Peripheral Antinociception of a Chalcone, Flavokawin B and Possible Involvement of the Nitric Oxide/Cyclic Guanosine Monophosphate/Potassium Channels Pathway
Previous studies have shown that systemic administration of 6'-hydroxy-2',4'-dimethoxychalcone (flavokawin B, FKB) exerts significant peripheral and central antinociceptive effects in laboratory animals. However, the mechanisms underlying these peripheral and central antinociceptive e...
| Main Authors: | Akhtar, Muhammad Nadeem, Mohd Nasier, Kamaldin, Azam Shah, Mohamad, Lajis, Nordin, Perimal, Enoch Kumar, Akira, Ahmad, Lee, Ming-Tatt, Israf, Daud Ahmad, Mohd Roslan, Sulaiman |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI - Open Access Publishing
2013
|
| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/3881/ http://umpir.ump.edu.my/id/eprint/3881/1/fist-2013-Nadeem-peripheral_antinociception_of.pdf |
Similar Items
Peripheral antinociception of a chalcone, flavokawin B and possible involvement of the nitric oxide/cyclic guanosine monophosphate/potassium channels pathway
by: Kamaldin, Mohd Nasier, et al.
Published: (2013)
by: Kamaldin, Mohd Nasier, et al.
Published: (2013)
Possible participation of nitric oxide/cyclic guanosine monophosphate/protein kinase C/ATP-sensitive K + channels pathway in the systemic antinociception of flavokawin B.
by: Tengku Mohamad, Tengku Azam Shah, et al.
Published: (2011)
by: Tengku Mohamad, Tengku Azam Shah, et al.
Published: (2011)
Possible participation of ionotropic glutamate receptors and L-arginine-nitric oxide-cyclic guanosine monophosphate-ATP-sensitive K+ channel pathway in the antinociceptive activity of cardamonin in acute pain animal models
by: Chung, Pui Ping, et al.
Published: (2020)
by: Chung, Pui Ping, et al.
Published: (2020)
Possible participation of ionotropic glutamate receptors and l-arginine-nitric oxide-cyclic guanosine monophosphate-ATP-Sensitive K+ channel pathway in the antinociceptive activity of cardamonin in acute pain animal models
by: Chung, Pui Ping, et al.
Published: (2020)
by: Chung, Pui Ping, et al.
Published: (2020)
Antinociceptive activity of a synthetic chalcone, flavokawin B on chemical and thermal models of nociception in mice
by: Tengku Mohamad, Tengku Azam Shah, et al.
Published: (2010)
by: Tengku Mohamad, Tengku Azam Shah, et al.
Published: (2010)
Possible participation of protein kinase C and cyclic guanosine monophosphate pathway in antinociception of ethanol extract of Ficus deltoidea var angustifolia leaves in mice
by: Hussain, Mohd Khairi, et al.
Published: (2014)
by: Hussain, Mohd Khairi, et al.
Published: (2014)
Zerumbone-induced antinociception: involvement of the L-arginine-nitric oxide-cGMP -PKC-K+ ATP channel pathways.
by: Perimal, Enoch Kumar, et al.
Published: (2011)
by: Perimal, Enoch Kumar, et al.
Published: (2011)
Antinociceptive Effect of 3-(2,3-Dimethoxyphenyl)-1-(5-methylfuran-2-yl)prop-2-en-1-one in Mice Models of Induced Nociception
by: Nur Izzati, Ismail, et al.
Published: (2016)
by: Nur Izzati, Ismail, et al.
Published: (2016)
Participation of Large Ca2+ Activated Potassium Channel in Antinociceptive Activity of Chalcone Derivative (3-(2, 5-dimethoxyphenyl)-1-(5-methylfuran-2-yl) prop-2-en-1-one) DMPF-1 Action in Mice Model
by: Akhtar, Muhammad Nadeem, et al.
Published: (2013)
by: Akhtar, Muhammad Nadeem, et al.
Published: (2013)
Antinociceptive effect of the essential oil of Zingiber zerumbet in mice : possible mechanisms
by: Khalid, Mohamed Hanief, et al.
Published: (2011)
by: Khalid, Mohamed Hanief, et al.
Published: (2011)
Preliminary analysis of the antinociceptive activity of zerumbone
by: Sulaiman, Mohd Roslan, et al.
Published: (2009)
by: Sulaiman, Mohd Roslan, et al.
Published: (2009)
Antinociceptive effect of 3-(2,3-dimethoxyphenyl)-1-(5-methylfuran-2-yl)prop-2-en-1-one in mice models of induced nociception
by: Ismail, Nur Izzati, et al.
Published: (2016)
by: Ismail, Nur Izzati, et al.
Published: (2016)
Antinociceptive Effects of Cardamonin in Mice: Possible Involvement of TRPV1, Glutamate, and Opioid Receptors
by: Chung, Pui Ping, et al.
Published: (2018)
by: Chung, Pui Ping, et al.
Published: (2018)
Antinociceptive effects of cardamonin in mice: Possible involvement of TRPV1, glutamate and opioid receptors
by: Chung, Pui Ping, et al.
Published: (2018)
by: Chung, Pui Ping, et al.
Published: (2018)
Antinociceptive and Anti-Inflammatory Activities of Zerumbone from Zingiber Zerumbet (l.) Roscoe ex sm., and its Possible Mechanisms of Action
by: Perimal, Enoch Kumar
Published: (2012)
by: Perimal, Enoch Kumar
Published: (2012)
Influence of fresh and thermoxidized carotino oil on Cyclic Guanosine Monophosphate (cGMP) in erythrocytes from Sprague dawley rats / Mohd Fakharul Zaman Raja Yahya and Athifah Najwani Shahidan
by: Raja Yahya, Mohd Fakharul Zaman, et al.
Published: (2012)
by: Raja Yahya, Mohd Fakharul Zaman, et al.
Published: (2012)
Antinociceptive activity of a synthetic curcuminoid analogue, 2,6-bis-(4-hydroxy-3-methoxybenzylidene)cyclohexanone, on nociception-induced models in mice.
by: Lee, Ming Tatt, et al.
Published: (2012)
by: Lee, Ming Tatt, et al.
Published: (2012)
Rethinking phosphatidylinositol 3-monophosphate
by: Falasca, Marco, et al.
Published: (2009)
by: Falasca, Marco, et al.
Published: (2009)
Evaluation of antinociceptive profile of chalcone derivative (3-(2,5-dimethoxyphenyl)-1-(5-
methylfuran-2-yl) prop-2-en-1-one (DMPF-1) in vivo
by: Noor Azlina, Abu Bakar, et al.
Published: (2020)
by: Noor Azlina, Abu Bakar, et al.
Published: (2020)
Antinociceptive activity of methanolic extract of Acmella uliginosa (Sw.) Cass.
by: Ong, Hui Ming, et al.
Published: (2011)
by: Ong, Hui Ming, et al.
Published: (2011)
Involvement of opioid receptors in Boesenbergia pandurata's esssential oil (BPEO)-induced antinociceptive activity in animal model of nociception
by: Makhtar, Nor 'Adilah, et al.
Published: (2012)
by: Makhtar, Nor 'Adilah, et al.
Published: (2012)
Anti-hyperalgesic Effect of a Benzilidine-cyclohexanone Analogue on a Mouse Model of Chronic Constriction Injury-induced Neuropathic Pain: Participation of the κ-opioid Receptor and KATP
by: Akhtar, Muhammad Nadeem, et al.
Published: (2013)
by: Akhtar, Muhammad Nadeem, et al.
Published: (2013)
Antinociceptive activities of a novel diarylpentanoid analogue, 2-benzoyl-6-(3-bromo-4-hydroxybenzylidene)cyclohexen-1-ol, and its possible mechanisms of action in mice
by: Ong, Hui Ming, et al.
Published: (2021)
by: Ong, Hui Ming, et al.
Published: (2021)
Antinociceptive activity of Melicope ptefolia ethanolic extract in experimental animals
by: Sulaiman, Mohd Roslan, et al.
Published: (2010)
by: Sulaiman, Mohd Roslan, et al.
Published: (2010)
Antinociceptive activity of Melicope ptelefolia ethanolic extract in experimental animals.
by: Sulaiman, Mohd Roslan, et al.
Published: (2010)
by: Sulaiman, Mohd Roslan, et al.
Published: (2010)
Inhibition of nitric oxide and prostaglandin E2 production by pyrrolylated-chalcones : synthesis, biological activity, crystal structure analysis, and molecular docking studies
by: Siti Munirah, Mohd Faudzi, et al.
Published: (2020)
by: Siti Munirah, Mohd Faudzi, et al.
Published: (2020)
Inhibition of nitric oxide and prostaglandin E2 production by pyrrolylated-chalcones: synthesis, biological activity, crystal structure analysis, and molecular docking studies
by: Mohd Faudzi, Siti Munirah, et al.
Published: (2020)
by: Mohd Faudzi, Siti Munirah, et al.
Published: (2020)
Anti-hyperalgesic effect of a benzilidine-cyclohexanone analogue on a mouse model of chronic constriction injury-induced neuropathic pain: participation of the κ-opioid receptor and KATP
by: Lee, Ming Tatt, et al.
Published: (2013)
by: Lee, Ming Tatt, et al.
Published: (2013)
Inhibition of nitric oxide and prostaglandin E2 production by pyrrolylated-chalcones: synthesis, biological activity, crystal structure analysis, and molecular docking studies
by: Mohd Faudzi, Siti Munirah, et al.
Published: (2020)
by: Mohd Faudzi, Siti Munirah, et al.
Published: (2020)
Antinociceptive activity of the essential oil of Zingiber zerumbet.
by: Sulaiman, Mohd Roslan, et al.
Published: (2010)
by: Sulaiman, Mohd Roslan, et al.
Published: (2010)
The Flavokawains: Uprising Medicinal Chalcones
by: Akhtar, Muhammad Nadeem, et al.
Published: (2013)
by: Akhtar, Muhammad Nadeem, et al.
Published: (2013)
The flavokawains: uprising medicinal chalcones
by: Abu, Nadiah, et al.
Published: (2013)
by: Abu, Nadiah, et al.
Published: (2013)
The involvement of L-arginine-nitric ox-ide-cGMP-ATP-sensitive K+ channel pathway in antinocicep-tion of BBHC, a novel diarylpentanoid analogue, in mice model
by: Hui, Ming Ong, et al.
Published: (2021)
by: Hui, Ming Ong, et al.
Published: (2021)
Methanolic extract of Clinacanthus nutans exerts antinociceptive activity via the opioid/nitric oxide-mediated, but cGMP-independent, pathways
by: Abdul Rahim, Mohammad Hafiz, et al.
Published: (2016)
by: Abdul Rahim, Mohammad Hafiz, et al.
Published: (2016)
Cardamonin (2′,4′-dihydroxy-6′-methoxychalcone) Isolated from Boesenbergia Rotunda (L.) Mansf. Inhibits CFA-induced Rheumatoid Arthritis in Rats
by: Fui-Ling, Voon, et al.
Published: (2017)
by: Fui-Ling, Voon, et al.
Published: (2017)
Activity of cardamonin on chemical model of nociception in mice
by: Chung, Pui Ping, et al.
Published: (2014)
by: Chung, Pui Ping, et al.
Published: (2014)
Elucidation of basic mechanisms of flavokawin B inhibitory effects on the growth of selected cancer and transformed normal cell lines
by: Umar, Nasir Tsafe
Published: (2008)
by: Umar, Nasir Tsafe
Published: (2008)
The effect of adenosine monophosphate deaminase overexpression on the accumulation of umami-related metabolites in tomatoes
by: Chew, Bee Lynn, et al.
Published: (2016)
by: Chew, Bee Lynn, et al.
Published: (2016)
Preliminary study on antinociceptove effect of aqueous extract of Boesenbergia pandurata in formalin-induced nociception test in mice
by: Ee, Ai Chin, et al.
Published: (2014)
by: Ee, Ai Chin, et al.
Published: (2014)
Zerumbone alleviates neuropathic pain through the involvement of L-arginine-nitric oxide-cGMP-K+ ATP channel pathways in chronic constriction injury in mice model
by: Zulazmi, Nurul Atiqah, et al.
Published: (2017)
by: Zulazmi, Nurul Atiqah, et al.
Published: (2017)
Similar Items
-
Peripheral antinociception of a chalcone, flavokawin B and possible involvement of the nitric oxide/cyclic guanosine monophosphate/potassium channels pathway
by: Kamaldin, Mohd Nasier, et al.
Published: (2013) -
Possible participation of nitric oxide/cyclic guanosine monophosphate/protein kinase C/ATP-sensitive K + channels pathway in the systemic antinociception of flavokawin B.
by: Tengku Mohamad, Tengku Azam Shah, et al.
Published: (2011) -
Possible participation of ionotropic glutamate receptors and L-arginine-nitric oxide-cyclic guanosine monophosphate-ATP-sensitive K+ channel pathway in the antinociceptive activity of cardamonin in acute pain animal models
by: Chung, Pui Ping, et al.
Published: (2020) -
Possible participation of ionotropic glutamate receptors and l-arginine-nitric oxide-cyclic guanosine monophosphate-ATP-Sensitive K+ channel pathway in the antinociceptive activity of cardamonin in acute pain animal models
by: Chung, Pui Ping, et al.
Published: (2020) -
Antinociceptive activity of a synthetic chalcone, flavokawin B on chemical and thermal models of nociception in mice
by: Tengku Mohamad, Tengku Azam Shah, et al.
Published: (2010)