Preparation and characterization of deer velvet antler/polyvinyl alcohol (DVA/PVA) scaffold for bone tissue engineering
Combining synthetic polymer with inorganic bioactive elements has been an exciting route for developing tissue engineering scaffolds, in particular for bone tissue regeneration. In this study we report the fabrication of novel porous scaffold composed of polyvinyl alcohol/ deer velvet antler (DVA/PV...
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| Format: | Conference or Workshop Item |
| Language: | English English |
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Elsevier Ltd
2021
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| Online Access: | http://umpir.ump.edu.my/id/eprint/35464/ http://umpir.ump.edu.my/id/eprint/35464/1/Preparation%20and%20characterization%20of%20deer%20velvet%20antler_polyvinyl%20alcohol%20%28DVA_PVA%29%20scaffold.pdf http://umpir.ump.edu.my/id/eprint/35464/2/Preparation%20and%20characterization%20of%20deer%20velvet%20antler_polyvinyl%20alcohol%20%28DVA_PVA%29%20scaffold_Abs.pdf |
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| author | Hazrulrizawati, Hamid Muhamad Zubbair Ammar, Khairul Anuar Farah Hanani, Zulkifli |
| author_facet | Hazrulrizawati, Hamid Muhamad Zubbair Ammar, Khairul Anuar Farah Hanani, Zulkifli |
| author_sort | Hazrulrizawati, Hamid |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Combining synthetic polymer with inorganic bioactive elements has been an exciting route for developing tissue engineering scaffolds, in particular for bone tissue regeneration. In this study we report the fabrication of novel porous scaffold composed of polyvinyl alcohol/ deer velvet antler (DVA/PVA) via freeze-drying technique. The, mineral content of deer velvet antler analyzed by ICPMS showed high content of calcium and phosphorus. Morphological observation revealed that the incorporation of DVA in the polymer matrix with the porous structures ranging from 35 to 100 mm. The FTIR demonstrated chemical interaction between DVA and PVA due to the reaction between calcium ions with hydroxyl. Thermal analysis showed significant temperature increase from 146.34°C to 384.48°C due to the degradation of the side chain of PVA and decomposition of the carbonate ions. The swelling behavior, the porosity, and the degradation rate of the DVA/PVA scaffold were meet the physiological demands of bone regeneration. After 7 days, DVA/PVA scaffold showed the increasing of water absorption and low degradation rate. Thus, the developed scaffold is believed to have a potential to be effectively used in bone tissue engineering applications. |
| first_indexed | 2025-11-15T03:18:33Z |
| format | Conference or Workshop Item |
| id | ump-35464 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T03:18:33Z |
| publishDate | 2021 |
| publisher | Elsevier Ltd |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-354642022-10-28T01:27:13Z http://umpir.ump.edu.my/id/eprint/35464/ Preparation and characterization of deer velvet antler/polyvinyl alcohol (DVA/PVA) scaffold for bone tissue engineering Hazrulrizawati, Hamid Muhamad Zubbair Ammar, Khairul Anuar Farah Hanani, Zulkifli HD Industries. Land use. Labor Q Science (General) T Technology (General) Combining synthetic polymer with inorganic bioactive elements has been an exciting route for developing tissue engineering scaffolds, in particular for bone tissue regeneration. In this study we report the fabrication of novel porous scaffold composed of polyvinyl alcohol/ deer velvet antler (DVA/PVA) via freeze-drying technique. The, mineral content of deer velvet antler analyzed by ICPMS showed high content of calcium and phosphorus. Morphological observation revealed that the incorporation of DVA in the polymer matrix with the porous structures ranging from 35 to 100 mm. The FTIR demonstrated chemical interaction between DVA and PVA due to the reaction between calcium ions with hydroxyl. Thermal analysis showed significant temperature increase from 146.34°C to 384.48°C due to the degradation of the side chain of PVA and decomposition of the carbonate ions. The swelling behavior, the porosity, and the degradation rate of the DVA/PVA scaffold were meet the physiological demands of bone regeneration. After 7 days, DVA/PVA scaffold showed the increasing of water absorption and low degradation rate. Thus, the developed scaffold is believed to have a potential to be effectively used in bone tissue engineering applications. Elsevier Ltd 2021 Conference or Workshop Item PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/35464/1/Preparation%20and%20characterization%20of%20deer%20velvet%20antler_polyvinyl%20alcohol%20%28DVA_PVA%29%20scaffold.pdf pdf en http://umpir.ump.edu.my/id/eprint/35464/2/Preparation%20and%20characterization%20of%20deer%20velvet%20antler_polyvinyl%20alcohol%20%28DVA_PVA%29%20scaffold_Abs.pdf Hazrulrizawati, Hamid and Muhamad Zubbair Ammar, Khairul Anuar and Farah Hanani, Zulkifli (2021) Preparation and characterization of deer velvet antler/polyvinyl alcohol (DVA/PVA) scaffold for bone tissue engineering. In: Materials Today: Proceedings, 3rd Symposium on Industrial Science and Technology (SISTEC2021) , 25-26 August 2021 , Virtual Conference, Universiti Malaysia Pahang, Malaysia. pp. 1332-1337., 51 (Part 2). ISSN 2214-7853 (Published) https://doi.org/10.1016/j.matpr.2021.11.377 |
| spellingShingle | HD Industries. Land use. Labor Q Science (General) T Technology (General) Hazrulrizawati, Hamid Muhamad Zubbair Ammar, Khairul Anuar Farah Hanani, Zulkifli Preparation and characterization of deer velvet antler/polyvinyl alcohol (DVA/PVA) scaffold for bone tissue engineering |
| title | Preparation and characterization of deer velvet antler/polyvinyl alcohol (DVA/PVA) scaffold for bone tissue engineering |
| title_full | Preparation and characterization of deer velvet antler/polyvinyl alcohol (DVA/PVA) scaffold for bone tissue engineering |
| title_fullStr | Preparation and characterization of deer velvet antler/polyvinyl alcohol (DVA/PVA) scaffold for bone tissue engineering |
| title_full_unstemmed | Preparation and characterization of deer velvet antler/polyvinyl alcohol (DVA/PVA) scaffold for bone tissue engineering |
| title_short | Preparation and characterization of deer velvet antler/polyvinyl alcohol (DVA/PVA) scaffold for bone tissue engineering |
| title_sort | preparation and characterization of deer velvet antler/polyvinyl alcohol (dva/pva) scaffold for bone tissue engineering |
| topic | HD Industries. Land use. Labor Q Science (General) T Technology (General) |
| url | http://umpir.ump.edu.my/id/eprint/35464/ http://umpir.ump.edu.my/id/eprint/35464/ http://umpir.ump.edu.my/id/eprint/35464/1/Preparation%20and%20characterization%20of%20deer%20velvet%20antler_polyvinyl%20alcohol%20%28DVA_PVA%29%20scaffold.pdf http://umpir.ump.edu.my/id/eprint/35464/2/Preparation%20and%20characterization%20of%20deer%20velvet%20antler_polyvinyl%20alcohol%20%28DVA_PVA%29%20scaffold_Abs.pdf |