Fouling characteristics and cleaning approach of ultrafiltration membrane during xylose reductase separation
Many operating parameters of ultrafiltration (UF) are playing a crucial role when using a polyethersulfone membrane to separate xylose reductase (XR) enzyme from reaction mixtures during xylitol synthesis. The present study focuses on the separation of XR enzyme using a cross-flow ultrafiltration (U...
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| Format: | Article |
| Language: | English English |
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Springer Science and Business Media Deutschland GmbH
2022
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| Online Access: | http://umpir.ump.edu.my/id/eprint/40119/ http://umpir.ump.edu.my/id/eprint/40119/1/Fouling%20characteristics%20and%20cleaning%20approach%20of%20ultrafiltration.pdf http://umpir.ump.edu.my/id/eprint/40119/2/Fouling%20characteristics%20and%20cleaning%20approach%20of%20ultrafiltration_ABS.pdf |
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| author | Krishnan, Santhana Mohd, Nasrullah Kamyab, Hesam Noor, Suzana Mimi Sakinah, Abdul Munaim Zularisam, Abdul Wahid Ali, Ismat Hassan Salehi, Reza Chaiprapat, Sumate S. |
| author_facet | Krishnan, Santhana Mohd, Nasrullah Kamyab, Hesam Noor, Suzana Mimi Sakinah, Abdul Munaim Zularisam, Abdul Wahid Ali, Ismat Hassan Salehi, Reza Chaiprapat, Sumate S. |
| author_sort | Krishnan, Santhana |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Many operating parameters of ultrafiltration (UF) are playing a crucial role when using a polyethersulfone membrane to separate xylose reductase (XR) enzyme from reaction mixtures during xylitol synthesis. The present study focuses on the separation of XR enzyme using a cross-flow ultrafiltration (UF) membrane. The filtration process was analyzed using the three effective variables such as filtration time, cross-flow velocity (CFV), and the transmembrane pressure (TMP), which were ranging from 0 to 100 min, 0.52 to 1.2 cm/s and 1–1.6 bar, respectively. Then, using the resistance in series model, the hydraulic resistance for alkali chemical cleaning during XR separation was estimated. During separation, increased TMP showed a positive-flux effect as a driving force, however, fouling and polarized layer were more prominent under higher TMP. Increased CFV, on the other hand, was found more efficient in fouling control. In terms of the membrane cleaning techniques, an alkaline solution containing 0.1 M sodium hydroxide was shown to be the most effective substance in removing foulants from the membrane surface in this investigation. Cleaning with an alkaline solution resulted in a maximum flux recovery of 93% for xylose reductase separation. This work may serve as a useful guide to better understand the optimization parameters during XR separation and alleviating UF membrane fouling induced during XR separation. |
| first_indexed | 2025-11-15T03:37:12Z |
| format | Article |
| id | ump-40119 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T03:37:12Z |
| publishDate | 2022 |
| publisher | Springer Science and Business Media Deutschland GmbH |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-401192024-01-19T09:30:22Z http://umpir.ump.edu.my/id/eprint/40119/ Fouling characteristics and cleaning approach of ultrafiltration membrane during xylose reductase separation Krishnan, Santhana Mohd, Nasrullah Kamyab, Hesam Noor, Suzana Mimi Sakinah, Abdul Munaim Zularisam, Abdul Wahid Ali, Ismat Hassan Salehi, Reza Chaiprapat, Sumate S. QD Chemistry T Technology (General) TA Engineering (General). Civil engineering (General) TP Chemical technology Many operating parameters of ultrafiltration (UF) are playing a crucial role when using a polyethersulfone membrane to separate xylose reductase (XR) enzyme from reaction mixtures during xylitol synthesis. The present study focuses on the separation of XR enzyme using a cross-flow ultrafiltration (UF) membrane. The filtration process was analyzed using the three effective variables such as filtration time, cross-flow velocity (CFV), and the transmembrane pressure (TMP), which were ranging from 0 to 100 min, 0.52 to 1.2 cm/s and 1–1.6 bar, respectively. Then, using the resistance in series model, the hydraulic resistance for alkali chemical cleaning during XR separation was estimated. During separation, increased TMP showed a positive-flux effect as a driving force, however, fouling and polarized layer were more prominent under higher TMP. Increased CFV, on the other hand, was found more efficient in fouling control. In terms of the membrane cleaning techniques, an alkaline solution containing 0.1 M sodium hydroxide was shown to be the most effective substance in removing foulants from the membrane surface in this investigation. Cleaning with an alkaline solution resulted in a maximum flux recovery of 93% for xylose reductase separation. This work may serve as a useful guide to better understand the optimization parameters during XR separation and alleviating UF membrane fouling induced during XR separation. Springer Science and Business Media Deutschland GmbH 2022-07 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/40119/1/Fouling%20characteristics%20and%20cleaning%20approach%20of%20ultrafiltration.pdf pdf en http://umpir.ump.edu.my/id/eprint/40119/2/Fouling%20characteristics%20and%20cleaning%20approach%20of%20ultrafiltration_ABS.pdf Krishnan, Santhana and Mohd, Nasrullah and Kamyab, Hesam and Noor, Suzana and Mimi Sakinah, Abdul Munaim and Zularisam, Abdul Wahid and Ali, Ismat Hassan and Salehi, Reza and Chaiprapat, Sumate S. (2022) Fouling characteristics and cleaning approach of ultrafiltration membrane during xylose reductase separation. Bioprocess and Biosystems Engineering, 45 (7). pp. 1125-1136. ISSN 1615-7591. (Published) https://doi.org/10.1007/s00449-022-02726-8 https://doi.org/10.1007/s00449-022-02726-8 |
| spellingShingle | QD Chemistry T Technology (General) TA Engineering (General). Civil engineering (General) TP Chemical technology Krishnan, Santhana Mohd, Nasrullah Kamyab, Hesam Noor, Suzana Mimi Sakinah, Abdul Munaim Zularisam, Abdul Wahid Ali, Ismat Hassan Salehi, Reza Chaiprapat, Sumate S. Fouling characteristics and cleaning approach of ultrafiltration membrane during xylose reductase separation |
| title | Fouling characteristics and cleaning approach of ultrafiltration membrane during xylose reductase separation |
| title_full | Fouling characteristics and cleaning approach of ultrafiltration membrane during xylose reductase separation |
| title_fullStr | Fouling characteristics and cleaning approach of ultrafiltration membrane during xylose reductase separation |
| title_full_unstemmed | Fouling characteristics and cleaning approach of ultrafiltration membrane during xylose reductase separation |
| title_short | Fouling characteristics and cleaning approach of ultrafiltration membrane during xylose reductase separation |
| title_sort | fouling characteristics and cleaning approach of ultrafiltration membrane during xylose reductase separation |
| topic | QD Chemistry T Technology (General) TA Engineering (General). Civil engineering (General) TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/40119/ http://umpir.ump.edu.my/id/eprint/40119/ http://umpir.ump.edu.my/id/eprint/40119/ http://umpir.ump.edu.my/id/eprint/40119/1/Fouling%20characteristics%20and%20cleaning%20approach%20of%20ultrafiltration.pdf http://umpir.ump.edu.my/id/eprint/40119/2/Fouling%20characteristics%20and%20cleaning%20approach%20of%20ultrafiltration_ABS.pdf |