Extraction and characterization of phenolic compounds from Commiphora gileadensis bark using ultrasonic-assisted extraction
Developing nations across the globe place significant importance on ensuring the complete protection, efficacy, and quality of herbal products and medicinal plants. Among these beneficial plants, Commiphora gileadensis stands out due to its diverse array of biological activities. The bark of this pl...
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| Format: | Article |
| Language: | English English |
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Elsevier Ltd
2024
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| Online Access: | http://umpir.ump.edu.my/id/eprint/42358/ http://umpir.ump.edu.my/id/eprint/42358/1/Extraction%20and%20characterization%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark_ABST.pdf http://umpir.ump.edu.my/id/eprint/42358/2/Extraction%20and%20characterization%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark.pdf |
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| author | Aiman A., Mokaizh Nour, Abdurahman Hamid Rosli, Mohd Yunus |
| author_facet | Aiman A., Mokaizh Nour, Abdurahman Hamid Rosli, Mohd Yunus |
| author_sort | Aiman A., Mokaizh |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Developing nations across the globe place significant importance on ensuring the complete protection, efficacy, and quality of herbal products and medicinal plants. Among these beneficial plants, Commiphora gileadensis stands out due to its diverse array of biological activities. The bark of this plant species offers numerous therapeutic advantages, including its potential for treating wounds, inflammatory conditions, and bacterial infections. To explore the process of extraction of biologically active components, this study employed ultrasonic-assisted extraction (UAE) on ethanolic extracts of C. gileadensis bark. Various variables of UAE process, such as ultrasonic frequency, extraction time, sample-to-solvent ratio, and ethanol concentration, were carefully investigated via the ‘’One-Factor-At-a-Time (OFAT)’’ method to understand their individual impacts on the extraction process. The obtained extracts underwent further analysis to identify the presence of different phytochemicals, employing techniques such as ‘’Gas Chromatography-Mass Spectroscopy (GC-MS) and Fourier Transform Infrared Spectroscopy (FTIR)’’. The experimental results demonstrated that the UAE process yielded promising outcomes, with the maximum extraction yields, total phenolic content (TPC), and total flavonoids content (TFC) of the ethanolic extract from C. gileadensis bark reaching 37.60 ± 0.31 %, 149.75 ± 3.23 mg GAE/g d.w., and 44.84 ± 3.02 mg QE/g d.w., respectively. Additionally, this study successfully identified a total of 30 phenolic compounds present in the C. gileadensis bark extract for the first time, highlighting the efficacy of UAE as a suitable method for efficiently extracting various groups of phytochemicals from the bark of C. gileadensis. |
| first_indexed | 2025-11-15T03:47:13Z |
| format | Article |
| id | ump-42358 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T03:47:13Z |
| publishDate | 2024 |
| publisher | Elsevier Ltd |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-423582024-08-14T07:15:21Z http://umpir.ump.edu.my/id/eprint/42358/ Extraction and characterization of phenolic compounds from Commiphora gileadensis bark using ultrasonic-assisted extraction Aiman A., Mokaizh Nour, Abdurahman Hamid Rosli, Mohd Yunus QD Chemistry TP Chemical technology Developing nations across the globe place significant importance on ensuring the complete protection, efficacy, and quality of herbal products and medicinal plants. Among these beneficial plants, Commiphora gileadensis stands out due to its diverse array of biological activities. The bark of this plant species offers numerous therapeutic advantages, including its potential for treating wounds, inflammatory conditions, and bacterial infections. To explore the process of extraction of biologically active components, this study employed ultrasonic-assisted extraction (UAE) on ethanolic extracts of C. gileadensis bark. Various variables of UAE process, such as ultrasonic frequency, extraction time, sample-to-solvent ratio, and ethanol concentration, were carefully investigated via the ‘’One-Factor-At-a-Time (OFAT)’’ method to understand their individual impacts on the extraction process. The obtained extracts underwent further analysis to identify the presence of different phytochemicals, employing techniques such as ‘’Gas Chromatography-Mass Spectroscopy (GC-MS) and Fourier Transform Infrared Spectroscopy (FTIR)’’. The experimental results demonstrated that the UAE process yielded promising outcomes, with the maximum extraction yields, total phenolic content (TPC), and total flavonoids content (TFC) of the ethanolic extract from C. gileadensis bark reaching 37.60 ± 0.31 %, 149.75 ± 3.23 mg GAE/g d.w., and 44.84 ± 3.02 mg QE/g d.w., respectively. Additionally, this study successfully identified a total of 30 phenolic compounds present in the C. gileadensis bark extract for the first time, highlighting the efficacy of UAE as a suitable method for efficiently extracting various groups of phytochemicals from the bark of C. gileadensis. Elsevier Ltd 2024-07-17 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/42358/1/Extraction%20and%20characterization%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark_ABST.pdf pdf en http://umpir.ump.edu.my/id/eprint/42358/2/Extraction%20and%20characterization%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark.pdf Aiman A., Mokaizh and Nour, Abdurahman Hamid and Rosli, Mohd Yunus (2024) Extraction and characterization of phenolic compounds from Commiphora gileadensis bark using ultrasonic-assisted extraction. Pharmacological Research - Natural Products, 4 (100066). pp. 1-8. ISSN 2950-1997. (Published) https://doi.org/10.1016/j.prenap.2024.100066 https://doi.org/10.1016/j.prenap.2024.100066 |
| spellingShingle | QD Chemistry TP Chemical technology Aiman A., Mokaizh Nour, Abdurahman Hamid Rosli, Mohd Yunus Extraction and characterization of phenolic compounds from Commiphora gileadensis bark using ultrasonic-assisted extraction |
| title | Extraction and characterization of phenolic compounds from Commiphora gileadensis bark using ultrasonic-assisted extraction |
| title_full | Extraction and characterization of phenolic compounds from Commiphora gileadensis bark using ultrasonic-assisted extraction |
| title_fullStr | Extraction and characterization of phenolic compounds from Commiphora gileadensis bark using ultrasonic-assisted extraction |
| title_full_unstemmed | Extraction and characterization of phenolic compounds from Commiphora gileadensis bark using ultrasonic-assisted extraction |
| title_short | Extraction and characterization of phenolic compounds from Commiphora gileadensis bark using ultrasonic-assisted extraction |
| title_sort | extraction and characterization of phenolic compounds from commiphora gileadensis bark using ultrasonic-assisted extraction |
| topic | QD Chemistry TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/42358/ http://umpir.ump.edu.my/id/eprint/42358/ http://umpir.ump.edu.my/id/eprint/42358/ http://umpir.ump.edu.my/id/eprint/42358/1/Extraction%20and%20characterization%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark_ABST.pdf http://umpir.ump.edu.my/id/eprint/42358/2/Extraction%20and%20characterization%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark.pdf |