Intensification of phenolic acids extraction from Aleppo oak via probe type sonication method: Kinetic, antioxidant and cost evaluation

This work aimed to evaluate the optimum conditions for efficient extraction of phenolic acids, namely gallic acid (GA) and tannic acid (TA) from Aleppo oak by ultrasonic-probe assisted extraction (UPAE) method. Furthermore, an extensive study on kinetic, antioxidant activity and cost evaluation aspe...

Full description

Bibliographic Details
Main Authors: Nuramira Fateha, Sukor, Rohayu, Jusoh, Nur Syahirah, Kamarudin
Format: Article
Language:English
Published: Elsevier Ltd 2021
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/34077/
http://umpir.ump.edu.my/id/eprint/34077/13/Intensification%20of%20phenolic%20acids.pdf
_version_ 1848824413903912960
author Nuramira Fateha, Sukor
Rohayu, Jusoh
Nur Syahirah, Kamarudin
author_facet Nuramira Fateha, Sukor
Rohayu, Jusoh
Nur Syahirah, Kamarudin
author_sort Nuramira Fateha, Sukor
building UMP Institutional Repository
collection Online Access
description This work aimed to evaluate the optimum conditions for efficient extraction of phenolic acids, namely gallic acid (GA) and tannic acid (TA) from Aleppo oak by ultrasonic-probe assisted extraction (UPAE) method. Furthermore, an extensive study on kinetic, antioxidant activity and cost evaluation aspects in comparison with classical hydro-distillation extraction (CHDE) method was also examined. Sonication demonstrated a superior effect on the extraction of target compounds in which the UPAE method was seven times more efficient compared to the classical hydro-distillation extraction (CHDE) method. Result revealed that under optimized optimum condition of 40% duty cycle and 70 °C extraction temperature, GA and TA were yielded at 870.90 ± 0.03 mg GAE/g and 3157.97 ± 0.05 mg TAE/g, respectively. Kinetic analysis affirmed the extraction rate as controlling factor in extracting phenolic acids. Strong antioxidant activity was observed at a IC50, 26.57 ± 0.03 μg/mL. Besides, the cost assessment study indicates that the extraction process requires US$ 0.25 and US$ 0.06 per mg/g extracts produced for CHDE and UPAE, respectively. Notably, findings revealed that UPAE method is four-fold more cost-effective compared to the CHDE method, providing a new direction for extracting active compounds from complex plants.
first_indexed 2025-11-15T03:12:39Z
format Article
id ump-34077
institution Universiti Malaysia Pahang
institution_category Local University
language English
last_indexed 2025-11-15T03:12:39Z
publishDate 2021
publisher Elsevier Ltd
recordtype eprints
repository_type Digital Repository
spelling ump-340772022-05-12T07:19:31Z http://umpir.ump.edu.my/id/eprint/34077/ Intensification of phenolic acids extraction from Aleppo oak via probe type sonication method: Kinetic, antioxidant and cost evaluation Nuramira Fateha, Sukor Rohayu, Jusoh Nur Syahirah, Kamarudin TP Chemical technology This work aimed to evaluate the optimum conditions for efficient extraction of phenolic acids, namely gallic acid (GA) and tannic acid (TA) from Aleppo oak by ultrasonic-probe assisted extraction (UPAE) method. Furthermore, an extensive study on kinetic, antioxidant activity and cost evaluation aspects in comparison with classical hydro-distillation extraction (CHDE) method was also examined. Sonication demonstrated a superior effect on the extraction of target compounds in which the UPAE method was seven times more efficient compared to the classical hydro-distillation extraction (CHDE) method. Result revealed that under optimized optimum condition of 40% duty cycle and 70 °C extraction temperature, GA and TA were yielded at 870.90 ± 0.03 mg GAE/g and 3157.97 ± 0.05 mg TAE/g, respectively. Kinetic analysis affirmed the extraction rate as controlling factor in extracting phenolic acids. Strong antioxidant activity was observed at a IC50, 26.57 ± 0.03 μg/mL. Besides, the cost assessment study indicates that the extraction process requires US$ 0.25 and US$ 0.06 per mg/g extracts produced for CHDE and UPAE, respectively. Notably, findings revealed that UPAE method is four-fold more cost-effective compared to the CHDE method, providing a new direction for extracting active compounds from complex plants. Elsevier Ltd 2021 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/34077/13/Intensification%20of%20phenolic%20acids.pdf Nuramira Fateha, Sukor and Rohayu, Jusoh and Nur Syahirah, Kamarudin (2021) Intensification of phenolic acids extraction from Aleppo oak via probe type sonication method: Kinetic, antioxidant and cost evaluation. Chemical Engineering Research and Design, 166. pp. 227-236. ISSN 0263-8762. (Published) https://doi.org/10.1016/j.cherd.2020.11.019 https://doi.org/10.1016/j.cherd.2020.11.019
spellingShingle TP Chemical technology
Nuramira Fateha, Sukor
Rohayu, Jusoh
Nur Syahirah, Kamarudin
Intensification of phenolic acids extraction from Aleppo oak via probe type sonication method: Kinetic, antioxidant and cost evaluation
title Intensification of phenolic acids extraction from Aleppo oak via probe type sonication method: Kinetic, antioxidant and cost evaluation
title_full Intensification of phenolic acids extraction from Aleppo oak via probe type sonication method: Kinetic, antioxidant and cost evaluation
title_fullStr Intensification of phenolic acids extraction from Aleppo oak via probe type sonication method: Kinetic, antioxidant and cost evaluation
title_full_unstemmed Intensification of phenolic acids extraction from Aleppo oak via probe type sonication method: Kinetic, antioxidant and cost evaluation
title_short Intensification of phenolic acids extraction from Aleppo oak via probe type sonication method: Kinetic, antioxidant and cost evaluation
title_sort intensification of phenolic acids extraction from aleppo oak via probe type sonication method: kinetic, antioxidant and cost evaluation
topic TP Chemical technology
url http://umpir.ump.edu.my/id/eprint/34077/
http://umpir.ump.edu.my/id/eprint/34077/
http://umpir.ump.edu.my/id/eprint/34077/
http://umpir.ump.edu.my/id/eprint/34077/13/Intensification%20of%20phenolic%20acids.pdf