Antifungal activity of biosynthesized silver nanoparticles mediated by neem leaf extract against aspergillus sp.
Silver nanoparticles (AgNPs) have attracted considerable attraction as excellent antifungal agents against various pathogens. In the present study, AgNPs were biosynthesized using neem leaf aqueous extract, and their antifungal properties were evaluated against Aspergillus sp. The formation of newly...
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| Format: | Article |
| Language: | English |
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AMG Transcend Association
2023
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| Online Access: | http://umpir.ump.edu.my/id/eprint/37604/ http://umpir.ump.edu.my/id/eprint/37604/1/Antifungal%20Activity%20of%20Biosynthesized%20Silver%20Nanoparticles%20Mediated.pdf |
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| author | Wan Nur Atiqah, Wan Shamsudin Che Ku Mohammad Faizal, Che Ku Yahya Siti Hajar Noor, Shaarani |
| author_facet | Wan Nur Atiqah, Wan Shamsudin Che Ku Mohammad Faizal, Che Ku Yahya Siti Hajar Noor, Shaarani |
| author_sort | Wan Nur Atiqah, Wan Shamsudin |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Silver nanoparticles (AgNPs) have attracted considerable attraction as excellent antifungal agents against various pathogens. In the present study, AgNPs were biosynthesized using neem leaf aqueous extract, and their antifungal properties were evaluated against Aspergillus sp. The formation of newly synthesized AgNPs was confirmed through visual observation by a change in the color of the solution, followed by an analysis of their surface plasmon resonance via UV-vis spectrophotometer. Further characterization of its crystalline nature and morphology structure was assessed by X-Ray Diffraction (XRD) and Field-emission Scanning Electron Microscope (FESEM), respectively. The result revealed that the synthesized AgNPs showed UV-vis spectra peak around 421 nm, are crystalline in nature, and have a spherical morphology with an average size of 20.13 ± 3.3 nm in diameter. Furthermore, these AgNPs exhibit excellent antifungal activity against the waterborne pathogen Aspergillus sp. on agar well diffusion assay with a maximum 26.54 ± 1.23 mm zone of inhibition. FESEM image revealed hyphal damage and deformation of fungus when treated with AgNPs, causing retardation of fungus growth for further reproduction. The results suggested that this biosynthesis AgNPs from neem leaf extract has great potential as an alternative antifungal agent for use in water treatment. |
| first_indexed | 2025-11-15T03:26:39Z |
| format | Article |
| id | ump-37604 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T03:26:39Z |
| publishDate | 2023 |
| publisher | AMG Transcend Association |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-376042023-05-16T00:39:38Z http://umpir.ump.edu.my/id/eprint/37604/ Antifungal activity of biosynthesized silver nanoparticles mediated by neem leaf extract against aspergillus sp. Wan Nur Atiqah, Wan Shamsudin Che Ku Mohammad Faizal, Che Ku Yahya Siti Hajar Noor, Shaarani QD Chemistry TP Chemical technology Silver nanoparticles (AgNPs) have attracted considerable attraction as excellent antifungal agents against various pathogens. In the present study, AgNPs were biosynthesized using neem leaf aqueous extract, and their antifungal properties were evaluated against Aspergillus sp. The formation of newly synthesized AgNPs was confirmed through visual observation by a change in the color of the solution, followed by an analysis of their surface plasmon resonance via UV-vis spectrophotometer. Further characterization of its crystalline nature and morphology structure was assessed by X-Ray Diffraction (XRD) and Field-emission Scanning Electron Microscope (FESEM), respectively. The result revealed that the synthesized AgNPs showed UV-vis spectra peak around 421 nm, are crystalline in nature, and have a spherical morphology with an average size of 20.13 ± 3.3 nm in diameter. Furthermore, these AgNPs exhibit excellent antifungal activity against the waterborne pathogen Aspergillus sp. on agar well diffusion assay with a maximum 26.54 ± 1.23 mm zone of inhibition. FESEM image revealed hyphal damage and deformation of fungus when treated with AgNPs, causing retardation of fungus growth for further reproduction. The results suggested that this biosynthesis AgNPs from neem leaf extract has great potential as an alternative antifungal agent for use in water treatment. AMG Transcend Association 2023 Article PeerReviewed pdf en cc_by_4 http://umpir.ump.edu.my/id/eprint/37604/1/Antifungal%20Activity%20of%20Biosynthesized%20Silver%20Nanoparticles%20Mediated.pdf Wan Nur Atiqah, Wan Shamsudin and Che Ku Mohammad Faizal, Che Ku Yahya and Siti Hajar Noor, Shaarani (2023) Antifungal activity of biosynthesized silver nanoparticles mediated by neem leaf extract against aspergillus sp. Biointerface Research in Applied Chemistry, 13 (6). p. 583. ISSN 2069-5837. (Published) https://doi.org/10.33263/BRIAC136.583 https://doi.org/10.33263/BRIAC136.583 |
| spellingShingle | QD Chemistry TP Chemical technology Wan Nur Atiqah, Wan Shamsudin Che Ku Mohammad Faizal, Che Ku Yahya Siti Hajar Noor, Shaarani Antifungal activity of biosynthesized silver nanoparticles mediated by neem leaf extract against aspergillus sp. |
| title | Antifungal activity of biosynthesized silver nanoparticles mediated by neem leaf extract against aspergillus sp. |
| title_full | Antifungal activity of biosynthesized silver nanoparticles mediated by neem leaf extract against aspergillus sp. |
| title_fullStr | Antifungal activity of biosynthesized silver nanoparticles mediated by neem leaf extract against aspergillus sp. |
| title_full_unstemmed | Antifungal activity of biosynthesized silver nanoparticles mediated by neem leaf extract against aspergillus sp. |
| title_short | Antifungal activity of biosynthesized silver nanoparticles mediated by neem leaf extract against aspergillus sp. |
| title_sort | antifungal activity of biosynthesized silver nanoparticles mediated by neem leaf extract against aspergillus sp. |
| topic | QD Chemistry TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/37604/ http://umpir.ump.edu.my/id/eprint/37604/ http://umpir.ump.edu.my/id/eprint/37604/ http://umpir.ump.edu.my/id/eprint/37604/1/Antifungal%20Activity%20of%20Biosynthesized%20Silver%20Nanoparticles%20Mediated.pdf |