Nose to brain delivery of selegiline loaded PLGA/lipid nanoparticles : Synthesis, characterisation and brain pharmacokinetics evaluation
Parkinson's disease (PD) is the second most common progressive neurodegenerative disease that promotes neuronal cell death. The primary treatment strategy for Parkinson's disease involves the therapy of an MAO-B inhibitor molecule, selegiline. The present research aims to fabricate selegil...
| Main Authors: | Raman, Subashini, Khan, Arshad Ali, Mahmood, Syed |
|---|---|
| Format: | Article |
| Language: | English English |
| Published: |
Editions de Sante
2022
|
| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/40195/ http://umpir.ump.edu.my/id/eprint/40195/1/Nose%20to%20brain%20delivery%20of%20selegiline%20loaded%20PLGA.pdf http://umpir.ump.edu.my/id/eprint/40195/2/Nose%20to%20brain%20delivery%20of%20selegiline%20loaded%20PLGA_lipid%20nanoparticles_Synthesis%2C%20characterisation%20and%20brain%20pharmacokinetics%20evaluation_ABS.pdf |
Similar Items
Development of lipid nanocapsules for antiangiogenic treatment of glioblastoma and evaluation of their potential for nose-to-brain drug delivery
by: Pourbaghi Masouleh, Milad
Published: (2019)
by: Pourbaghi Masouleh, Milad
Published: (2019)
Nose to brain drug delivery: a recent update
by: Chatterjee, Bappaditya
Published: (2017)
by: Chatterjee, Bappaditya
Published: (2017)
Polymeric Nanoparticles for Brain Drug Delivery - A Review
by: Subashini, Raman, et al.
Published: (2020)
by: Subashini, Raman, et al.
Published: (2020)
Evaluation of cell-penetrating peptides as tools to
improve nose-brain delivery of insulin
by: Brown, Alexander
Published: (2024)
by: Brown, Alexander
Published: (2024)
The development and application of biological models for evaluation of direct nose-to-brain drug delivery systems
by: Mistry, Alpesh
Published: (2009)
by: Mistry, Alpesh
Published: (2009)
Development of nanoemulsion for efficient brain parental delivery of cefuroxime: designs,characterizations,and pharmacokinetics
by: Harun, Siti Norhawani, et al.
Published: (2018)
by: Harun, Siti Norhawani, et al.
Published: (2018)
A review on lipid-polymer hybrid nanoparticles and preparation with recent update
by: Subashini, Raman, et al.
Published: (2020)
by: Subashini, Raman, et al.
Published: (2020)
Development of solid lipid nanoparticles for oral delivery of acyclovir and evaluation of its pharmacokinetics profile
by: Hassan, Haniza
Published: (2018)
by: Hassan, Haniza
Published: (2018)
Nanoemulsion-based parenteral drug delivery system of carbamazepine: preparation, characterization, stability evaluation and blood-brain pharmacokinetics
by: Tan, Sim Ling, et al.
Published: (2015)
by: Tan, Sim Ling, et al.
Published: (2015)
Targeted delivery of BDNF-loaded poly (lactide-co-glycolide) nanoparticle to the brain: penetration through blood brain barrier and neuroprotective effect in stroke / Siti Norsyafika Kamarudin
by: Kamarudin, Siti Norsyafika
Published: (2019)
by: Kamarudin, Siti Norsyafika
Published: (2019)
PEGylation of PLGA and PCL nanoparticles enhanced the cytotoxicity of loaded 5-flurouracil
by: Ashour, Abdelkader Elbadawy Abbas, et al.
Published: (2017)
by: Ashour, Abdelkader Elbadawy Abbas, et al.
Published: (2017)
Establishment of horse blood-brain barrier model for the study of drug delivery to the brain
by: Gupta, Gaurav
Published: (2025)
by: Gupta, Gaurav
Published: (2025)
Intranasal Delivery Of Andrographolide Nanoparticles For Improvement Of Cognitive Function: In Vitro And In Vivo Evaluation
by: Raman, Subashini
Published: (2024)
by: Raman, Subashini
Published: (2024)
Fabrication of non-viral gene delivery system of N.sativa/chitosan/PLGA nanoparticles
by: Mansor, Nur 'Izzati, et al.
Published: (2013)
by: Mansor, Nur 'Izzati, et al.
Published: (2013)
Physical pegylation enhances the cytotoxicity of 5-fluorouracil-loaded PLGA And PCL nanoparticles.
by: Ashour, Abdelkader Elbadawy Abbas, et al.
Published: (2019)
by: Ashour, Abdelkader Elbadawy Abbas, et al.
Published: (2019)
Evaluation of a nanoparticle drug delivery vehicle in medulloblastoma and organotypic brain cell cultures
by: Meng, Weina
Published: (2006)
by: Meng, Weina
Published: (2006)
Characterisation, in-vitro and in-vivo evaluation of valproic acid-loaded nanoemulsion for improved brain bioavailability
by: Tan, Suk Fei, et al.
Published: (2017)
by: Tan, Suk Fei, et al.
Published: (2017)
Brain Changes in Iron Loading Disorders
by: Milward, E., et al.
Published: (2012)
by: Milward, E., et al.
Published: (2012)
Tumor suppressor P73-loaded PLGA/chitosan nanoparticles: a novel non-viral gene delivery system for oral squamous cell carcinoma therapy
by: Ichwan, Solachuddin J. A., et al.
Published: (2019)
by: Ichwan, Solachuddin J. A., et al.
Published: (2019)
PLGA-Chitosan nanoparticle-mediated gene delivery for oral cancer treatment: A brief review
by: Bakar, Latifah Munirah, et al.
Published: (2017)
by: Bakar, Latifah Munirah, et al.
Published: (2017)
An ion pairing approach to increase the loading of hydrophilic and lipophilic drugs into PEGylated PLGA nanoparticles
by: Dalwadi, G., et al.
Published: (2009)
by: Dalwadi, G., et al.
Published: (2009)
Assessment of drug-loaded nanoparticles in a 3D in vitro brain tumour model
by: Ivanov, Delyan Pavlov
Published: (2015)
by: Ivanov, Delyan Pavlov
Published: (2015)
Mouse mitochondrial lipid composition is defined by age in brain and muscle
by: Pollard, Amelia K., et al.
Published: (2017)
by: Pollard, Amelia K., et al.
Published: (2017)
CEST MRI for the characterisation of human brain tumours
by: Savvopoulos, Fotios
Published: (2020)
by: Savvopoulos, Fotios
Published: (2020)
Effect of formulation factors on incorporation of the hydrophilic peptide dalargin into PLGA and mPEG-PLGA nanoparticles
by: Chen, Yan, et al.
Published: (2008)
by: Chen, Yan, et al.
Published: (2008)
Biomaterial-based local drug delivery to brain tumors
by: Rahman, Ruman
Published: (2014)
by: Rahman, Ruman
Published: (2014)
The effect of ageing on the blood-brain barrier: The potential of nanoparticle drug delivery systems to target cerebrovascular changes
by: Bates, Jessica
Published: (2025)
by: Bates, Jessica
Published: (2025)
Effect of N. Sativa on Characteristics of gentamicin-loaded chitosan/PLGA microspheres
by: Mohamad Shukri, Najihah, et al.
Published: (2012)
by: Mohamad Shukri, Najihah, et al.
Published: (2012)
Synthesis And Characterisation Of PEG-PLGA Nanoparticles For Geraniin Isolated From Phyllanthus watsonii (Dukung Anak) Extract
by: Jairaman, Sreegayathri
Published: (2018)
by: Jairaman, Sreegayathri
Published: (2018)
Human brain plastination
by: Mohammed, Raed Hamzah, et al.
Published: (2017)
by: Mohammed, Raed Hamzah, et al.
Published: (2017)
Brain and artificial intelligence: from the viewpoint of
spontaneous and task-evoked brain dynamics
by: Sase, Takumi, et al.
Published: (2019)
by: Sase, Takumi, et al.
Published: (2019)
PLGA microcapsules with novel dimpled surfaces for pulmonary delivery of DNA
by: Mohamed, Farahidah, et al.
Published: (2006)
by: Mohamed, Farahidah, et al.
Published: (2006)
Modern methods for delivery of drugs across the blood-brain barrier
by: Chen, Yan, et al.
Published: (2012)
by: Chen, Yan, et al.
Published: (2012)
Apoferritin delivery of imidazotetrazine agents for targeted brain tumour therapy
by: Bouzinab, Kaouthar
Published: (2021)
by: Bouzinab, Kaouthar
Published: (2021)
Development of alpha mangostin-PLGA nanoparticles as an anticancer agent
by: Aimen, Abdo, et al.
Published: (2011)
by: Aimen, Abdo, et al.
Published: (2011)
The study of the effects of different surfactants, concentration of PVA and molecular weight of PLGA on the development of Gentamicin-loaded PLGA microspheres
by: Harun Ismail, Ahmad Fahmi, et al.
Published: (2010)
by: Harun Ismail, Ahmad Fahmi, et al.
Published: (2010)
Brain Basics Module for MOOC and Brain awareness for secondary school in Sarawak, 2017-2018
by: Norsiah, Fauzan, et al.
Published: (2017)
by: Norsiah, Fauzan, et al.
Published: (2017)
Brains vs industrial brawn
by: Abd Razak, Dzulkifli
Published: (2005)
by: Abd Razak, Dzulkifli
Published: (2005)
Potential Non-invasive Tracheobronchial targeted delivery of DNA by PLGA microspheres
by: Mohamed, Farahidah, et al.
Published: (2010)
by: Mohamed, Farahidah, et al.
Published: (2010)
Development of a glucose sensitive insulin delivery PLGA microparticle system
by: Dino, Mohamad Hadid Amshah
Published: (2018)
by: Dino, Mohamad Hadid Amshah
Published: (2018)
Similar Items
-
Development of lipid nanocapsules for antiangiogenic treatment of glioblastoma and evaluation of their potential for nose-to-brain drug delivery
by: Pourbaghi Masouleh, Milad
Published: (2019) -
Nose to brain drug delivery: a recent update
by: Chatterjee, Bappaditya
Published: (2017) -
Polymeric Nanoparticles for Brain Drug Delivery - A Review
by: Subashini, Raman, et al.
Published: (2020) -
Evaluation of cell-penetrating peptides as tools to
improve nose-brain delivery of insulin
by: Brown, Alexander
Published: (2024) -
The development and application of biological models for evaluation of direct nose-to-brain drug delivery systems
by: Mistry, Alpesh
Published: (2009)