.my/id/eprint/45052/ http://umpir.ump.edu.my/id/eprint/45052/1/Surface%20composition%2C%20adhesion%20strength%20and%20biocompatibility%20activity.pdf |
| _version_ | 1848827244357615616 |
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| author | Nurul Akmal, Che Lah Mas Ayu, Hassan Rosdi, Daud |
| author_facet | Nurul Akmal, Che Lah Mas Ayu, Hassan Rosdi, Daud |
| author_sort | Nurul Akmal, Che Lah |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Hydroxyapatite (HA) has been considered one of the most efficient surface modification implant components for enhancing osteointegration. However, post-traumatic inflammation or swelling stands out as one of the substantial obstacles in reconstructive surgery involving Cobalt-Chrome-Molybdenum (CoCrMo) orthopaedic implants. Continuous efforts have been made to increase the success towards improving the surface-modified CoCrMo-HA interface and its impact on ion release, the primary mechanisms of degradation. Herein, the present study endeavours to report a detailed surface composition analysis of fabricated CoCrMo-HA alloys, highlighting the changes in surface bioactivity and metal ion release, as influenced by the sintering temperatures. Notably, CoCrMo-HA850 alloy sintered at 750 °C disclosed the most compromised system for better surface modification, improved biocompatibility and metal ion release activity properties. Parallelly, a comparative analysis of scaffolds composed of the scaffold poly lactic acid (PLA) reinforced with HA, forming CoCrMo-PLA/HA composites and another sample incorporating foreign ion magnesium, Mg with HA forming CoCrMo-Mg/HA composite. The incorporation of PLA and Mg into CoCrMo-HA structures yields distinct nucleation, cracking and propagation features due to varying system stabilities. The discoveries reported in this work are crucial for advancing understanding and to re-think improved CoCrMo-HA systems for future applications in bone regeneration implants and scaffolds. |
| first_indexed | 2025-11-15T03:57:38Z |
| format | Article |
| id | ump-45052 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T03:57:38Z |
| publishDate | 2025 |
| publisher | Elsevier Ltd |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-450522025-07-10T03:33:49Z http://umpir.ump.edu.my/id/eprint/45052/ Surface composition, adhesion strength and biocompatibility activity of CoCrMo-Hydroxyapatite composite Nurul Akmal, Che Lah Mas Ayu, Hassan Rosdi, Daud QD Chemistry TA Engineering (General). Civil engineering (General) TJ Mechanical engineering and machinery Hydroxyapatite (HA) has been considered one of the most efficient surface modification implant components for enhancing osteointegration. However, post-traumatic inflammation or swelling stands out as one of the substantial obstacles in reconstructive surgery involving Cobalt-Chrome-Molybdenum (CoCrMo) orthopaedic implants. Continuous efforts have been made to increase the success towards improving the surface-modified CoCrMo-HA interface and its impact on ion release, the primary mechanisms of degradation. Herein, the present study endeavours to report a detailed surface composition analysis of fabricated CoCrMo-HA alloys, highlighting the changes in surface bioactivity and metal ion release, as influenced by the sintering temperatures. Notably, CoCrMo-HA850 alloy sintered at 750 °C disclosed the most compromised system for better surface modification, improved biocompatibility and metal ion release activity properties. Parallelly, a comparative analysis of scaffolds composed of the scaffold poly lactic acid (PLA) reinforced with HA, forming CoCrMo-PLA/HA composites and another sample incorporating foreign ion magnesium, Mg with HA forming CoCrMo-Mg/HA composite. The incorporation of PLA and Mg into CoCrMo-HA structures yields distinct nucleation, cracking and propagation features due to varying system stabilities. The discoveries reported in this work are crucial for advancing understanding and to re-think improved CoCrMo-HA systems for future applications in bone regeneration implants and scaffolds. Elsevier Ltd 2025 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/45052/1/Surface%20composition%2C%20adhesion%20strength%20and%20biocompatibility%20activity.pdf Nurul Akmal, Che Lah and Mas Ayu, Hassan and Rosdi, Daud (2025) Surface composition, adhesion strength and biocompatibility activity of CoCrMo-Hydroxyapatite composite. Composite Structures, 370 (119391). pp. 1-19. ISSN 0263-8223. (Published) https://doi.org/10.1016/j.compstruct.2025.119391 https://doi.org/10.1016/j.compstruct.2025.119391 |
| spellingShingle | QD Chemistry TA Engineering (General). Civil engineering (General) TJ Mechanical engineering and machinery Nurul Akmal, Che Lah Mas Ayu, Hassan Rosdi, Daud Surface composition, adhesion strength and biocompatibility activity of CoCrMo-Hydroxyapatite composite |
| title | Surface composition, adhesion strength and biocompatibility activity of CoCrMo-Hydroxyapatite composite |
| title_full | Surface composition, adhesion strength and biocompatibility activity of CoCrMo-Hydroxyapatite composite |
| title_fullStr | Surface composition, adhesion strength and biocompatibility activity of CoCrMo-Hydroxyapatite composite |
| title_full_unstemmed | Surface composition, adhesion strength and biocompatibility activity of CoCrMo-Hydroxyapatite composite |
| title_short | Surface composition, adhesion strength and biocompatibility activity of CoCrMo-Hydroxyapatite composite |
| title_sort | surface composition, adhesion strength and biocompatibility activity of cocrmo-hydroxyapatite composite |
| topic | QD Chemistry TA Engineering (General). Civil engineering (General) TJ Mechanical engineering and machinery |
| url | http://umpir.ump.edu.my/id/eprint/45052/ http://umpir.ump.edu.my/id/eprint/45052/ http://umpir.ump.edu.my/id/eprint/45052/ http://umpir.ump.edu.my/id/eprint/45052/1/Surface%20composition%2C%20adhesion%20strength%20and%20biocompatibility%20activity.pdf |