Optimization of Process Parameters of Immobilized Escherichia Coli for Cyclodextrin Production
The growing interest toward cylclodectrin (CD) application in industries is due to its unique structure that able to form inclusion complexes with substances. However, the problems arise during the CD synthesis using the commercial enzyme (cyclodextrin glucanotransferase) are low production rate and...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Semarak Ilmu Publishing
2023
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| Online Access: | http://umpir.ump.edu.my/id/eprint/40724/ http://umpir.ump.edu.my/id/eprint/40724/1/Optimization%20of%20Process%20Parameters%20of%20Immobilized%20Escherichia%20Coli%20for%20Cyclodextrin%20Production.pdf |
| _version_ | 1848826128557408256 |
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| author | Nur Nadia, Mohd Zakaria Rohaida, Che Man Siti Zubaidah, Sulaiman Siti Kholijah, Abdul Mudalip Nor Hasmaliana, Abdul Manas Navika Yamani, Laura |
| author_facet | Nur Nadia, Mohd Zakaria Rohaida, Che Man Siti Zubaidah, Sulaiman Siti Kholijah, Abdul Mudalip Nor Hasmaliana, Abdul Manas Navika Yamani, Laura |
| author_sort | Nur Nadia, Mohd Zakaria |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | The growing interest toward cylclodectrin (CD) application in industries is due to its unique structure that able to form inclusion complexes with substances. However, the problems arise during the CD synthesis using the commercial enzyme (cyclodextrin glucanotransferase) are low production rate and the process is expensive. Hence, cell immobilization system was used. The objective of this study is to optimize the process parameters using Response Surface Methodology to increase the CD production of the immobilized cell. High CD production was achieved after the optimization process. The reusability of immobilized cell also can be reuse up to six cycles using the optimized parameters. The findings propose that optimization process increased the CD production and made it more valuable for industrial application. |
| first_indexed | 2025-11-15T03:39:54Z |
| format | Article |
| id | ump-40724 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T03:39:54Z |
| publishDate | 2023 |
| publisher | Semarak Ilmu Publishing |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-407242024-03-21T05:45:49Z http://umpir.ump.edu.my/id/eprint/40724/ Optimization of Process Parameters of Immobilized Escherichia Coli for Cyclodextrin Production Nur Nadia, Mohd Zakaria Rohaida, Che Man Siti Zubaidah, Sulaiman Siti Kholijah, Abdul Mudalip Nor Hasmaliana, Abdul Manas Navika Yamani, Laura TP Chemical technology The growing interest toward cylclodectrin (CD) application in industries is due to its unique structure that able to form inclusion complexes with substances. However, the problems arise during the CD synthesis using the commercial enzyme (cyclodextrin glucanotransferase) are low production rate and the process is expensive. Hence, cell immobilization system was used. The objective of this study is to optimize the process parameters using Response Surface Methodology to increase the CD production of the immobilized cell. High CD production was achieved after the optimization process. The reusability of immobilized cell also can be reuse up to six cycles using the optimized parameters. The findings propose that optimization process increased the CD production and made it more valuable for industrial application. Semarak Ilmu Publishing 2023 Article PeerReviewed pdf en cc_by_nc_4 http://umpir.ump.edu.my/id/eprint/40724/1/Optimization%20of%20Process%20Parameters%20of%20Immobilized%20Escherichia%20Coli%20for%20Cyclodextrin%20Production.pdf Nur Nadia, Mohd Zakaria and Rohaida, Che Man and Siti Zubaidah, Sulaiman and Siti Kholijah, Abdul Mudalip and Nor Hasmaliana, Abdul Manas and Navika Yamani, Laura (2023) Optimization of Process Parameters of Immobilized Escherichia Coli for Cyclodextrin Production. Journal of Advanced Research in Applied Mechanics, 107 (1). pp. 1-10. ISSN 2289-7895. (Published) https://doi.org/10.37934/aram.107.1.110 10.37934/aram.107.1.110 |
| spellingShingle | TP Chemical technology Nur Nadia, Mohd Zakaria Rohaida, Che Man Siti Zubaidah, Sulaiman Siti Kholijah, Abdul Mudalip Nor Hasmaliana, Abdul Manas Navika Yamani, Laura Optimization of Process Parameters of Immobilized Escherichia Coli for Cyclodextrin Production |
| title | Optimization of Process Parameters of Immobilized Escherichia Coli for Cyclodextrin Production |
| title_full | Optimization of Process Parameters of Immobilized Escherichia Coli for Cyclodextrin Production |
| title_fullStr | Optimization of Process Parameters of Immobilized Escherichia Coli for Cyclodextrin Production |
| title_full_unstemmed | Optimization of Process Parameters of Immobilized Escherichia Coli for Cyclodextrin Production |
| title_short | Optimization of Process Parameters of Immobilized Escherichia Coli for Cyclodextrin Production |
| title_sort | optimization of process parameters of immobilized escherichia coli for cyclodextrin production |
| topic | TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/40724/ http://umpir.ump.edu.my/id/eprint/40724/ http://umpir.ump.edu.my/id/eprint/40724/ http://umpir.ump.edu.my/id/eprint/40724/1/Optimization%20of%20Process%20Parameters%20of%20Immobilized%20Escherichia%20Coli%20for%20Cyclodextrin%20Production.pdf |