Design, synthesis, structural characterization, cytotoxicity and computational studies of Usnic acid derivative as potential anti-breast cancer agent against MCF7 and T47D cell lines

Design, synthesis, structural characterization, cytotoxicity and computational studies of Usnic acid derivative as potential anti-breast cancer agent against MCF7 and T47D cell lines

Development of novel inhibitors is necessary to counteract the rising prevalence of breast cancer (BC) in women in recent years, as evidenced by the side-effect profiles of a few clinically approved inhibitors. In this study, the usnic acid derivative (UA1) was synthesized due to the effectiveness o...

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Bibliographic Details
Main Authors: Roney, Miah, Wong, Kelvin Khai Voon, Uddin, Md. Nazim, Rullah, Kamal, Septama, Abdi Wira, Antika, Lucia Dwi, Mohd Fadhlizil Fasihi, Mohd Aluwi
Format: Article
Language:English
Published: Elsevier Ltd 2025
Subjects:
HD Industries. Land use. Labor
T Technology (General)
Online Access:http://umpir.ump.edu.my/id/eprint/43154/
http://umpir.ump.edu.my/id/eprint/43154/1/Design%2C%20synthesis%2C%20structural%20characterization%2C%20cytotoxicity%20and%20computational%20studies%20of%20Usnic%20acid%20derivative%20as%20potential%20anti-breast%20cancer%20agent%20against%20MCF7%20and%20T47D%20cell%20lines.pdf

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