In vitro and in vivo cytotoxic effects of chlorella against various types of cancer
Chlorella is one of the microalgae that had been studied intensively owing to its rapid growth and easily cultured at a large scale compared to other microalgae and valuable nutrient compositions. Numerous studies have observed that Chlorella possess various health benefit including antioxidant, ant...
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| Format: | Article |
| Language: | English |
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Kulliyyah of Medicine, IIUM
2021
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| Online Access: | http://umpir.ump.edu.my/id/eprint/32839/ http://umpir.ump.edu.my/id/eprint/32839/1/In%20vitro%20and%20in%20vivo%20cytotoxic%20effects%20of%20chlorella%20against%20various%20types%20of%20cancer.pdf |
| _version_ | 1848824120775540736 |
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| author | Ahmad Raus, R. Noor Suhana, Adzahar Basri, D. F. Latif, E. S. Sallehudin, N. J. |
| author_facet | Ahmad Raus, R. Noor Suhana, Adzahar Basri, D. F. Latif, E. S. Sallehudin, N. J. |
| author_sort | Ahmad Raus, R. |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Chlorella is one of the microalgae that had been studied intensively owing to its rapid growth and easily cultured at a large scale compared to other microalgae and valuable nutrient compositions. Numerous studies have observed that Chlorella possess various health benefit including antioxidant, anti-cholesterol, anti-inflammatory, and antiproliferative effect against many types of cancer. In this review paper, the effects of various Chlorella species against cancer cells and animal induced cancer are discussed and an overview on Chlorella is briefed. The Chlorella deleterious effect on cancer through various mechanisms such as enhancement of immune system and apoptosis; improving lipid peroxidation; synthesis and expression of the protein-degrading matrix; and preventing the formation of new blood vessels are elaborated as well. Based on the findings of many studies reported in this article, it can be suggested that Chlorella has the potential in supporting cancer therapy and may develop to become an anti-cancer agent. |
| first_indexed | 2025-11-15T03:07:59Z |
| format | Article |
| id | ump-32839 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T03:07:59Z |
| publishDate | 2021 |
| publisher | Kulliyyah of Medicine, IIUM |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-328392022-05-27T04:30:59Z http://umpir.ump.edu.my/id/eprint/32839/ In vitro and in vivo cytotoxic effects of chlorella against various types of cancer Ahmad Raus, R. Noor Suhana, Adzahar Basri, D. F. Latif, E. S. Sallehudin, N. J. RC Internal medicine RM Therapeutics. Pharmacology T Technology (General) Chlorella is one of the microalgae that had been studied intensively owing to its rapid growth and easily cultured at a large scale compared to other microalgae and valuable nutrient compositions. Numerous studies have observed that Chlorella possess various health benefit including antioxidant, anti-cholesterol, anti-inflammatory, and antiproliferative effect against many types of cancer. In this review paper, the effects of various Chlorella species against cancer cells and animal induced cancer are discussed and an overview on Chlorella is briefed. The Chlorella deleterious effect on cancer through various mechanisms such as enhancement of immune system and apoptosis; improving lipid peroxidation; synthesis and expression of the protein-degrading matrix; and preventing the formation of new blood vessels are elaborated as well. Based on the findings of many studies reported in this article, it can be suggested that Chlorella has the potential in supporting cancer therapy and may develop to become an anti-cancer agent. Kulliyyah of Medicine, IIUM 2021-01 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/32839/1/In%20vitro%20and%20in%20vivo%20cytotoxic%20effects%20of%20chlorella%20against%20various%20types%20of%20cancer.pdf Ahmad Raus, R. and Noor Suhana, Adzahar and Basri, D. F. and Latif, E. S. and Sallehudin, N. J. (2021) In vitro and in vivo cytotoxic effects of chlorella against various types of cancer. IIUM Medical Journal Malaysia, 20 (1). pp. 149-158. ISSN 2735-2285. (Published) https://doi.org/10.31436/IMJM.V20I1.1765 https://doi.org/10.31436/IMJM.V20I1.1765 |
| spellingShingle | RC Internal medicine RM Therapeutics. Pharmacology T Technology (General) Ahmad Raus, R. Noor Suhana, Adzahar Basri, D. F. Latif, E. S. Sallehudin, N. J. In vitro and in vivo cytotoxic effects of chlorella against various types of cancer |
| title | In vitro and in vivo cytotoxic effects of chlorella against various types of cancer |
| title_full | In vitro and in vivo cytotoxic effects of chlorella against various types of cancer |
| title_fullStr | In vitro and in vivo cytotoxic effects of chlorella against various types of cancer |
| title_full_unstemmed | In vitro and in vivo cytotoxic effects of chlorella against various types of cancer |
| title_short | In vitro and in vivo cytotoxic effects of chlorella against various types of cancer |
| title_sort | in vitro and in vivo cytotoxic effects of chlorella against various types of cancer |
| topic | RC Internal medicine RM Therapeutics. Pharmacology T Technology (General) |
| url | http://umpir.ump.edu.my/id/eprint/32839/ http://umpir.ump.edu.my/id/eprint/32839/ http://umpir.ump.edu.my/id/eprint/32839/ http://umpir.ump.edu.my/id/eprint/32839/1/In%20vitro%20and%20in%20vivo%20cytotoxic%20effects%20of%20chlorella%20against%20various%20types%20of%20cancer.pdf |