Development of bioactive patches from aloe vera and Nata De Coco for wound dressing applications
This study focuses on the development and characterization of bioactive patches derived from Aloe Vera (AV) and Nata De Coco (NDC) for advanced wound dressing applications. Utilizing the solution casting method, biocomposite films are developed using polyvinyl alcohol (PVA) with varied bio-filler c...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
John Wiley & Sons, Inc.
2025
|
| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/43955/ http://umpir.ump.edu.my/id/eprint/43955/1/Development%20of%20Bioactive%20Patches%20From%20Aloe%20Vera%20and%20Nata%20De%20Coco%20for%20Wound%20Dressing%20Applications.pdf |
| _version_ | 1848826998395240448 |
|---|---|
| author | Siti Maznah, Kabeb Nurlin, Abu Samah Nurjannah, Salim Farah Hanani, Zulkifli |
| author_facet | Siti Maznah, Kabeb Nurlin, Abu Samah Nurjannah, Salim Farah Hanani, Zulkifli |
| author_sort | Siti Maznah, Kabeb |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | This study focuses on the development and characterization of bioactive patches derived from Aloe Vera (AV) and Nata De Coco (NDC) for advanced wound dressing applications. Utilizing the solution casting method, biocomposite films are developed using polyvinyl alcohol (PVA) with varied
bio-filler content (2%−10%) w/w. Fourier-transform infrared (FTIR) analysis confirms the miscibility and compatibility of PVA and bio-fillers via intermolecular hydrogen bonding. PVA/NDC10 demonstrates the highest water-holding capacity (WHC), exhibiting an increase from 157.17% (neat
PVA) to 286.01%, resulting in an 82.0% enhancement. Conversely, increasing NDC content leads to a gradual decrease in tensile strength. Notably, the hybrid biocomposite film (PVA/AV/NDC) shows a significant 20.82% improvement in tensile strength, reaching 30.79 MPa. The study underscores the promise of AV and NDC bioactive patches for advanced wound dressing. Additionally, the hybrid approach shows synergistic improvements in water retention and mechanical strength, offering a comprehensive solution for effective wound management. |
| first_indexed | 2025-11-15T03:53:43Z |
| format | Article |
| id | ump-43955 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T03:53:43Z |
| publishDate | 2025 |
| publisher | John Wiley & Sons, Inc. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-439552025-07-01T07:20:08Z http://umpir.ump.edu.my/id/eprint/43955/ Development of bioactive patches from aloe vera and Nata De Coco for wound dressing applications Siti Maznah, Kabeb Nurlin, Abu Samah Nurjannah, Salim Farah Hanani, Zulkifli HD Industries. Land use. Labor TP Chemical technology This study focuses on the development and characterization of bioactive patches derived from Aloe Vera (AV) and Nata De Coco (NDC) for advanced wound dressing applications. Utilizing the solution casting method, biocomposite films are developed using polyvinyl alcohol (PVA) with varied bio-filler content (2%−10%) w/w. Fourier-transform infrared (FTIR) analysis confirms the miscibility and compatibility of PVA and bio-fillers via intermolecular hydrogen bonding. PVA/NDC10 demonstrates the highest water-holding capacity (WHC), exhibiting an increase from 157.17% (neat PVA) to 286.01%, resulting in an 82.0% enhancement. Conversely, increasing NDC content leads to a gradual decrease in tensile strength. Notably, the hybrid biocomposite film (PVA/AV/NDC) shows a significant 20.82% improvement in tensile strength, reaching 30.79 MPa. The study underscores the promise of AV and NDC bioactive patches for advanced wound dressing. Additionally, the hybrid approach shows synergistic improvements in water retention and mechanical strength, offering a comprehensive solution for effective wound management. John Wiley & Sons, Inc. 2025 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/43955/1/Development%20of%20Bioactive%20Patches%20From%20Aloe%20Vera%20and%20Nata%20De%20Coco%20for%20Wound%20Dressing%20Applications.pdf Siti Maznah, Kabeb and Nurlin, Abu Samah and Nurjannah, Salim and Farah Hanani, Zulkifli (2025) Development of bioactive patches from aloe vera and Nata De Coco for wound dressing applications. Macromolecular Symposia, 414 (1). pp. 1-6. ISSN 1521-3900. (Published) https://doi.org/10.1002/masy.202300235 10.1002/masy.202300235 |
| spellingShingle | HD Industries. Land use. Labor TP Chemical technology Siti Maznah, Kabeb Nurlin, Abu Samah Nurjannah, Salim Farah Hanani, Zulkifli Development of bioactive patches from aloe vera and Nata De Coco for wound dressing applications |
| title | Development of bioactive patches from aloe vera and Nata De Coco for wound dressing applications |
| title_full | Development of bioactive patches from aloe vera and Nata De Coco for wound dressing applications |
| title_fullStr | Development of bioactive patches from aloe vera and Nata De Coco for wound dressing applications |
| title_full_unstemmed | Development of bioactive patches from aloe vera and Nata De Coco for wound dressing applications |
| title_short | Development of bioactive patches from aloe vera and Nata De Coco for wound dressing applications |
| title_sort | development of bioactive patches from aloe vera and nata de coco for wound dressing applications |
| topic | HD Industries. Land use. Labor TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/43955/ http://umpir.ump.edu.my/id/eprint/43955/ http://umpir.ump.edu.my/id/eprint/43955/ http://umpir.ump.edu.my/id/eprint/43955/1/Development%20of%20Bioactive%20Patches%20From%20Aloe%20Vera%20and%20Nata%20De%20Coco%20for%20Wound%20Dressing%20Applications.pdf |