Therapeutic potential inhibitor for dipeptidyl peptidase IV in diabetic type 2: In silico approaches
Diabetes mellitus (DM) is a metabolic disease marked by an excessive rise in blood sugar (glucose) levels caused by a partial or total absence of insulin production, combined with alterations in the metabolism of proteins, lipids, and carbohydrates. The International Diabetes Federation estimates th...
| Main Authors: | Roney, Miah, Dubey, Amit, Nazim Uddin, Mohammed Nazim, Issahaku, Abdul Rashid, Tufail, Aisha, Tufail, Nasir, Wilhelm, Anke, Mohd Fadhlizil Fasihi, Mohd Aluwi |
|---|---|
| Format: | Article |
| Language: | English English |
| Published: |
Springer Science and Business Media Deutschland GmbH
2025
|
| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/43863/ http://umpir.ump.edu.my/id/eprint/43863/1/Therapeutic%20potential%20inhibitor%20for%20dipeptidyl%20peptidase%20IV.pdf http://umpir.ump.edu.my/id/eprint/43863/2/Therapeutic%20potential%20inhibitor%20for%20dipeptidyl%20peptidase%20IV%20in%20diabetic%20type%202_In%20silico%20approaches_ABS.pdf |
Similar Items
Insights from in silico exploration of major curcumin analogs targeting human dipeptidyl peptidase IV
by: Roney, Miah, et al.
Published: (2024)
by: Roney, Miah, et al.
Published: (2024)
Repurposing of dipeptidyl peptidase FDA-approved drugs in Alzheimer's disease using network pharmacology and in-silico approaches
by: Roney, Miah, et al.
Published: (2025)
by: Roney, Miah, et al.
Published: (2025)
Alkaloids from Popowia perakensis and their dipeptidyl peptidase IV(DPP IV) inhibitors
by: Syed Abdul Azziz, Saripah Salbiah, et al.
Published: (2019)
by: Syed Abdul Azziz, Saripah Salbiah, et al.
Published: (2019)
Alkaloids from Popowia perakensis King and their potential as Dipeptidyl peptidase IV (DPP IV) inhibitors
by: Syed Abdul Azziz, Saripah Salbiah, et al.
Published: (2019)
by: Syed Abdul Azziz, Saripah Salbiah, et al.
Published: (2019)
Exploration of leads from bis-indole based triazine derivatives targeting human aldose reductase in diabetic type 2: In-silico approaches
by: Roney, Miah, et al.
Published: (2025)
by: Roney, Miah, et al.
Published: (2025)
Computational screening of FDA-approved hepatitis c drugs for inhibition of VEGFR2 in liver cancer
by: Roney, Miah, et al.
Published: (2024)
by: Roney, Miah, et al.
Published: (2024)
Identification of potent new brain cancer EGFR inhibitor from usimine A and usimine B: computer-aided drug design perspective
by: Roney, Miah, et al.
Published: (2024)
by: Roney, Miah, et al.
Published: (2024)
In silico analysis for discovery of dengue virus inhibitor from natural compounds
by: Roney, Miah, et al.
Published: (2022)
by: Roney, Miah, et al.
Published: (2022)
Pharmacophore-based virtual screening and in-silico study of natural products as potential DENV-2 RdRp inhibitors
by: Miah, Roney, et al.
Published: (2023)
by: Miah, Roney, et al.
Published: (2023)
Inhibitory effect of Sinapic acid derivatives targeting structural and non-structural proteins of dengue virus serotype 2 An in-silico assessment
by: Roney, Miah, et al.
Published: (2023)
by: Roney, Miah, et al.
Published: (2023)
The importance of in-silico studies in drug discovery
by: Roney, Miah, et al.
Published: (2024)
by: Roney, Miah, et al.
Published: (2024)
In-silico Studies of Usnic Acid against DENV-3 Methyltransferase
by: Roney, Miah, et al.
Published: (2023)
by: Roney, Miah, et al.
Published: (2023)
Comprehending the pharmacological mechanism of marine phenolic acids in bladder cancer therapy against matrix metalloproteinase 9 protein by integrated network pharmacology and in-silico approaches
by: Roney, Miah, et al.
Published: (2024)
by: Roney, Miah, et al.
Published: (2024)
Dipeptidyl peptidase IV (DPP IV) inhibitory activity screening of Momordica charantia, Taraxacum officinale and Trigonella foenum-graecumextracts in vitro
by: Perumal, N., et al.
Published: (2016)
by: Perumal, N., et al.
Published: (2016)
In silico exploration of Isoxazole derivatives of usnic acid: novel therapeutic prospects against α-Amylase for diabetes treatment
by: Roney, Miah, et al.
Published: (2024)
by: Roney, Miah, et al.
Published: (2024)
The effect of bioactive polyphenols from anacardium occidentale linn. Leaves on α-amylase and dipeptidyl peptidase iv activities
by: Abdullah Thaidi, Nur Imanina, et al.
Published: (2019)
by: Abdullah Thaidi, Nur Imanina, et al.
Published: (2019)
Design and in-silico studies of abacavir analogues as Anti-DENV-2 NS5 methyltransferase
by: Roney, Miah, et al.
Published: (2025)
by: Roney, Miah, et al.
Published: (2025)
Computational evaluation of quinones of Nigella sativa L. as potential inhibitor of dengue virus NS5
by: Roney, Miah, et al.
Published: (2023)
by: Roney, Miah, et al.
Published: (2023)
Identification of dipeptidyl-peptidase 4 (DPP-4) inhibitors from miracle berry fruit (Synsepalum dulcificum) extract
by: Hamsah Zollapi, Nuraliana Najwa, et al.
Published: (2023)
by: Hamsah Zollapi, Nuraliana Najwa, et al.
Published: (2023)
Neurological sequelae of post-COVID-19 fatigue: a narrative review of dipeptidyl peptidase IV-mediated cerebrovascular complications
by: Che Mohd Nassir, Che Mohd Nasril, et al.
Published: (2024)
by: Che Mohd Nassir, Che Mohd Nasril, et al.
Published: (2024)
Mefenamic acid inhibit transforming growth factor-beta type-1: Repurposing anti-inflammatory drugs in wound healing using in-silico approaches
by: Roney, Miah, et al.
Published: (2023)
by: Roney, Miah, et al.
Published: (2023)
Clinical and genetic associations of dipeptidyl peptidase-4 inhibitor treatment response in type 2 diabetes / Jazlina Liza Jamaluddin
by: Jazlina Liza , Jamaluddin
Published: (2017)
by: Jazlina Liza , Jamaluddin
Published: (2017)
In-silico design of curcumin analogs as potential inhibitors of dengue virus NS2B/NS3 protease
by: Roney, Miah, et al.
Published: (2023)
by: Roney, Miah, et al.
Published: (2023)
In silico evaluation of usnic acid derivatives to discover potential antibacterial drugs against DNA gyrase B and DNA topoisomerase IV
by: Miah, Roney, et al.
Published: (2023)
by: Miah, Roney, et al.
Published: (2023)
Phenolic compounds of Theobroma cacao L. show potential against dengue RdRp protease enzyme inhibition by In-silico docking, DFT study, MD simulation and MMGBSA calculation
by: Moyeenul Huq, A. K. M., et al.
Published: (2024)
by: Moyeenul Huq, A. K. M., et al.
Published: (2024)
In silico identification of PPARγ agonists from diffractaic acid analogs in prostate cancer: a comprehensive computational approach
by: Roney, Miah, et al.
Published: (2025)
by: Roney, Miah, et al.
Published: (2025)
Identifying catalytic residues for peptidases: in silico perspective
by: Muhamad Bunnori, Noraslinda
Published: (2011)
by: Muhamad Bunnori, Noraslinda
Published: (2011)
The role of bioactive compounds from Anacardium Occidentale Linn. On alpha amylase and dipeptidyl peptidase IV as antidiabetic agent for type 2 diabetes mellitus management
by: Abdullah Thaidi, Nur Imanina, et al.
Published: (2018)
by: Abdullah Thaidi, Nur Imanina, et al.
Published: (2018)
The role of bioactive polyphenols from anacardium occidentale linn. leaves on α-amylase and dipeptidyl peptidase iv activities for type 2 diabetes mellitus management
by: Haron, Normah, et al.
Published: (2018)
by: Haron, Normah, et al.
Published: (2018)
Identification of dipeptidyl peptidase-4 inhibitory compounds of Paederia foetida twigs by nuclear magnetic resonance metabolomics, in silico models, and liquid chromatography–mass spectrometry profiling
by: Tan, Dai Chuan, et al.
Published: (2023)
by: Tan, Dai Chuan, et al.
Published: (2023)
Computer-aided anti-cancer drug discovery of EGFR protein based on virtual screening of drug bank, ADMET, docking, DFT and molecular dynamic simulation studies
by: Roney, Miah, et al.
Published: (2023)
by: Roney, Miah, et al.
Published: (2023)
An in-silico approach to evaluate bioactive molecules of aloe vera leaf extracts in inhibiting the glycogen synthase kinase-3β (GSK3-β) protein for faster diabetic wound healing potential
by: Roney, Miah, et al.
Published: (2024)
by: Roney, Miah, et al.
Published: (2024)
Virtual screening of pyrazole derivatives of usnic acid as new class of anti-hyperglycemic agents against PPARγ agonists
by: Roney, Miah, et al.
Published: (2023)
by: Roney, Miah, et al.
Published: (2023)
Polypharmacological assessment of amoxicillin and its analogues against the bacterial DNA gyrase B using molecular docking, DFT and molecular dynamics simulation
by: Miah, Roney, et al.
Published: (2023)
by: Miah, Roney, et al.
Published: (2023)
Discovery of COVID-19 protein inhibitors in phenolic acids of azadirachta indica (neem) using docking and pharmacokinetics
by: Roney, Miah, et al.
Published: (2024)
by: Roney, Miah, et al.
Published: (2024)
Diabetic wound healing of aloe vera major phytoconstituents through TGF-b1 suppression via in-silico docking, molecular dynamic simulation and pharmacokinetic studies
by: Roney, Miah, et al.
Published: (2023)
by: Roney, Miah, et al.
Published: (2023)
Outcome evaluation of dipeptidyl peptidase 4 (DPP4) inhibitors and its combination on glycemic control of type 2 diabetes mellitus patients at Putrajaya Hospital / Nurhamizah Noor Rahim
by: Noor Rahim, Nurhamizah
Published: (2016)
by: Noor Rahim, Nurhamizah
Published: (2016)
Association of genetic polymorphisms of dipeptidyl peptidase-4 with Type 2 Diabetes Mellitus in Malaysian subjects / Radwan Hamoud Ali Ahmed
by: Radwan Hamoud, Ali Ahmed
Published: (2017)
by: Radwan Hamoud, Ali Ahmed
Published: (2017)
Pharmacophore-based molecular docking and in-silico study of novel usnic acid derivatives as avian influenza A (H7N9) inhibitor
by: Roney, Miah, et al.
Published: (2022)
by: Roney, Miah, et al.
Published: (2022)
Comparative studies of dipeptidyl peptidase 4 inhibitor vs sulphonylurea among Muslim Type 2 diabetes patients who fast in the month of Ramadan: A systematic review and meta-analysis
by: Loh, Huai Heng, et al.
Published: (2016)
by: Loh, Huai Heng, et al.
Published: (2016)
Similar Items
-
Insights from in silico exploration of major curcumin analogs targeting human dipeptidyl peptidase IV
by: Roney, Miah, et al.
Published: (2024) -
Repurposing of dipeptidyl peptidase FDA-approved drugs in Alzheimer's disease using network pharmacology and in-silico approaches
by: Roney, Miah, et al.
Published: (2025) -
Alkaloids from Popowia perakensis and their dipeptidyl peptidase IV(DPP IV) inhibitors
by: Syed Abdul Azziz, Saripah Salbiah, et al.
Published: (2019) -
Alkaloids from Popowia perakensis King and their potential as Dipeptidyl peptidase IV (DPP IV) inhibitors
by: Syed Abdul Azziz, Saripah Salbiah, et al.
Published: (2019) -
Exploration of leads from bis-indole based triazine derivatives targeting human aldose reductase in diabetic type 2: In-silico approaches
by: Roney, Miah, et al.
Published: (2025)