Needleless Electrospun Nanofibers for Drug Delivery Systems

Bubble, hollow tube, roller, wire-based and slit-surface needleless electrospinning units are discussed on the basis of the entrepreneurial product cycle of prototype development translating into commercial units. The controlled release of curcumin from a scaffold under physiological simulated condi...

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Bibliographic Details
Main Authors: Jolius, Gimbun, Ramakrishnan, Ramprasath, Ramakrishnan, Praveen, Ranganathan, Balu
Other Authors: Praveen, K.M.
Format: Book Chapter
Language:English
Published: CRC Press 2022
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/35005/
http://umpir.ump.edu.my/id/eprint/35005/2/Needleless%20Electrospun%20Nanofibers%20for%20Drug%20Delivery%20Systems.pdf
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Summary:Bubble, hollow tube, roller, wire-based and slit-surface needleless electrospinning units are discussed on the basis of the entrepreneurial product cycle of prototype development translating into commercial units. The controlled release of curcumin from a scaffold under physiological simulated conditions shows a significant release of curcumin within 48 hours of test. This work may serve as a useful guide for a drug delivery industry to process nanofibers at a large and continuous scale with a blend of drugs in the nanofibers using wire electrode electrospinning. This work may also serve as a useful guide to obtain a high-quality nanofiber from a needleless electrospinning process for drug delivery applications.