Eco-friendly and efficient extraction of phenolic compounds from Commiphora gileadensis bark using microwave-assisted extraction
Commiphora gileadensis (C. gileadensis) is a medicinal plant with a variety of biological activity; its bark has several therapeutic potentials, including the treatment of wounds, inflammatory diseases, and treating bacterial infections. This study utilized microwave-assisted extraction (MAE) to opt...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English English |
| Published: |
Elsevier
2024
|
| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/42360/ http://umpir.ump.edu.my/id/eprint/42360/1/Eco-friendly%20and%20efficient%20extraction%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark.pdf http://umpir.ump.edu.my/id/eprint/42360/2/Eco-friendly%20and%20efficient%20extraction%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark%20using%20microwave-assisted%20extraction.pdf |
| _version_ | 1848826590010540032 |
|---|---|
| author | Aiman A., Mokaizh Nour, Abdurahman Hamid Ali, Gomaa A.M. Ukaegbu, Chinonso Ishmael Hawege, Emsalem Faraj |
| author_facet | Aiman A., Mokaizh Nour, Abdurahman Hamid Ali, Gomaa A.M. Ukaegbu, Chinonso Ishmael Hawege, Emsalem Faraj |
| author_sort | Aiman A., Mokaizh |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Commiphora gileadensis (C. gileadensis) is a medicinal plant with a variety of biological activity; its bark has several therapeutic potentials, including the treatment of wounds, inflammatory diseases, and treating bacterial infections. This study utilized microwave-assisted extraction (MAE) to optimize the recovery and phenolic components of the ethanolic extracts of C. gileadensis bark. Different MAE process parameters (microwave power, irradiation time, sample/solvent ratio, extraction temperature, and solvent (ethanol) concentration) were studied for their impacts on the extraction process using One-Factor-At-a-Time (OFAT) method. The extracts were further characterized for the presence of different phytochemicals using Gas Chromatography-Mass Spectroscopy (FC-MS) and Fourier Transform Infrared Spectroscopy (FTIR) analyses. The experimental findings revealed that the maximum extraction yield, total phenolic content (TPC), and total flavonoid content (TFC) of the ethanolic extract of the of C. gileadensis bark using MAE process were 39.40 ± 0.47 w/w%, 166.41 ± 3.97 mg GAE/g d.w., and 52.83 ± 2.95 mg QE/g d.w., respectively. Furthermore, 30 phenolic constituents were discovered in the extract of C. gileadensis bark for the first time, and these compounds showed good in vitro antioxidant activity. Hence, MAE is a suitable technique for efficient and green extraction of different groups of phytochemicals of pharmaceutical importance from the bark of C. gileadensis. |
| first_indexed | 2025-11-15T03:47:14Z |
| format | Article |
| id | ump-42360 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T03:47:14Z |
| publishDate | 2024 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-423602024-08-14T08:38:30Z http://umpir.ump.edu.my/id/eprint/42360/ Eco-friendly and efficient extraction of phenolic compounds from Commiphora gileadensis bark using microwave-assisted extraction Aiman A., Mokaizh Nour, Abdurahman Hamid Ali, Gomaa A.M. Ukaegbu, Chinonso Ishmael Hawege, Emsalem Faraj TP Chemical technology Commiphora gileadensis (C. gileadensis) is a medicinal plant with a variety of biological activity; its bark has several therapeutic potentials, including the treatment of wounds, inflammatory diseases, and treating bacterial infections. This study utilized microwave-assisted extraction (MAE) to optimize the recovery and phenolic components of the ethanolic extracts of C. gileadensis bark. Different MAE process parameters (microwave power, irradiation time, sample/solvent ratio, extraction temperature, and solvent (ethanol) concentration) were studied for their impacts on the extraction process using One-Factor-At-a-Time (OFAT) method. The extracts were further characterized for the presence of different phytochemicals using Gas Chromatography-Mass Spectroscopy (FC-MS) and Fourier Transform Infrared Spectroscopy (FTIR) analyses. The experimental findings revealed that the maximum extraction yield, total phenolic content (TPC), and total flavonoid content (TFC) of the ethanolic extract of the of C. gileadensis bark using MAE process were 39.40 ± 0.47 w/w%, 166.41 ± 3.97 mg GAE/g d.w., and 52.83 ± 2.95 mg QE/g d.w., respectively. Furthermore, 30 phenolic constituents were discovered in the extract of C. gileadensis bark for the first time, and these compounds showed good in vitro antioxidant activity. Hence, MAE is a suitable technique for efficient and green extraction of different groups of phytochemicals of pharmaceutical importance from the bark of C. gileadensis. Elsevier 2024 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/42360/1/Eco-friendly%20and%20efficient%20extraction%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark.pdf pdf en http://umpir.ump.edu.my/id/eprint/42360/2/Eco-friendly%20and%20efficient%20extraction%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark%20using%20microwave-assisted%20extraction.pdf Aiman A., Mokaizh and Nour, Abdurahman Hamid and Ali, Gomaa A.M. and Ukaegbu, Chinonso Ishmael and Hawege, Emsalem Faraj (2024) Eco-friendly and efficient extraction of phenolic compounds from Commiphora gileadensis bark using microwave-assisted extraction. Journal of Industrial and Engineering Chemistry. pp. 1-8. ISSN 1226-086X. (In Press / Online First) (In Press / Online First) https://doi.org/10.1016/j.jiec.2024.07.038 10.1016/j.jiec.2024.07.038 |
| spellingShingle | TP Chemical technology Aiman A., Mokaizh Nour, Abdurahman Hamid Ali, Gomaa A.M. Ukaegbu, Chinonso Ishmael Hawege, Emsalem Faraj Eco-friendly and efficient extraction of phenolic compounds from Commiphora gileadensis bark using microwave-assisted extraction |
| title | Eco-friendly and efficient extraction of phenolic compounds from Commiphora gileadensis bark using microwave-assisted extraction |
| title_full | Eco-friendly and efficient extraction of phenolic compounds from Commiphora gileadensis bark using microwave-assisted extraction |
| title_fullStr | Eco-friendly and efficient extraction of phenolic compounds from Commiphora gileadensis bark using microwave-assisted extraction |
| title_full_unstemmed | Eco-friendly and efficient extraction of phenolic compounds from Commiphora gileadensis bark using microwave-assisted extraction |
| title_short | Eco-friendly and efficient extraction of phenolic compounds from Commiphora gileadensis bark using microwave-assisted extraction |
| title_sort | eco-friendly and efficient extraction of phenolic compounds from commiphora gileadensis bark using microwave-assisted extraction |
| topic | TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/42360/ http://umpir.ump.edu.my/id/eprint/42360/ http://umpir.ump.edu.my/id/eprint/42360/ http://umpir.ump.edu.my/id/eprint/42360/1/Eco-friendly%20and%20efficient%20extraction%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark.pdf http://umpir.ump.edu.my/id/eprint/42360/2/Eco-friendly%20and%20efficient%20extraction%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark%20using%20microwave-assisted%20extraction.pdf |