Computational studies demonstrating dithymoquinone of Nigella sativa as a potential anti-dengue agent: Short review
Dengue is acute tropical infectious illness, which is spread by mosquitoes, has presented a significant threat to public health worldwide. Unfortunately, there are no drugs that have been clinically proven to be effective at treating or preventing dengue. The development of some drugs is significant...
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| Format: | Article |
| Language: | English |
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Elsevier
2024
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| Online Access: | http://umpir.ump.edu.my/id/eprint/41275/ http://umpir.ump.edu.my/id/eprint/41275/1/Computational%20studies%20demonstrating%20dithymoquinone%20of%20Nigella%20sativa.pdf |
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| author | Roney, Miah Mohd Fadhlizil Fasihi, Mohd Aluwi |
| author_facet | Roney, Miah Mohd Fadhlizil Fasihi, Mohd Aluwi |
| author_sort | Roney, Miah |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Dengue is acute tropical infectious illness, which is spread by mosquitoes, has presented a significant threat to public health worldwide. Unfortunately, there are no drugs that have been clinically proven to be effective at treating or preventing dengue. The development of some drugs is significantly hampered by our incomplete understanding of dengue pathogenesis. This short review provides a brief description of potential action against DENV of dithymoquinone to develop an anti-DENV inhibitor. In-vitro, in-vivo and clinical trials are required to establish the effectiveness and safety of dithymoquinone as an anti-dengue therapy, even though computational studies have demonstrated antiviral activity against DENV. |
| first_indexed | 2025-11-15T03:42:26Z |
| format | Article |
| id | ump-41275 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T03:42:26Z |
| publishDate | 2024 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-412752024-05-20T03:54:10Z http://umpir.ump.edu.my/id/eprint/41275/ Computational studies demonstrating dithymoquinone of Nigella sativa as a potential anti-dengue agent: Short review Roney, Miah Mohd Fadhlizil Fasihi, Mohd Aluwi Q Science (General) RA Public aspects of medicine TP Chemical technology Dengue is acute tropical infectious illness, which is spread by mosquitoes, has presented a significant threat to public health worldwide. Unfortunately, there are no drugs that have been clinically proven to be effective at treating or preventing dengue. The development of some drugs is significantly hampered by our incomplete understanding of dengue pathogenesis. This short review provides a brief description of potential action against DENV of dithymoquinone to develop an anti-DENV inhibitor. In-vitro, in-vivo and clinical trials are required to establish the effectiveness and safety of dithymoquinone as an anti-dengue therapy, even though computational studies have demonstrated antiviral activity against DENV. Elsevier 2024-02 Article PeerReviewed pdf en cc_by_4 http://umpir.ump.edu.my/id/eprint/41275/1/Computational%20studies%20demonstrating%20dithymoquinone%20of%20Nigella%20sativa.pdf Roney, Miah and Mohd Fadhlizil Fasihi, Mohd Aluwi (2024) Computational studies demonstrating dithymoquinone of Nigella sativa as a potential anti-dengue agent: Short review. Intelligent Pharmacy. pp. 1-4. ISSN 2949-866X. (In Press / Online First) (In Press / Online First) https://doi.org/10.1016/j.ipha.2024.02.006 https://doi.org/10.1016/j.ipha.2024.02.006 |
| spellingShingle | Q Science (General) RA Public aspects of medicine TP Chemical technology Roney, Miah Mohd Fadhlizil Fasihi, Mohd Aluwi Computational studies demonstrating dithymoquinone of Nigella sativa as a potential anti-dengue agent: Short review |
| title | Computational studies demonstrating dithymoquinone of Nigella sativa as a potential anti-dengue agent: Short review |
| title_full | Computational studies demonstrating dithymoquinone of Nigella sativa as a potential anti-dengue agent: Short review |
| title_fullStr | Computational studies demonstrating dithymoquinone of Nigella sativa as a potential anti-dengue agent: Short review |
| title_full_unstemmed | Computational studies demonstrating dithymoquinone of Nigella sativa as a potential anti-dengue agent: Short review |
| title_short | Computational studies demonstrating dithymoquinone of Nigella sativa as a potential anti-dengue agent: Short review |
| title_sort | computational studies demonstrating dithymoquinone of nigella sativa as a potential anti-dengue agent: short review |
| topic | Q Science (General) RA Public aspects of medicine TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/41275/ http://umpir.ump.edu.my/id/eprint/41275/ http://umpir.ump.edu.my/id/eprint/41275/ http://umpir.ump.edu.my/id/eprint/41275/1/Computational%20studies%20demonstrating%20dithymoquinone%20of%20Nigella%20sativa.pdf |