Delivery of bioencapsulated proteins
Proteins and peptides have been used in pharmaceutical, nutraceutical, and food applications for their therapeutic and nutritional properties. However, administration of these molecules to the human body is challenging due to their low stability, low bioavailability, high biodegradability, immunogen...
| Main Authors: | , , , , , , , |
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| Format: | Book Chapter |
| Language: | English English |
| Published: |
Elsevier
2023
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| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/37685/ http://umpir.ump.edu.my/id/eprint/37685/1/Delivery%20of%20bioencapsulated%20proteins.pdf http://umpir.ump.edu.my/id/eprint/37685/7/11.Delivery%20of%20bioencapsulated%20proteins.pdf |
| _version_ | 1848825319129088000 |
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| author | Nor Hasmaliana, Abdul Manas Dayang Norulfairuz, Abang Zaidel Nur Izyan, Wan Azelee Siti Fatimah Zaharah, Mohd Fuzi Aizi Nor Mazila, Ramli Shalyda, Md Shaarani Rosli, Md. Illias Norsuhada, Abdul Karim |
| author_facet | Nor Hasmaliana, Abdul Manas Dayang Norulfairuz, Abang Zaidel Nur Izyan, Wan Azelee Siti Fatimah Zaharah, Mohd Fuzi Aizi Nor Mazila, Ramli Shalyda, Md Shaarani Rosli, Md. Illias Norsuhada, Abdul Karim |
| author_sort | Nor Hasmaliana, Abdul Manas |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Proteins and peptides have been used in pharmaceutical, nutraceutical, and food applications for their therapeutic and nutritional properties. However, administration of these molecules to the human body is challenging due to their low stability, low bioavailability, high biodegradability, immunogenicity, and inefficient permeability. These molecules require a tailored delivery system to ensure bioavailability and efficient maintenance to target location. Nanotechnology has emerged as an ideal platform in drug delivery as it provides a versatile system with excellent biocompatibility. This chapter discusses various nanomaterials that have been explored, particularly organic, inorganic, protein, and hybrid nanomaterials which are biocompatible for administration to human body. Challenges for the development of protein in nanomaterials are outlined and strategies for the nanoencapsulation in these nano-vehicles are discussed that aim for preservation of bioactivity, high protein loading, structural stability, permeability, and control release besides being easy for synthesis and cost-effective. |
| first_indexed | 2025-11-15T03:27:02Z |
| format | Book Chapter |
| id | ump-37685 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T03:27:02Z |
| publishDate | 2023 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-376852023-08-16T23:59:01Z http://umpir.ump.edu.my/id/eprint/37685/ Delivery of bioencapsulated proteins Nor Hasmaliana, Abdul Manas Dayang Norulfairuz, Abang Zaidel Nur Izyan, Wan Azelee Siti Fatimah Zaharah, Mohd Fuzi Aizi Nor Mazila, Ramli Shalyda, Md Shaarani Rosli, Md. Illias Norsuhada, Abdul Karim QD Chemistry QP Physiology RS Pharmacy and materia medica T Technology (General) Proteins and peptides have been used in pharmaceutical, nutraceutical, and food applications for their therapeutic and nutritional properties. However, administration of these molecules to the human body is challenging due to their low stability, low bioavailability, high biodegradability, immunogenicity, and inefficient permeability. These molecules require a tailored delivery system to ensure bioavailability and efficient maintenance to target location. Nanotechnology has emerged as an ideal platform in drug delivery as it provides a versatile system with excellent biocompatibility. This chapter discusses various nanomaterials that have been explored, particularly organic, inorganic, protein, and hybrid nanomaterials which are biocompatible for administration to human body. Challenges for the development of protein in nanomaterials are outlined and strategies for the nanoencapsulation in these nano-vehicles are discussed that aim for preservation of bioactivity, high protein loading, structural stability, permeability, and control release besides being easy for synthesis and cost-effective. Elsevier 2023 Book Chapter PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/37685/1/Delivery%20of%20bioencapsulated%20proteins.pdf pdf en http://umpir.ump.edu.my/id/eprint/37685/7/11.Delivery%20of%20bioencapsulated%20proteins.pdf Nor Hasmaliana, Abdul Manas and Dayang Norulfairuz, Abang Zaidel and Nur Izyan, Wan Azelee and Siti Fatimah Zaharah, Mohd Fuzi and Aizi Nor Mazila, Ramli and Shalyda, Md Shaarani and Rosli, Md. Illias and Norsuhada, Abdul Karim (2023) Delivery of bioencapsulated proteins. In: Smart Nanomaterials for Bioencapsulation. Elsevier, pp. 63-75. ISBN 9780323912297 (Unpublished) https://doi.org/10.1016/B978-0-323-91229-7.00004-0 https://doi.org/10.1016/B978-0-323-91229-7.00004-0 |
| spellingShingle | QD Chemistry QP Physiology RS Pharmacy and materia medica T Technology (General) Nor Hasmaliana, Abdul Manas Dayang Norulfairuz, Abang Zaidel Nur Izyan, Wan Azelee Siti Fatimah Zaharah, Mohd Fuzi Aizi Nor Mazila, Ramli Shalyda, Md Shaarani Rosli, Md. Illias Norsuhada, Abdul Karim Delivery of bioencapsulated proteins |
| title | Delivery of bioencapsulated proteins |
| title_full | Delivery of bioencapsulated proteins |
| title_fullStr | Delivery of bioencapsulated proteins |
| title_full_unstemmed | Delivery of bioencapsulated proteins |
| title_short | Delivery of bioencapsulated proteins |
| title_sort | delivery of bioencapsulated proteins |
| topic | QD Chemistry QP Physiology RS Pharmacy and materia medica T Technology (General) |
| url | http://umpir.ump.edu.my/id/eprint/37685/ http://umpir.ump.edu.my/id/eprint/37685/ http://umpir.ump.edu.my/id/eprint/37685/ http://umpir.ump.edu.my/id/eprint/37685/1/Delivery%20of%20bioencapsulated%20proteins.pdf http://umpir.ump.edu.my/id/eprint/37685/7/11.Delivery%20of%20bioencapsulated%20proteins.pdf |