Applications of nanomaterials for biosensor fabrication based on redox enzyme and protein: A mini-review
Redox enzyme and protein modified biosensors are commercially triumphant bioelectronic devices used in the point-of-care analysis. The use of nanotechnology derived nanomaterials during enzyme immobilization creates a synergistic effect by integrating recognition and catalytic properties with the el...
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| Format: | Article |
| Language: | English English |
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Penerbit Universiti Malaysia Pahang
2022
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| Online Access: | http://umpir.ump.edu.my/id/eprint/35992/ http://umpir.ump.edu.my/id/eprint/35992/1/Applications%20of%20Nanomaterials%20for%20Biosensor%20Fabrication%20Based%20on%20Redox%20Enzyme.pdf http://umpir.ump.edu.my/id/eprint/35992/7/Applications%20of%20Nanomaterials%20for%20Biosensor%20Fabrication.pdf |
| _version_ | 1848824923689058304 |
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| author | Kader, Md. Ashraful Kafi, A. K. M. Azmi, Nina Suhaity |
| author_facet | Kader, Md. Ashraful Kafi, A. K. M. Azmi, Nina Suhaity |
| author_sort | Kader, Md. Ashraful |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Redox enzyme and protein modified biosensors are commercially triumphant bioelectronic devices used in the point-of-care analysis. The use of nanotechnology derived nanomaterials during enzyme immobilization creates a synergistic effect by integrating recognition and catalytic properties with the electronic properties of nanomaterials. This synergy improves the sensitivity, conductivity stability, surface-to-volume ratio, selectivity, detection limit and other analytical features. This critical review focuses on the redox enzymes and proteins most frequently used in glucose and hydrogen peroxide sensing, such as horseradish peroxidase (HRP), glucose oxidase (GOx), hemoglobin (HB), and cytochrome C (Cyt c). Besides, we evaluate the state of art of this approach, selection of nanomaterials, preparation and immobilization mechanisms, their role and sensing applications. Besides advantages, we have discussed the pressing challenges of developing these sensors. This review will guide the research community to develop rational and highly efficient nanomaterial immobilized biosensors. |
| first_indexed | 2025-11-15T03:20:45Z |
| format | Article |
| id | ump-35992 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T03:20:45Z |
| publishDate | 2022 |
| publisher | Penerbit Universiti Malaysia Pahang |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-359922023-06-23T08:26:41Z http://umpir.ump.edu.my/id/eprint/35992/ Applications of nanomaterials for biosensor fabrication based on redox enzyme and protein: A mini-review Kader, Md. Ashraful Kafi, A. K. M. Azmi, Nina Suhaity QD Chemistry TP Chemical technology Redox enzyme and protein modified biosensors are commercially triumphant bioelectronic devices used in the point-of-care analysis. The use of nanotechnology derived nanomaterials during enzyme immobilization creates a synergistic effect by integrating recognition and catalytic properties with the electronic properties of nanomaterials. This synergy improves the sensitivity, conductivity stability, surface-to-volume ratio, selectivity, detection limit and other analytical features. This critical review focuses on the redox enzymes and proteins most frequently used in glucose and hydrogen peroxide sensing, such as horseradish peroxidase (HRP), glucose oxidase (GOx), hemoglobin (HB), and cytochrome C (Cyt c). Besides, we evaluate the state of art of this approach, selection of nanomaterials, preparation and immobilization mechanisms, their role and sensing applications. Besides advantages, we have discussed the pressing challenges of developing these sensors. This review will guide the research community to develop rational and highly efficient nanomaterial immobilized biosensors. Penerbit Universiti Malaysia Pahang 2022 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/35992/1/Applications%20of%20Nanomaterials%20for%20Biosensor%20Fabrication%20Based%20on%20Redox%20Enzyme.pdf pdf en cc_by_4 http://umpir.ump.edu.my/id/eprint/35992/7/Applications%20of%20Nanomaterials%20for%20Biosensor%20Fabrication.pdf Kader, Md. Ashraful and Kafi, A. K. M. and Azmi, Nina Suhaity (2022) Applications of nanomaterials for biosensor fabrication based on redox enzyme and protein: A mini-review. Current Science and Technology (CST), 2 (2). pp. 20-28. ISSN 2785-8804. (Published) https://journal.ump.edu.my/cst/article/view/9291 |
| spellingShingle | QD Chemistry TP Chemical technology Kader, Md. Ashraful Kafi, A. K. M. Azmi, Nina Suhaity Applications of nanomaterials for biosensor fabrication based on redox enzyme and protein: A mini-review |
| title | Applications of nanomaterials for biosensor fabrication based on redox enzyme and protein: A mini-review |
| title_full | Applications of nanomaterials for biosensor fabrication based on redox enzyme and protein: A mini-review |
| title_fullStr | Applications of nanomaterials for biosensor fabrication based on redox enzyme and protein: A mini-review |
| title_full_unstemmed | Applications of nanomaterials for biosensor fabrication based on redox enzyme and protein: A mini-review |
| title_short | Applications of nanomaterials for biosensor fabrication based on redox enzyme and protein: A mini-review |
| title_sort | applications of nanomaterials for biosensor fabrication based on redox enzyme and protein: a mini-review |
| topic | QD Chemistry TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/35992/ http://umpir.ump.edu.my/id/eprint/35992/ http://umpir.ump.edu.my/id/eprint/35992/1/Applications%20of%20Nanomaterials%20for%20Biosensor%20Fabrication%20Based%20on%20Redox%20Enzyme.pdf http://umpir.ump.edu.my/id/eprint/35992/7/Applications%20of%20Nanomaterials%20for%20Biosensor%20Fabrication.pdf |