Inhibitory effect of (2S)-pinocembrin from goniothalamus macrophyllus on the prostaglandin E2 production in macrophage cell lines

QR Code

Inhibitory effect of (2S)-pinocembrin from goniothalamus macrophyllus on the prostaglandin E2 production in macrophage cell lines

Pinocembrin (PCB), a flavonoid known for its anti-inflammatory properties, has been approved for various clinical trial applications. To evaluate deeper into the anti-inflammatory potential of the specific enantiomer of natural PCB, we conducted the first investigation into the efficacy of the pure...

Full description

Bibliographic Details
Main Authors:	Hilwan Yuda, Teruna, Kamal, Rullah, Hendra, Rudi, Utami, Rahayu, Islami, Deri, Siti Munirah, Mohd Faudzi, Mohd Fadhlizil Fasihi, Mohd Aluwi, Lam, Kok Wai
Format:	Article
Language:	English
Published:	John Wiley & Sons Ltd 2024
Subjects:	Q Science (General) QP Physiology
Online Access:	https://umpir.ump.edu.my/id/eprint/44196/

Similar Items

Inhibitory effect of (2s)-Pinocembrin from Goniothalamus macrophyllus on the Prostaglandin E2 production in macrophage cell lines
by: Teruna, Hilwan Yuda, et al.
Published: (2024)

Phytochemical studies and biological activity of goniothalamus macrophyllus
by: Nurfarahen, Binti Jamil
Published: (2012)

Penilaian Kandungan Goniothalamin Dalam Goniothalamus Macrophyllus Dari Pulau Langkawi.
by: Chew, Giok Mian
Published: (1992)

Chemical constituents from the hexane fraction of Goniothalamus Macrophyllus roots / Norkamilah Mohammed @ Abdullah
by: Mohammed @ Abdullah, Norkamilah
Published: (2013)

Synthesis of unsymmetrical monocarbonyl curcumin analogues with potent inhibition on prostaglandin E2 production in LPS-induced murine and human macrophages cell lines
by: Mohd Aluwi, Mohd Fadhlizil Fasihi, et al.
Published: (2016)

Synthesis of unsymmetrical monocarbonyl curcumin analogues with potent inhibition on prostaglandin E2 production in LPS-induced murine and human macrophages cell lines
by: Mohd Aluwi, Mohd Fadhlizil Fasihi, et al.
Published: (2016)

Chemical constituents and antimicrobial activity of Goniothalamus macrophyllus (Annonaceae) from Pasoh Forest Reserve, Malaysia
by: Ab Ghani, Siti Humeirah, et al.
Published: (2010)

Synthesis, In silico molecular docking modeling and pharmacophore mapping of (E)-3-(4-hydroxy-2,6-dimethoxyphenyl)-1-phenylprop-2-en-1- one as potential new inhibitor of microsomal prostaglandin E synthase-1
by: Sanphetchaloemchok, Pitipat, et al.
Published: (2020)

Inhibition of prostaglandin E-2 production by synthetic minor prenylated chalcones and flavonoids: Synthesis, biological activity, crystal structure, and in silico evaluation
by: Kamal, Rullah, et al.
Published: (2014)

Inhibition of prostaglandin E2 production by synthetic minor prenylated chalcones and flavonoids: synthesis, biological activity, crystal structure, and in silico evaluation
by: Rullah, Kamal, et al.
Published: (2014)

Inhibition of nitric oxide and prostaglandin E2 production by pyrrolylated-chalcones: synthesis, biological activity, crystal structure analysis, and molecular docking studies
by: Mohd Faudzi, Siti Munirah, et al.
Published: (2020)

Inhibition of nitric oxide and prostaglandin E2 production by pyrrolylated-chalcones: synthesis, biological activity, crystal structure analysis, and molecular docking studies
by: Mohd Faudzi, Siti Munirah, et al.
Published: (2020)

Molecular characterization, biological activity, and in silico study of 2-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-6-methoxy-4H-chromen-4-one as a novel selective COX-2 inhibitor
by: Rullah, Kamal, et al.
Published: (2015)

Synthesis and SAR studies of new chromone derivatives as Inhibitors of PGE2 production
by: Rullah, Kamal, et al.
Published: (2019)

Isolation and synthesis of pinocembrin and pinostrobin from Artocarpus odoratissimus [Pemencilan dan sintesis pinocembrin dan pinostrobin dari Artocarpus odoratissimus]
by: Nyokat, Nyotia, et al.
Published: (2017)

Evolution of SARS-CoV-2 from BA.2.86 to JN.1 variations and detection in Bangladesh
by: Roney, Miah, et al.
Published: (2024)

Design and in-silico studies of abacavir analogues as Anti-DENV-2 NS5 methyltransferase
by: Roney, Miah, et al.
Published: (2025)

Identification of novel 5-lipoxygenase-activating protein (FLAP) inhibitors by an integrated method of pharmacophore virtual screening, docking, QSAR and ADMET analyses
by: Rullah, Kamal, et al.
Published: (2023)

A curcumin derivative, 2,6-bis(2,5-dimethoxybenzylidene)-cyclohexanone (BDMC33) attenuates prostaglandin E2 synthesis via selective suppression of cyclooxygenase-2 in IFN-γ/LPS-stimulated macrophages..
by: Lee, Ka Heng, et al.
Published: (2011)

Deciphering the mechanism of usnic acid in type 2 diabetes treatment: A network pharmacology and molecular docking approach
by: Roney, Miah, et al.
Published: (2025)

Inhibition of nitric oxide and prostaglandin E2 production by pyrrolylated-chalcones : synthesis, biological activity, crystal structure analysis, and molecular docking studies
by: Siti Munirah, Mohd Faudzi, et al.
Published: (2020)

Chemical constituents and cytotoxic properties of Goniothelamus Macrophyllus / Hamidah Sahibul Anwar
by: Sahibul Anwar, Hamidah
Published: (2008)

Induction of parturition in crossbred sows with cloprostenol, an analogue of prostaglandin F2α
by: Jainudeen, M.R., et al.
Published: (1980)

Induction of labour with Prostaglandin in previous scar
by: Ismail, Norhashimah, et al.
Published: (2017)

Chemical studies and biological activities of Goniothalamus Tapis Miq and Goniothalamus Velutinus Airy Shaw
by: Nabihah, Hamdan
Published: (2014)

Phytochemical studies on goniothalamus woodii
by: Fasihuddin , B. A., et al.
Published: (1996)

A synthetic hydroxypropenone inhibits nitric oxide, prostaglandin E2, and proinflammatory cytokine synthesis
by: Liew, Choi Yi, et al.
Published: (2010)

Kajian fitokimia dan penyaringan biologi ke atas goniothalamus velutinus dan goniothalamus uvarioides
by: Wong, Mui Hung
Published: (2007)

Chemical studies and biological activities of goniothalamus tapisoides
by: Mohd Alhafiizh, Zailani
Published: (2008)

Concerns regarding SARS-CoV-2 JN.1 mutations should be raised
by: Roney, Miah, et al.
Published: (2024)

Effects of resynchronization with progesterone and prostaglandin F2• on estrus response and pregnancy rate in beef cattle
by: A. Malik,, et al.
Published: (2011)

The effects of Prostaglandin J2 metabolite on selected apoptotic signaling molecules in UeLa cells
by: Rabail, Nasir Aziz
Published: (2006)

Inhibitory effect of Sinapic acid derivatives targeting structural and non-structural proteins of dengue virus serotype 2 An in-silico assessment
by: Roney, Miah, et al.
Published: (2023)

Chemical constituents and antiviral study of Goniothalamus velutinus
by: Fasihuddin Badruddin,, Ahmad, et al.
Published: (2014)

Isolation and characterization of styryllactone of Goniothalamus ridleyi
by: Samsiah Jusoh,, et al.
Published: (2015)

Phythochemical and biological studies on goniothalamus malayanus
by: Hamdan, Asfiar
Published: (2005)

Isolation and Characterization of Styryllactone of Goniothalamus ridleyi
by: Fasihuddin b., Ahmad, et al.
Published: (2015)

Regulation Of Macrophage Cellular Response By Clinacanthus Nutans Extracts In J774.2 Macrophage Cell Line
by: Mohamed, Nur Mazidah Haji Noor
Published: (2019)

Insights on the synthesis of asymmetric curcumin derivatives and their biological activities
by: Rullah, Malaysia, et al.
Published: (2019)

Anti-diabetic activity of phloretin against maltase-glucoamylase using docking, pharmacokinetics and pharmacophore studies
by: Roney, Miah, et al.
Published: (2023)