Wound Healing Activity of Pyrazole-thiazole Derivatives of Curcumin Through the Docking, Pharmacokinetics, MD Simulation and MM/GBSA Approaches

Wound Healing Activity of Pyrazole-thiazole Derivatives of Curcumin Through the Docking, Pharmacokinetics, MD Simulation and MM/GBSA Approaches

Matrix metalloproteinase (MMP-2 and MMP-8) have been found to be promising targets for the discovery and development for of novel wound healing drugs candidate. However, there are currently no MMP-2 or MMP-8 inhibitors that are therapeutically helpful for treating wound healing. Therefore, the goal...

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Bibliographic Details
Main Authors: Forid, Md Shaekh, Roney, Miah, Uddin, Md. Nazim, Huq, A. K.M.Moyeenul, Mohd Hamzah, Mohd Nasir, Mohd Fadhlizil Fasihi, Mohd Aluwi, Muhammad Saupi, Azuri, Wan Maznah, Wan Ishak
Format: Article
Language:English
Published: International Scientific Organization 2024
Subjects:
T Technology (General)
TP Chemical technology
Online Access:http://umpir.ump.edu.my/id/eprint/40525/
http://umpir.ump.edu.my/id/eprint/40525/1/Wound%20Healing%20Activity%20of%20Pyrazole-thiazole%20Derivatives%20of%20Curcumin%20Through%20the%20Docking%2C%20Pharmacokinetics%2C%20MD%20Simulation%20and%20MM%20GBSA%20Approaches.pdf

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