Formulation and evaluation of antimicrobial herbosomal gel from Quercus infectoria extract
Nowadays, the use of herbal medicine is gaining importance for treating many diseases due to their significant effect and lesser side effects as compared to allopathic medicines. Phytosomal herbal formulations or herbosomes are better absorbed and produce better bioavailability than the conventional...
| Main Authors: | , , , , |
|---|---|
| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
Institute of Physics Publishing
2020
|
| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/35976/ http://umpir.ump.edu.my/id/eprint/35976/1/Formulation%20and%20evaluation%20of%20antimicrobial%20herbosomal%20gel%20from%20Quercus%20infectoria%20extract.pdf |
| _version_ | 1848824920109219840 |
|---|---|
| author | W. Y, Suzilla A., Izzati I, Isha A., Zalina V. K., Rajaletchumy |
| author_facet | W. Y, Suzilla A., Izzati I, Isha A., Zalina V. K., Rajaletchumy |
| author_sort | W. Y, Suzilla |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Nowadays, the use of herbal medicine is gaining importance for treating many diseases due to their significant effect and lesser side effects as compared to allopathic medicines. Phytosomal herbal formulations or herbosomes are better absorbed and produce better bioavailability than the conventional botanical extracts. Hence, this study is conducted to formulate the herbosomal gel from QI galls ethanolic extract. The QI gall was extracted using ethanol giving the percentage of yield 17%. For the High-Performance Liquid Chromatography analysis, it was revealed that the QI galls extract contains large amount of tannic acid (1794.18 mg/g) and small amount of gallic acid (76.22 mg/g). The formulation consists of 1.0% of Carbopol 940 were found to be the best formulation since it shows good physicochemical properties. pH value was 6.31 while the viscosity was 3482.3144 cps. Formulated gel showed good stability after 21 days of formulation by not showing significance changes in pH value, viscosity and spreadability. Disc diffusion method was used to determine the antimicrobial activity and the results showed the inhibition zone for P. aeruginosa was greater than S. aureus. As conclusion, the QI galls extract formulated herbosomes was showed promising results to be developed as a new antibacterial gel formulation. |
| first_indexed | 2025-11-15T03:20:41Z |
| format | Conference or Workshop Item |
| id | ump-35976 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T03:20:41Z |
| publishDate | 2020 |
| publisher | Institute of Physics Publishing |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-359762022-12-28T04:56:21Z http://umpir.ump.edu.my/id/eprint/35976/ Formulation and evaluation of antimicrobial herbosomal gel from Quercus infectoria extract W. Y, Suzilla A., Izzati I, Isha A., Zalina V. K., Rajaletchumy QD Chemistry T Technology (General) TA Engineering (General). Civil engineering (General) TP Chemical technology Nowadays, the use of herbal medicine is gaining importance for treating many diseases due to their significant effect and lesser side effects as compared to allopathic medicines. Phytosomal herbal formulations or herbosomes are better absorbed and produce better bioavailability than the conventional botanical extracts. Hence, this study is conducted to formulate the herbosomal gel from QI galls ethanolic extract. The QI gall was extracted using ethanol giving the percentage of yield 17%. For the High-Performance Liquid Chromatography analysis, it was revealed that the QI galls extract contains large amount of tannic acid (1794.18 mg/g) and small amount of gallic acid (76.22 mg/g). The formulation consists of 1.0% of Carbopol 940 were found to be the best formulation since it shows good physicochemical properties. pH value was 6.31 while the viscosity was 3482.3144 cps. Formulated gel showed good stability after 21 days of formulation by not showing significance changes in pH value, viscosity and spreadability. Disc diffusion method was used to determine the antimicrobial activity and the results showed the inhibition zone for P. aeruginosa was greater than S. aureus. As conclusion, the QI galls extract formulated herbosomes was showed promising results to be developed as a new antibacterial gel formulation. Institute of Physics Publishing 2020-03-04 Conference or Workshop Item PeerReviewed pdf en cc_by http://umpir.ump.edu.my/id/eprint/35976/1/Formulation%20and%20evaluation%20of%20antimicrobial%20herbosomal%20gel%20from%20Quercus%20infectoria%20extract.pdf W. Y, Suzilla and A., Izzati and I, Isha and A., Zalina and V. K., Rajaletchumy (2020) Formulation and evaluation of antimicrobial herbosomal gel from Quercus infectoria extract. In: IOP Conference Series: Materials Science and Engineering, Energy Security and Chemical Engineering Congress , 17-19 July 2019 , Kuala Lumpur, Malaysia. pp. 1-15., 736 (022030). ISSN 1757-8981 (Published) https://doi.org/10.1088/1757-899X/736/2/022030 |
| spellingShingle | QD Chemistry T Technology (General) TA Engineering (General). Civil engineering (General) TP Chemical technology W. Y, Suzilla A., Izzati I, Isha A., Zalina V. K., Rajaletchumy Formulation and evaluation of antimicrobial herbosomal gel from Quercus infectoria extract |
| title | Formulation and evaluation of antimicrobial herbosomal gel from Quercus infectoria extract |
| title_full | Formulation and evaluation of antimicrobial herbosomal gel from Quercus infectoria extract |
| title_fullStr | Formulation and evaluation of antimicrobial herbosomal gel from Quercus infectoria extract |
| title_full_unstemmed | Formulation and evaluation of antimicrobial herbosomal gel from Quercus infectoria extract |
| title_short | Formulation and evaluation of antimicrobial herbosomal gel from Quercus infectoria extract |
| title_sort | formulation and evaluation of antimicrobial herbosomal gel from quercus infectoria extract |
| topic | QD Chemistry T Technology (General) TA Engineering (General). Civil engineering (General) TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/35976/ http://umpir.ump.edu.my/id/eprint/35976/ http://umpir.ump.edu.my/id/eprint/35976/1/Formulation%20and%20evaluation%20of%20antimicrobial%20herbosomal%20gel%20from%20Quercus%20infectoria%20extract.pdf |