An updated review of type 1 diabetes in Malaysia

The emerging phenomenon of early-onset type 2 diabetes mellitus (T2D) among Malaysians and misclassification of diabetes types may impact the estimates of prevalence and incidence of type 1 diabetes mellitus (T1D). From previous studies, the prevalence of T1D among the major ethnic groups in Malaysi...

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Main Author: Ahmad Mahfuz, Gazali
Format: Article
Language:English
Published: Kulliyyah of Medicine, IIUM 2022
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/34745/
http://umpir.ump.edu.my/id/eprint/34745/1/An%20updated%20review%20of%20type%201%20diabetes%20in%20Malaysia.pdf
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author Ahmad Mahfuz, Gazali
author_facet Ahmad Mahfuz, Gazali
author_sort Ahmad Mahfuz, Gazali
building UMP Institutional Repository
collection Online Access
description The emerging phenomenon of early-onset type 2 diabetes mellitus (T2D) among Malaysians and misclassification of diabetes types may impact the estimates of prevalence and incidence of type 1 diabetes mellitus (T1D). From previous studies, the prevalence of T1D among the major ethnic groups in Malaysia was seen highest among Chinese, followed by Malays and Indians. More than half of the patients had diabetes ketoacidosis (DKA). This corresponded with the overall poor glycaemic control seen. However, the incidence of chronic complications, such as nephropathy, was lower. The prevalence of autoantibodies was reported highest for anti-islet cell antibody (ICA). As part of treatment, most Malaysian children had one or two daily insulin injections. Generally, older patients responded better to insulin therapy and yielded better glycaemic control than younger patients. While significant advances have been made in understanding T1D in the Malaysian population, more research is warranted to improve the clinical assessment and outcome of the disease. The present narrative review aims to summarise the overall status of T1D in Malaysia, which includes epidemiology, clinical presentation, diagnosis, complications, and management.
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spelling ump-347452022-07-21T02:54:43Z http://umpir.ump.edu.my/id/eprint/34745/ An updated review of type 1 diabetes in Malaysia Ahmad Mahfuz, Gazali RA Public aspects of medicine RC Internal medicine The emerging phenomenon of early-onset type 2 diabetes mellitus (T2D) among Malaysians and misclassification of diabetes types may impact the estimates of prevalence and incidence of type 1 diabetes mellitus (T1D). From previous studies, the prevalence of T1D among the major ethnic groups in Malaysia was seen highest among Chinese, followed by Malays and Indians. More than half of the patients had diabetes ketoacidosis (DKA). This corresponded with the overall poor glycaemic control seen. However, the incidence of chronic complications, such as nephropathy, was lower. The prevalence of autoantibodies was reported highest for anti-islet cell antibody (ICA). As part of treatment, most Malaysian children had one or two daily insulin injections. Generally, older patients responded better to insulin therapy and yielded better glycaemic control than younger patients. While significant advances have been made in understanding T1D in the Malaysian population, more research is warranted to improve the clinical assessment and outcome of the disease. The present narrative review aims to summarise the overall status of T1D in Malaysia, which includes epidemiology, clinical presentation, diagnosis, complications, and management. Kulliyyah of Medicine, IIUM 2022-07 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/34745/1/An%20updated%20review%20of%20type%201%20diabetes%20in%20Malaysia.pdf Ahmad Mahfuz, Gazali (2022) An updated review of type 1 diabetes in Malaysia. IIUM Medical Journal Malaysia, 21 (3). 15 -24. ISSN 2735-2285. (Published) https://doi.org/10.31436/imjm.v21i3 https://doi.org/10.31436/imjm.v21i3
spellingShingle RA Public aspects of medicine
RC Internal medicine
Ahmad Mahfuz, Gazali
An updated review of type 1 diabetes in Malaysia
title An updated review of type 1 diabetes in Malaysia
title_full An updated review of type 1 diabetes in Malaysia
title_fullStr An updated review of type 1 diabetes in Malaysia
title_full_unstemmed An updated review of type 1 diabetes in Malaysia
title_short An updated review of type 1 diabetes in Malaysia
title_sort updated review of type 1 diabetes in malaysia
topic RA Public aspects of medicine
RC Internal medicine
url http://umpir.ump.edu.my/id/eprint/34745/
http://umpir.ump.edu.my/id/eprint/34745/
http://umpir.ump.edu.my/id/eprint/34745/
http://umpir.ump.edu.my/id/eprint/34745/1/An%20updated%20review%20of%20type%201%20diabetes%20in%20Malaysia.pdf