Discovery of COVID-19 protein inhibitors in phenolic acids of azadirachta indica (neem) using docking and pharmacokinetics

QR Code

Discovery of COVID-19 protein inhibitors in phenolic acids of azadirachta indica (neem) using docking and pharmacokinetics

COVID-19, a viral infection caused by the coronavirus SARS-CoV-2, is one of the world's most challenging diseases to cure. The fact that COVID-19 does not currently have any pharmaceutical treatments means that a concentrated effort must be made to discover the muchneeded remedies for this illn...

Full description

Bibliographic Details
Main Authors:	Roney, Miah, Huq, AKM Moyeenul, Mohd Fadhlizil Fasihi, Mohd Aluwi
Format:	Article
Language:	English
Published:	Thammasat University 2024
Subjects:	HD Industries. Land use. Labor
Online Access:	http://umpir.ump.edu.my/id/eprint/43153/ http://umpir.ump.edu.my/id/eprint/43153/1/Discovery%20of%20COVID-19%20protein%20inhibitors%20in%20phenolic%20acids%20of%20azadirachta%20indica%20%28neem%29%20using%20docking%20and%20pharmacokinetics.pdf

Similar Items

Anti-diabetic activity of phloretin against maltase-glucoamylase using docking, pharmacokinetics and pharmacophore studies
by: Roney, Miah, et al.
Published: (2023)

Effect of drying methods on phenolic contents of neem (Azadirachta indica) leaf powder
by: Sejali, S. N. F., et al.
Published: (2011)

Neem (Azadirachta indica) oil as an anthelmintic in goats
by: Nor Aslan, Nurul Aqidah, et al.
Published: (2010)

Chemical characterization and biological studies of Neem (Azadirachta Indica) extracts
by: Jessinta, Sandanasamy
Published: (2014)

In silico analysis for discovery of dengue virus inhibitor from natural compounds
by: Roney, Miah, et al.
Published: (2022)

Acetylcholinesterase studies as colonic pseudo-obstruction inhibitor on quercitrin from neem leaf extract (Azadirachta indica)
by: Abdul Ghani, Nur Hamizah, et al.
Published: (2023)

Molecular docking and drug-likeness study of nirmatrelvir as promising drug candidates of dengue virus NS2B-NS3 protease
by: Huq, A.K.M. Moyeenul, et al.
Published: (2023)

Production of lotion using neem (Azadirachta Indica A. Juss) extract
by: Ghazali, Norliza, et al.
Published: (2020)

The importance of in-silico studies in drug discovery
by: Roney, Miah, et al.
Published: (2024)

Fatty Acid Composition and Antibacterial Activity of Neem (Azadirachta indica) Seed Oil
by: Jessinta, Sandanasamy, et al.
Published: (2013)

Impact Of Geographic Variation On Physicochemical Properties Of Neem (Azadirachta Indica) Seed Oil
by: Sandanasamy, Jessinta, et al.
Published: (2014)

Deciphering the mechanism of usnic acid in type 2 diabetes treatment: A network pharmacology and molecular docking approach
by: Roney, Miah, et al.
Published: (2025)

Wound Healing Activity of Pyrazole-thiazole Derivatives of Curcumin Through the Docking, Pharmacokinetics, MD Simulation and MM/GBSA Approaches
by: Forid, Md Shaekh, et al.
Published: (2024)

Azadirachta Indica Extract (Neem) as skin solution soap / Mazni Musa... [et al.]
by: Musa, Mazni, et al.
Published: (2019)

Computer-aided anti-cancer drug discovery of EGFR protein based on virtual screening of drug bank, ADMET, docking, DFT and molecular dynamic simulation studies
by: Roney, Miah, et al.
Published: (2023)

Pharmacophore-based molecular docking and in-silico study of novel usnic acid derivatives as avian influenza A (H7N9) inhibitor
by: Roney, Miah, et al.
Published: (2022)

Molecular docking and in silico evaluation of phytochemicals of bioactive methanolic extract of Ipomoea mauritiana Jacq. as anti-bacterial agents
by: Roney, Miah, et al.
Published: (2022)

Development of process conditions to optimize the extraction of bio-disinfectant from Neem Leaf (Azadirachta Indica)
by: Jamal, Parveen, et al.
Published: (2012)

Antibacterial activity of neem (Azadirachta Indica) extracts against multiple drug resistant (MDR) bacteria
by: Ng , Yin Boon
Published: (2012)

Anti-fungal efficacy of aqueous leaf extracts Neem (Azadirachta indica) in the treatment of tap water
by: Habberrih, Salah Omar Abdulali, et al.
Published: (2022)

Antibacterial activity of neem (Azadirachta indica) leaves on Vibrio spp. isolated from cultured shrimp.
by: Banarjee, Sanjoy, et al.
Published: (2013)

In-silico design of curcumin analogs as potential inhibitors of dengue virus NS2B/NS3 protease
by: Roney, Miah, et al.
Published: (2023)

Morphological and Molecular Characterisation of Ethanolic Neem (Azadirachta Indica) Leaf Extract In an in Vivo Breast Cancer Model
by: Lam, Tsuey Peng
Published: (2007)

Biology And Population Dynamics Of Mango Flower Thrips (Thysanoptera) And Effectiveness Of Neem (Azadirachta Indica) Oil For Their Control
by: Aliakbarpour, Hamaseh
Published: (2011)

Investigation of ethanol, acetone and aqueous azadirachta indica A. Juss (NEEM) extracts against plasmodium falciparum
by: Ghazali, Siti Zulaiha
Published: (2022)

Diabetic wound healing of aloe vera major phytoconstituents through TGF-b1 suppression via in-silico docking, molecular dynamic simulation and pharmacokinetic studies
by: Roney, Miah, et al.
Published: (2023)

Virtual screening-based identification of Potent DENV-3 RdRp protease inhibitors via in-house usnic acid derivative database
by: Roney, Miah, et al.
Published: (2021)

Curcumin, a bioactive compound of Turmeric (Curcuma longa) and its derivatives as α-amylase and α-glucosidase inhibitors
by: Roney, Miah, et al.
Published: (2024)

In-silico Studies of Usnic Acid against DENV-3 Methyltransferase
by: Roney, Miah, et al.
Published: (2023)

Polypharmacological assessment of amoxicillin and its analogues against the bacterial DNA gyrase B using molecular docking, DFT and molecular dynamics simulation
by: Miah, Roney, et al.
Published: (2023)

The potential of neem extract, azadirachta indica as natural pesticide on ants, ochetellus spp. / Noor Faizatul Asyikin Razaha
by: Razaha, Noor Faizatul Asyikin
Published: (2017)

Larvicidal properties of extracts from different parts of neem (Azadirachta Indica) against Aedes Aegypti mosquitoes' larvae
by: Jessinta, Sandanasamy
Published: (2012)

Extract of Azadirachta indica (Neem) leaf induces apoptosis in 4T1 breast cancer BALB/c mice.
by: Othman, Fauziah, et al.
Published: (2011)

Potential Immunomodulating Activity Of Neem (Azadirachta Indica) Leaf Extracts And Its Bioactive Compound N-Acetylglucosamine In Mice
by: Kumar, Venugopalan Santhosh
Published: (2018)

Qualitative dataset on UPLC-QTOF/MS tentative identification of phytochemicals from bioactive extract of Ipomoea mauritiana Jacq.
by: Alam, Istiak, et al.
Published: (2021)

Kinetic, isotherm, and possible mechanism of Pb(II) ion adsorption onto xanthated neem (Azadirachta indica) leaf powder
by: Mardhiah Ismail,, et al.

Effects of neem oil, Azadirachta indica A. juss on growth and survival of bagworm, Metisa plana (LEPIDOPTERA: PSYCHIDAE) LARVAE
by: Siti Nurulhidayah Ahmad,, et al.
Published: (2024)

Antibacterial activity and toxicity assay of biosynthesized silver nanoparticles by neem [azadirachta indica] leaves extract / Nur Amira Sariman
by: Sariman, Nur Amira
Published: (2020)

Effects of neem oil, Azadirachta indica a. juss on growth and survival of bagworm, Metisa plana (lepidoptera: psychidae) larvae
by: Ahmad, Siti Nurulhidayah, et al.
Published: (2024)

Concerns regarding SARS-CoV-2 JN.1 mutations should be raised
by: Roney, Miah, et al.
Published: (2024)