Machine learning classifications of multiple organ failures in a malaysian intensive care unit

Multiple organ failures are the main cause of mortality and morbidity in the intensive care unit (ICU). The progression of organ failures in the ICU is usually monitored using the Sequential Organ Failure Assessment (SOFA) score. This study aims to perform the classification of multiple organ failur...

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Main Authors: Norliyana, Nor Hisham Shah, Normy Norfiza, Abdul Razak, Athirah, Abdul Razak, Asma’, Abu-Samah, Fatanah, M. Suhaimi, Ummu Kulthum, Jamaludin
Format: Article
Language:English
Published: Penerbit UTHM 2024
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/44737/
http://umpir.ump.edu.my/id/eprint/44737/1/Machine%20learning%20classifications%20of%20multiple%20organ%20failures%20in%20a%20malaysian.pdf
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author Norliyana, Nor Hisham Shah
Normy Norfiza, Abdul Razak
Athirah, Abdul Razak
Asma’, Abu-Samah
Fatanah, M. Suhaimi
Ummu Kulthum, Jamaludin
author_facet Norliyana, Nor Hisham Shah
Normy Norfiza, Abdul Razak
Athirah, Abdul Razak
Asma’, Abu-Samah
Fatanah, M. Suhaimi
Ummu Kulthum, Jamaludin
author_sort Norliyana, Nor Hisham Shah
building UMP Institutional Repository
collection Online Access
description Multiple organ failures are the main cause of mortality and morbidity in the intensive care unit (ICU). The progression of organ failures in the ICU is usually monitored using the Sequential Organ Failure Assessment (SOFA) score. This study aims to perform the classification of multiple organ failures using machine learning algorithms based on SOFA score. Ninety-eight ICU patients’ data were obtained retrospectively from Universiti Malaya Medical Centre for analysis. Several machine learning algorithms which are decision tree, linear discriminant, naïve Bayes, support vector machines, k-nearest neighbor, AdaBoost, and random forest were used for the classification. The classifiers were trained on 80% of the patients with 10-fold cross-validations and assessed on 20% of patients using 34 variables in the ICU. The random forest algorithm was able to achieve 99.8% accuracy and 99.9% sensitivity in the training dataset. Meanwhile, the AdaBoost algorithm achieved 99.1% sensitivity in the testing dataset. This study demonstrates the performances of different machine learning algorithms in the classification of multiple organ failures. The feature selection shows respiratory rate and mean arterial pressure (MAP) as the most important variables using chi-square test while insulin and fraction of oxygenated hemoglobin are the most important predictors by the mutual information test.
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spelling ump-447372025-06-06T03:32:37Z http://umpir.ump.edu.my/id/eprint/44737/ Machine learning classifications of multiple organ failures in a malaysian intensive care unit Norliyana, Nor Hisham Shah Normy Norfiza, Abdul Razak Athirah, Abdul Razak Asma’, Abu-Samah Fatanah, M. Suhaimi Ummu Kulthum, Jamaludin QA75 Electronic computers. Computer science TJ Mechanical engineering and machinery Multiple organ failures are the main cause of mortality and morbidity in the intensive care unit (ICU). The progression of organ failures in the ICU is usually monitored using the Sequential Organ Failure Assessment (SOFA) score. This study aims to perform the classification of multiple organ failures using machine learning algorithms based on SOFA score. Ninety-eight ICU patients’ data were obtained retrospectively from Universiti Malaya Medical Centre for analysis. Several machine learning algorithms which are decision tree, linear discriminant, naïve Bayes, support vector machines, k-nearest neighbor, AdaBoost, and random forest were used for the classification. The classifiers were trained on 80% of the patients with 10-fold cross-validations and assessed on 20% of patients using 34 variables in the ICU. The random forest algorithm was able to achieve 99.8% accuracy and 99.9% sensitivity in the training dataset. Meanwhile, the AdaBoost algorithm achieved 99.1% sensitivity in the testing dataset. This study demonstrates the performances of different machine learning algorithms in the classification of multiple organ failures. The feature selection shows respiratory rate and mean arterial pressure (MAP) as the most important variables using chi-square test while insulin and fraction of oxygenated hemoglobin are the most important predictors by the mutual information test. Penerbit UTHM 2024 Article PeerReviewed pdf en cc_by_nc_sa_4 http://umpir.ump.edu.my/id/eprint/44737/1/Machine%20learning%20classifications%20of%20multiple%20organ%20failures%20in%20a%20malaysian.pdf Norliyana, Nor Hisham Shah and Normy Norfiza, Abdul Razak and Athirah, Abdul Razak and Asma’, Abu-Samah and Fatanah, M. Suhaimi and Ummu Kulthum, Jamaludin (2024) Machine learning classifications of multiple organ failures in a malaysian intensive care unit. International Journal of Integrated Engineering, 16 (2). pp. 114-122. ISSN 2229-838X. (Published) https://doi.org/10.30880/ijie.2024.16.02.012 https://doi.org/10.30880/ijie.2024.16.02.012
spellingShingle QA75 Electronic computers. Computer science
TJ Mechanical engineering and machinery
Norliyana, Nor Hisham Shah
Normy Norfiza, Abdul Razak
Athirah, Abdul Razak
Asma’, Abu-Samah
Fatanah, M. Suhaimi
Ummu Kulthum, Jamaludin
Machine learning classifications of multiple organ failures in a malaysian intensive care unit
title Machine learning classifications of multiple organ failures in a malaysian intensive care unit
title_full Machine learning classifications of multiple organ failures in a malaysian intensive care unit
title_fullStr Machine learning classifications of multiple organ failures in a malaysian intensive care unit
title_full_unstemmed Machine learning classifications of multiple organ failures in a malaysian intensive care unit
title_short Machine learning classifications of multiple organ failures in a malaysian intensive care unit
title_sort machine learning classifications of multiple organ failures in a malaysian intensive care unit
topic QA75 Electronic computers. Computer science
TJ Mechanical engineering and machinery
url http://umpir.ump.edu.my/id/eprint/44737/
http://umpir.ump.edu.my/id/eprint/44737/
http://umpir.ump.edu.my/id/eprint/44737/
http://umpir.ump.edu.my/id/eprint/44737/1/Machine%20learning%20classifications%20of%20multiple%20organ%20failures%20in%20a%20malaysian.pdf