Microwave-assisted extraction of phenolic compounds from Carica papaya leaves: An optimization study and LC-QTOF-MS analysis
Carica papaya is a well-known plant with diverse importance to human beings. The efficacy of microwave-assisted extraction (MAE) in the recovery of phenolic compounds from C. papaya leaf was investigated in this study. The MAE process variables were optimized using response surface method; at the op...
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| Format: | Article |
| Language: | English |
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Elsevier B.V.
2021
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| Online Access: | http://umpir.ump.edu.my/id/eprint/33173/ http://umpir.ump.edu.my/id/eprint/33173/1/Microwave-assisted%20extraction%20of%20phenolic%20compounds%20from%20Carica%20papaya%20leaves.pdf |
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| author | Alara, Oluwaseun Ruth Abdurahman, N.H. Ali, H.A. Zain, N.M. |
| author_facet | Alara, Oluwaseun Ruth Abdurahman, N.H. Ali, H.A. Zain, N.M. |
| author_sort | Alara, Oluwaseun Ruth |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Carica papaya is a well-known plant with diverse importance to human beings. The efficacy of microwave-assisted extraction (MAE) in the recovery of phenolic compounds from C. papaya leaf was investigated in this study. The MAE process variables were optimized using response surface method; at the optimized conditions, the embedded phenolic compounds in the extract were identified through LC-QTOF-MS analysis. The results showed that the best MAE conditions were: time of irradiation at 3 min; microwave power of 420 W; feed-to-solvent ratio of 1:12 g/mL; and solvent concentration of 56% ethanol/water to achieve 102.59 mg GAE/g d.w. of total phenolic content (TPC). At these conditions, an aggregate of 72 phenolic compounds was tentatively identified. These results infer that MAE as a technique can recover phenolic compounds from C. papaya leaf. Hence, the identified compounds can further be quantified with their respective pharmacological properties in future studies. |
| first_indexed | 2025-11-15T03:09:08Z |
| format | Article |
| id | ump-33173 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T03:09:08Z |
| publishDate | 2021 |
| publisher | Elsevier B.V. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-331732022-11-10T03:38:48Z http://umpir.ump.edu.my/id/eprint/33173/ Microwave-assisted extraction of phenolic compounds from Carica papaya leaves: An optimization study and LC-QTOF-MS analysis Alara, Oluwaseun Ruth Abdurahman, N.H. Ali, H.A. Zain, N.M. QD Chemistry T Technology (General) TA Engineering (General). Civil engineering (General) TP Chemical technology Carica papaya is a well-known plant with diverse importance to human beings. The efficacy of microwave-assisted extraction (MAE) in the recovery of phenolic compounds from C. papaya leaf was investigated in this study. The MAE process variables were optimized using response surface method; at the optimized conditions, the embedded phenolic compounds in the extract were identified through LC-QTOF-MS analysis. The results showed that the best MAE conditions were: time of irradiation at 3 min; microwave power of 420 W; feed-to-solvent ratio of 1:12 g/mL; and solvent concentration of 56% ethanol/water to achieve 102.59 mg GAE/g d.w. of total phenolic content (TPC). At these conditions, an aggregate of 72 phenolic compounds was tentatively identified. These results infer that MAE as a technique can recover phenolic compounds from C. papaya leaf. Hence, the identified compounds can further be quantified with their respective pharmacological properties in future studies. Elsevier B.V. 2021-06 Article PeerReviewed pdf en cc_by_nc_nd_4 http://umpir.ump.edu.my/id/eprint/33173/1/Microwave-assisted%20extraction%20of%20phenolic%20compounds%20from%20Carica%20papaya%20leaves.pdf Alara, Oluwaseun Ruth and Abdurahman, N.H. and Ali, H.A. and Zain, N.M. (2021) Microwave-assisted extraction of phenolic compounds from Carica papaya leaves: An optimization study and LC-QTOF-MS analysis. Future Foods, 3 (100035). pp. 1-8. ISSN 2666-8335. (Published) https://doi.org/ 10.1016/j.fufo.2021.100035 https://doi.org/ 10.1016/j.fufo.2021.100035 |
| spellingShingle | QD Chemistry T Technology (General) TA Engineering (General). Civil engineering (General) TP Chemical technology Alara, Oluwaseun Ruth Abdurahman, N.H. Ali, H.A. Zain, N.M. Microwave-assisted extraction of phenolic compounds from Carica papaya leaves: An optimization study and LC-QTOF-MS analysis |
| title | Microwave-assisted extraction of phenolic compounds from Carica papaya leaves: An optimization study and LC-QTOF-MS analysis |
| title_full | Microwave-assisted extraction of phenolic compounds from Carica papaya leaves: An optimization study and LC-QTOF-MS analysis |
| title_fullStr | Microwave-assisted extraction of phenolic compounds from Carica papaya leaves: An optimization study and LC-QTOF-MS analysis |
| title_full_unstemmed | Microwave-assisted extraction of phenolic compounds from Carica papaya leaves: An optimization study and LC-QTOF-MS analysis |
| title_short | Microwave-assisted extraction of phenolic compounds from Carica papaya leaves: An optimization study and LC-QTOF-MS analysis |
| title_sort | microwave-assisted extraction of phenolic compounds from carica papaya leaves: an optimization study and lc-qtof-ms analysis |
| topic | QD Chemistry T Technology (General) TA Engineering (General). Civil engineering (General) TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/33173/ http://umpir.ump.edu.my/id/eprint/33173/ http://umpir.ump.edu.my/id/eprint/33173/ http://umpir.ump.edu.my/id/eprint/33173/1/Microwave-assisted%20extraction%20of%20phenolic%20compounds%20from%20Carica%20papaya%20leaves.pdf |