Nose to brain delivery of selegiline loaded PLGA/lipid nanoparticles : Synthesis, characterisation and brain pharmacokinetics evaluation
Parkinson's disease (PD) is the second most common progressive neurodegenerative disease that promotes neuronal cell death. The primary treatment strategy for Parkinson's disease involves the therapy of an MAO-B inhibitor molecule, selegiline. The present research aims to fabricate selegil...
| Main Authors: | Raman, Subashini, Khan, Arshad Ali, Mahmood, Syed |
|---|---|
| Format: | Article |
| Language: | English English |
| Published: |
Editions de Sante
2022
|
| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/40195/ http://umpir.ump.edu.my/id/eprint/40195/1/Nose%20to%20brain%20delivery%20of%20selegiline%20loaded%20PLGA.pdf http://umpir.ump.edu.my/id/eprint/40195/2/Nose%20to%20brain%20delivery%20of%20selegiline%20loaded%20PLGA_lipid%20nanoparticles_Synthesis%2C%20characterisation%20and%20brain%20pharmacokinetics%20evaluation_ABS.pdf |
Similar Items
Polymeric Nanoparticles for Brain Drug Delivery - A Review
by: Subashini, Raman, et al.
Published: (2020)
by: Subashini, Raman, et al.
Published: (2020)
Development of lipid nanocapsules for antiangiogenic treatment of glioblastoma and evaluation of their potential for nose-to-brain drug delivery
by: Pourbaghi Masouleh, Milad
Published: (2019)
by: Pourbaghi Masouleh, Milad
Published: (2019)
Nose to brain drug delivery: a recent update
by: Chatterjee, Bappaditya
Published: (2017)
by: Chatterjee, Bappaditya
Published: (2017)
Evaluation of cell-penetrating peptides as tools to
improve nose-brain delivery of insulin
by: Brown, Alexander
Published: (2024)
by: Brown, Alexander
Published: (2024)
The development and application of biological models for evaluation of direct nose-to-brain drug delivery systems
by: Mistry, Alpesh
Published: (2009)
by: Mistry, Alpesh
Published: (2009)
A review on lipid-polymer hybrid nanoparticles and preparation with recent update
by: Subashini, Raman, et al.
Published: (2020)
by: Subashini, Raman, et al.
Published: (2020)
Development of nanoemulsion for efficient brain parental delivery of cefuroxime: designs,characterizations,and pharmacokinetics
by: Harun, Siti Norhawani, et al.
Published: (2018)
by: Harun, Siti Norhawani, et al.
Published: (2018)
Brain and artificial intelligence: from the viewpoint of
spontaneous and task-evoked brain dynamics
by: Sase, Takumi, et al.
Published: (2019)
by: Sase, Takumi, et al.
Published: (2019)
Nanoemulsion-based parenteral drug delivery system of carbamazepine: preparation, characterization, stability evaluation and blood-brain pharmacokinetics
by: Tan, Sim Ling, et al.
Published: (2015)
by: Tan, Sim Ling, et al.
Published: (2015)
Development of solid lipid nanoparticles for oral delivery of acyclovir and evaluation of its pharmacokinetics profile
by: Hassan, Haniza
Published: (2018)
by: Hassan, Haniza
Published: (2018)
Artificial nose for alcohol detection
by: Mohamad Koya, Muhamad Aslam, et al.
Published: (2010)
by: Mohamad Koya, Muhamad Aslam, et al.
Published: (2010)
Establishment of horse blood-brain barrier model for the study of drug delivery to the brain
by: Gupta, Gaurav
Published: (2025)
by: Gupta, Gaurav
Published: (2025)
Emotion recognition based on EEG: brain waves
by: Abdul Rahman, Abdul Wahab, et al.
Published: (2011)
by: Abdul Rahman, Abdul Wahab, et al.
Published: (2011)
De-Noising and Segmentation of Brain MR images by Spatial Information and K-Means Clustering
by: Javed, Arshad, et al.
Published: (2013)
by: Javed, Arshad, et al.
Published: (2013)
Segmentation of brain MR images with directional weighted optimized fuzzy C-means clustering
by: Arshad, Javed, et al.
Published: (2013)
by: Arshad, Javed, et al.
Published: (2013)
Performance analysis of different techniques for brain computer interfacing
by: Hasan, M. R., et al.
Published: (2013)
by: Hasan, M. R., et al.
Published: (2013)
Targeted delivery of BDNF-loaded poly (lactide-co-glycolide) nanoparticle to the brain: penetration through blood brain barrier and neuroprotective effect in stroke / Siti Norsyafika Kamarudin
by: Kamarudin, Siti Norsyafika
Published: (2019)
by: Kamarudin, Siti Norsyafika
Published: (2019)
Characterisation, in-vitro and in-vivo evaluation of valproic acid-loaded nanoemulsion for improved brain bioavailability
by: Tan, Suk Fei, et al.
Published: (2017)
by: Tan, Suk Fei, et al.
Published: (2017)
Evaluating Brain-in-Hand for adults with an acquired brain injury
by: Kettlewell, Jade
Published: (2019)
by: Kettlewell, Jade
Published: (2019)
Brain Changes in Iron Loading Disorders
by: Milward, E., et al.
Published: (2012)
by: Milward, E., et al.
Published: (2012)
Emotion recognition and brain mapping for sentiment analysis: a review
by: Hulliyah, Khodijah, et al.
Published: (2018)
by: Hulliyah, Khodijah, et al.
Published: (2018)
Understanding stress by analyzing the brain when solving mathematical task
by: Abdul Rahman, Abdul Wahab, et al.
Published: (2011)
by: Abdul Rahman, Abdul Wahab, et al.
Published: (2011)
Fundamental study on brain signal for BCI-FES System Development
by: A. Rahman, K. A., et al.
Published: (2012)
by: A. Rahman, K. A., et al.
Published: (2012)
Fundamental study on brain signal for bci-fes system development
by: A. Rahman, K. A., et al.
Published: (2012)
by: A. Rahman, K. A., et al.
Published: (2012)
Mouse mitochondrial lipid composition is defined by age in brain and muscle
by: Pollard, Amelia K., et al.
Published: (2017)
by: Pollard, Amelia K., et al.
Published: (2017)
CEST MRI for the characterisation of human brain tumours
by: Savvopoulos, Fotios
Published: (2020)
by: Savvopoulos, Fotios
Published: (2020)
Emotion detection from brain signals based on musical and visual stimuli
by: Othman, Marini, et al.
Published: (2011)
by: Othman, Marini, et al.
Published: (2011)
Understanding driver behavior according to brain signal and DASS 21 analysis
by: Abdul Rahman, Abdul Wahab, et al.
Published: (2011)
by: Abdul Rahman, Abdul Wahab, et al.
Published: (2011)
Understanding brain developmental disorder based on EEG in soft computing approach
Published: (2011)
Published: (2011)
Investigation on dynamic speech emotion from the perspective of brain associative memory.
by: Kamaruddin, Norhaslinda, et al.
Published: (2013)
by: Kamaruddin, Norhaslinda, et al.
Published: (2013)
Two dimensional affective state distribution of the brain under emotion stimuli
by: Yaacob, Hamwira Sakti, et al.
Published: (2012)
by: Yaacob, Hamwira Sakti, et al.
Published: (2012)
Tracking and analysis of EEG activation across brain lobes in an oddball task
by: Lim, Seng Hooi
Published: (2017)
by: Lim, Seng Hooi
Published: (2017)
Biomaterial-based local drug delivery to brain tumors
by: Rahman, Ruman
Published: (2014)
by: Rahman, Ruman
Published: (2014)
Brain tumor image segmentation using deep learning approach
by: Darshan, Suresh
Published: (2022)
by: Darshan, Suresh
Published: (2022)
Transdermal delivery of raloxifene HCl via ethosomal system: Formulation, advanced characterizations and pharmacokinetic evaluation
by: Mahmood, Syed, et al.
Published: (2018)
by: Mahmood, Syed, et al.
Published: (2018)
Effect of N. Sativa on Characteristics of gentamicin-loaded chitosan/PLGA microspheres
by: Mohamad Shukri, Najihah, et al.
Published: (2012)
by: Mohamad Shukri, Najihah, et al.
Published: (2012)
Targeted drug delivery to the brain via intranasal nanoemulsion: available proof of concept and existing challenges
by: Chatterjee, Bappaditya, et al.
Published: (2019)
by: Chatterjee, Bappaditya, et al.
Published: (2019)
Automated segmentation of brain MR images by combining Contourlet Transform and K-means Clustering techniques
by: Arshad, Javed, et al.
Published: (2013)
by: Arshad, Javed, et al.
Published: (2013)
Human brain plastination
by: Mohammed, Raed Hamzah, et al.
Published: (2017)
by: Mohammed, Raed Hamzah, et al.
Published: (2017)
PEGylation of PLGA and PCL nanoparticles enhanced the cytotoxicity of loaded 5-flurouracil
by: Ashour, Abdelkader Elbadawy Abbas, et al.
Published: (2017)
by: Ashour, Abdelkader Elbadawy Abbas, et al.
Published: (2017)
Similar Items
-
Polymeric Nanoparticles for Brain Drug Delivery - A Review
by: Subashini, Raman, et al.
Published: (2020) -
Development of lipid nanocapsules for antiangiogenic treatment of glioblastoma and evaluation of their potential for nose-to-brain drug delivery
by: Pourbaghi Masouleh, Milad
Published: (2019) -
Nose to brain drug delivery: a recent update
by: Chatterjee, Bappaditya
Published: (2017) -
Evaluation of cell-penetrating peptides as tools to
improve nose-brain delivery of insulin
by: Brown, Alexander
Published: (2024) -
The development and application of biological models for evaluation of direct nose-to-brain drug delivery systems
by: Mistry, Alpesh
Published: (2009)