Computational fluid dynamics of patient-specific coronary artery during stent treatment
Coronary artery disease is usually treated using stent treatment. However, restenosis is one of the major limitations of using stent. Local hemodynamics can be the main indicator of the occurrence of restenosis. In this project, a computational fluid dynamics (CFD) analysis is performed on a stented...
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| Format: | Conference or Workshop Item |
| Language: | English English |
| Published: |
IET
2022
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| Online Access: | http://umpir.ump.edu.my/id/eprint/41971/ http://umpir.ump.edu.my/id/eprint/41971/1/Computational%20fluid%20dynamics%20of%20patient-specific%20coronary%20artery_ABST.pdf http://umpir.ump.edu.my/id/eprint/41971/2/Computational%20fluid%20dynamics%20of%20patient-specific%20coronary%20artery.pdf |
| _version_ | 1848826483632504832 |
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| author | Nur Syuhada, Che Amdilah Lau, Yu Shi Liew, Yih Miin Wan Naimah, Wan Ab Naim Mohd Jamil, Mohamed Mokhtarudin |
| author_facet | Nur Syuhada, Che Amdilah Lau, Yu Shi Liew, Yih Miin Wan Naimah, Wan Ab Naim Mohd Jamil, Mohamed Mokhtarudin |
| author_sort | Nur Syuhada, Che Amdilah |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Coronary artery disease is usually treated using stent treatment. However, restenosis is one of the major limitations of using stent. Local hemodynamics can be the main indicator of the occurrence of restenosis. In this project, a computational fluid dynamics (CFD) analysis is performed on a stented coronary artery patient with a 12-month follow-up post stent in order to determine the potential occurrence of restenosis in the patient. An OCT image of the coronary artery is taken and ethically approved from Universiti Malaya Medical Centre (UMMC). Firstly, a 3D geometry of the coronary artery will be developed using image segmentation procedure. The stent structure is smoothened within the coronary artery. Then, the geometry is meshed and CFD analysis is applied. The blood is assumed as a non-Newtonian fluid following a Carreau model of fluid viscosity. The inlet is applied with a velocity waveform, while the outlet is set as zero pressure. Lastly, the time averaged wall shear stress (TAWSS) is calculated. The region with TAWSS < 0.4 Pa is identified as a potential location for restenosis. From our simulations, the location in the middle of the stent shows TAWSS < 0.4 Pa, showing the potential of restenosis in the patient. |
| first_indexed | 2025-11-15T03:45:32Z |
| format | Conference or Workshop Item |
| id | ump-41971 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T03:45:32Z |
| publishDate | 2022 |
| publisher | IET |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-419712024-07-17T03:10:56Z http://umpir.ump.edu.my/id/eprint/41971/ Computational fluid dynamics of patient-specific coronary artery during stent treatment Nur Syuhada, Che Amdilah Lau, Yu Shi Liew, Yih Miin Wan Naimah, Wan Ab Naim Mohd Jamil, Mohamed Mokhtarudin QA75 Electronic computers. Computer science TJ Mechanical engineering and machinery Coronary artery disease is usually treated using stent treatment. However, restenosis is one of the major limitations of using stent. Local hemodynamics can be the main indicator of the occurrence of restenosis. In this project, a computational fluid dynamics (CFD) analysis is performed on a stented coronary artery patient with a 12-month follow-up post stent in order to determine the potential occurrence of restenosis in the patient. An OCT image of the coronary artery is taken and ethically approved from Universiti Malaya Medical Centre (UMMC). Firstly, a 3D geometry of the coronary artery will be developed using image segmentation procedure. The stent structure is smoothened within the coronary artery. Then, the geometry is meshed and CFD analysis is applied. The blood is assumed as a non-Newtonian fluid following a Carreau model of fluid viscosity. The inlet is applied with a velocity waveform, while the outlet is set as zero pressure. Lastly, the time averaged wall shear stress (TAWSS) is calculated. The region with TAWSS < 0.4 Pa is identified as a potential location for restenosis. From our simulations, the location in the middle of the stent shows TAWSS < 0.4 Pa, showing the potential of restenosis in the patient. IET 2022 Conference or Workshop Item PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/41971/1/Computational%20fluid%20dynamics%20of%20patient-specific%20coronary%20artery_ABST.pdf pdf en http://umpir.ump.edu.my/id/eprint/41971/2/Computational%20fluid%20dynamics%20of%20patient-specific%20coronary%20artery.pdf Nur Syuhada, Che Amdilah and Lau, Yu Shi and Liew, Yih Miin and Wan Naimah, Wan Ab Naim and Mohd Jamil, Mohamed Mokhtarudin (2022) Computational fluid dynamics of patient-specific coronary artery during stent treatment. In: IET Conference Proceedings. IET Conference Proceedings; 2022 Engineering Technology International Conference, ETIC 2022 , 07 - 08 September 2022 , Pahang, Virtual. 216 -220., 2022 (22). ISSN 2732-4494 ISBN 978-183953782-0 (Published) https://doi.org/10.1049/icp.2022.2608 |
| spellingShingle | QA75 Electronic computers. Computer science TJ Mechanical engineering and machinery Nur Syuhada, Che Amdilah Lau, Yu Shi Liew, Yih Miin Wan Naimah, Wan Ab Naim Mohd Jamil, Mohamed Mokhtarudin Computational fluid dynamics of patient-specific coronary artery during stent treatment |
| title | Computational fluid dynamics of patient-specific coronary artery during stent treatment |
| title_full | Computational fluid dynamics of patient-specific coronary artery during stent treatment |
| title_fullStr | Computational fluid dynamics of patient-specific coronary artery during stent treatment |
| title_full_unstemmed | Computational fluid dynamics of patient-specific coronary artery during stent treatment |
| title_short | Computational fluid dynamics of patient-specific coronary artery during stent treatment |
| title_sort | computational fluid dynamics of patient-specific coronary artery during stent treatment |
| topic | QA75 Electronic computers. Computer science TJ Mechanical engineering and machinery |
| url | http://umpir.ump.edu.my/id/eprint/41971/ http://umpir.ump.edu.my/id/eprint/41971/ http://umpir.ump.edu.my/id/eprint/41971/1/Computational%20fluid%20dynamics%20of%20patient-specific%20coronary%20artery_ABST.pdf http://umpir.ump.edu.my/id/eprint/41971/2/Computational%20fluid%20dynamics%20of%20patient-specific%20coronary%20artery.pdf |