Bioconversion of glycerol waste to ethanol by Escherichia coli and optimisation of process parameters

Biofuel is one of the best ways to reduce our dependence on fossil fuels. Ever since commercial biodiesel production began, waste glycerol, the biodiesel byproduct, has gained researchers’ interest, especially its recycling. Here, we explored using glycerol residue (carbon source) as a substrate in...

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Main Authors: Reddy, Chilakamarry Chaitanya, Mimi Sakinah, A. M., Zularisam, A. W., Khilji, Irshad Ahmad, Sirohi, Ranjna, Reddy, Venugopal Jayarama
Format: Article
Language:English
Published: CSIR-NIScPR, India 2022
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/35107/
http://umpir.ump.edu.my/id/eprint/35107/1/Bioconversion%20of%20glycerol%20waste%20to%20ethanol.pdf
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author Reddy, Chilakamarry Chaitanya
Mimi Sakinah, A. M.
Zularisam, A. W.
Khilji, Irshad Ahmad
Sirohi, Ranjna
Reddy, Venugopal Jayarama
author_facet Reddy, Chilakamarry Chaitanya
Mimi Sakinah, A. M.
Zularisam, A. W.
Khilji, Irshad Ahmad
Sirohi, Ranjna
Reddy, Venugopal Jayarama
author_sort Reddy, Chilakamarry Chaitanya
building UMP Institutional Repository
collection Online Access
description Biofuel is one of the best ways to reduce our dependence on fossil fuels. Ever since commercial biodiesel production began, waste glycerol, the biodiesel byproduct, has gained researchers’ interest, especially its recycling. Here, we explored using glycerol residue (carbon source) as a substrate in the fermentation process for ethanol production by Escherichia coli K12 in anaerobic conditions. The factors affecting the ethanol production was optimised by response surface methodology (RSM). Significant variables that impact the ethanol concentration were pH, temperature and the substrate, with a statistically significant effect (P <0.05) on ethanol formation. The significant factor was analyzed by the Box-Behnken design. The optimum conditions for bioethanol formation using glycerol as substrate was obtained at pH 7 and temperature 37°C. The ethanol productivity was 0.77 g/L/h. The ethanol concentration of 9.2 g/L achieved from glycerol residue was close to the theoretical value with the fermentation achieved at optimised terms.
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publisher CSIR-NIScPR, India
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spelling ump-351072022-09-06T09:03:12Z http://umpir.ump.edu.my/id/eprint/35107/ Bioconversion of glycerol waste to ethanol by Escherichia coli and optimisation of process parameters Reddy, Chilakamarry Chaitanya Mimi Sakinah, A. M. Zularisam, A. W. Khilji, Irshad Ahmad Sirohi, Ranjna Reddy, Venugopal Jayarama TP Chemical technology Biofuel is one of the best ways to reduce our dependence on fossil fuels. Ever since commercial biodiesel production began, waste glycerol, the biodiesel byproduct, has gained researchers’ interest, especially its recycling. Here, we explored using glycerol residue (carbon source) as a substrate in the fermentation process for ethanol production by Escherichia coli K12 in anaerobic conditions. The factors affecting the ethanol production was optimised by response surface methodology (RSM). Significant variables that impact the ethanol concentration were pH, temperature and the substrate, with a statistically significant effect (P <0.05) on ethanol formation. The significant factor was analyzed by the Box-Behnken design. The optimum conditions for bioethanol formation using glycerol as substrate was obtained at pH 7 and temperature 37°C. The ethanol productivity was 0.77 g/L/h. The ethanol concentration of 9.2 g/L achieved from glycerol residue was close to the theoretical value with the fermentation achieved at optimised terms. CSIR-NIScPR, India 2022 Article PeerReviewed pdf en cc_by_nc_nd_4 http://umpir.ump.edu.my/id/eprint/35107/1/Bioconversion%20of%20glycerol%20waste%20to%20ethanol.pdf Reddy, Chilakamarry Chaitanya and Mimi Sakinah, A. M. and Zularisam, A. W. and Khilji, Irshad Ahmad and Sirohi, Ranjna and Reddy, Venugopal Jayarama (2022) Bioconversion of glycerol waste to ethanol by Escherichia coli and optimisation of process parameters. Indian Journal of Experimental Biology (IJEB), 60 (9). pp. 681-688. (Published) http://op.niscpr.res.in/index.php/IJEB/article/view/65145 http://op.niscpr.res.in/index.php/IJEB/article/view/65145
spellingShingle TP Chemical technology
Reddy, Chilakamarry Chaitanya
Mimi Sakinah, A. M.
Zularisam, A. W.
Khilji, Irshad Ahmad
Sirohi, Ranjna
Reddy, Venugopal Jayarama
Bioconversion of glycerol waste to ethanol by Escherichia coli and optimisation of process parameters
title Bioconversion of glycerol waste to ethanol by Escherichia coli and optimisation of process parameters
title_full Bioconversion of glycerol waste to ethanol by Escherichia coli and optimisation of process parameters
title_fullStr Bioconversion of glycerol waste to ethanol by Escherichia coli and optimisation of process parameters
title_full_unstemmed Bioconversion of glycerol waste to ethanol by Escherichia coli and optimisation of process parameters
title_short Bioconversion of glycerol waste to ethanol by Escherichia coli and optimisation of process parameters
title_sort bioconversion of glycerol waste to ethanol by escherichia coli and optimisation of process parameters
topic TP Chemical technology
url http://umpir.ump.edu.my/id/eprint/35107/
http://umpir.ump.edu.my/id/eprint/35107/
http://umpir.ump.edu.my/id/eprint/35107/
http://umpir.ump.edu.my/id/eprint/35107/1/Bioconversion%20of%20glycerol%20waste%20to%20ethanol.pdf